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anti-Phospholipase C gamma 2 (PLCG2) Antikörper

Bezeichnung:
anti-Phospholipase C gamma 2 Antikörper (PLCG2)
Auf www.antikoerper-online.de finden Sie aktuell 267 Phospholipase C gamma 2 (PLCG2) Antikörper von 24 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen Phospholipase C gamma 2 Kits (22) und Phospholipase C gamma 2 Proteine (4) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 312 Phospholipase C gamma 2 Produkte verfügbar.
Synonyme:
APLAID, FCAS3, Plcg-2, PLCgamma2

Meistgesuchte Reaktivitäten zu anti-Phospholipase C gamma 2 (PLCG2) Antikörper

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anti-Mouse (Murine) Phospholipase C gamma 2 Antikörper:

anti-Rat (Rattus) Phospholipase C gamma 2 Antikörper:

anti-Human Phospholipase C gamma 2 Antikörper:

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Am meisten referenzierte anti-Phospholipase C gamma 2 Antikörper

  1. Human Polyclonal Phospholipase C gamma 2 Primary Antibody für IF, WB - ABIN197402 : Kim, Sekiya, Poulin, Bae, Rhee: Mechanism of B-cell receptor-induced phosphorylation and activation of phospholipase C-gamma2. in Molecular and cellular biology 2004 (PubMed)
    Zeige alle 4 Referenzen für ABIN197402

  2. Human Polyclonal Phospholipase C gamma 2 Primary Antibody für IF, IHC (p) - ABIN319401 : Smrcka, Hepler, Brown, Sternweis: Regulation of polyphosphoinositide-specific phospholipase C activity by purified Gq. in Science (New York, N.Y.) 1991 (PubMed)
    Zeige alle 4 Referenzen für ABIN319401

  3. Human Polyclonal Phospholipase C gamma 2 Primary Antibody für IF, WB - ABIN196906 : Humphries, Dangelmaier, Sommer, Kipp, Kato, Griffith, Bakman, Turk, Daniel, Rawlings: Tec kinases mediate sustained calcium influx via site-specific tyrosine phosphorylation of the phospholipase Cgamma Src homology 2-Src homology 3 linker. in The Journal of biological chemistry 2004 (PubMed)
    Zeige alle 4 Referenzen für ABIN196906

  4. Human Polyclonal Phospholipase C gamma 2 Primary Antibody für IHC (p) - ABIN319283 : Mattaj: A binding consensus: RNA-protein interactions in splicing, snRNPs, and sex. in Cell 1989 (PubMed)
    Zeige alle 3 Referenzen für ABIN319283

  5. Human Polyclonal Phospholipase C gamma 2 Primary Antibody für IF (p), IHC (p) - ABIN700375 : Diaz-Flores, Goldschmidt, Depeille, Ng, Akutagawa, Krisman, Crone, Burgess, Williams, Houseman, Shokat, Sampath, Bollag, Roose, Braun, Shannon: PLC-? and PI3K link cytokines to ERK activation in hematopoietic cells with normal and oncogenic Kras. in Science signaling 2013 (PubMed)

  6. Human Polyclonal Phospholipase C gamma 2 Primary Antibody für IHC, ELISA - ABIN1531237 : Martin, Han, Gordon, Terry, Prabhakar, She, Xie, Hellsten, Chan, Altherr, Couronne, Aerts, Bajorek, Black, Blumer, Branscomb, Brown, Bruno, Buckingham, Callen, Campbell, Campbell, Campbell, Caoile et al.: The sequence and analysis of duplication-rich human chromosome 16. ... in Nature 2004 (PubMed)

Weitere Antikörper gegen Phospholipase C gamma 2 Interaktionspartner

Mouse (Murine) Phospholipase C gamma 2 (PLCG2) Interaktionspartner

  1. Results show that mice with the mutated Plcg2 gene were less prone to transformation into MALT lymphomas as a result of elevated Treg numbers, and decrease of pro-inflammatory cytokines.

  2. PLCgamma2 in clear cells plays an essential role in luminal expansion of the epididymis during the prepubertal period in mice

  3. platelet activation through GPVI (zeige GP6 Antikörper) and alphaIIbbeta3 utilizes PLCgamma2 because PLCgamma1 (zeige PLCG1 Antikörper) levels are insufficient to support responsiveness, but that PLCgamma1 (zeige PLCG1 Antikörper) can restore responsiveness if expressed at levels normally achieved by PLCgamma2.

  4. amarogentin prevents platelet activation through the inhibition of PLC (zeige HSPG2 Antikörper) gamma2-PKC (zeige PKC Antikörper) cascade and MAPK (zeige MAPK1 Antikörper) pathway

  5. PLCgamma2 and protein kinase C (zeige PKC Antikörper) are important upstream signals that regulate myelopoiesis through cytokines.

  6. inflammatory osteolysis can be abrogated by treatment with a molecule composed of the tandem SH2 (zeige MYO15 Antikörper) domains of PLCgamma2.

  7. down-regulation of PLCgamma2-beta-catenin (zeige CTNNB1 Antikörper) pathway occurs in mice and humans and leads to myeloid-derived suppressor cells-mediated tumor expansion.

  8. a novel role of the PLCgamma2-IP(3)-Ca(2 (zeige CA2 Antikörper)+) cascade in the LPS (zeige TLR4 Antikörper)-induced innate immune response pathway where release of intracellular Ca(2 (zeige CA2 Antikörper)+) mediates TLR4 (zeige TLR4 Antikörper) trafficking and subsequent activation of IRF3 (zeige IRF3 Antikörper).

  9. VapB (zeige VAPB Antikörper) positively regulates RANKL (zeige TNFSF11 Antikörper)-mediated osteoclastogenesis via PLCgamma2-Ca(2 (zeige CA2 Antikörper)+)-NFAT (zeige NFATC1 Antikörper) signaling

  10. PLCgamma2 deficiency impairs Dectin-2 (zeige CLEC6A Antikörper)-induced NF-kappaB (zeige NFKB1 Antikörper) and MAPK (zeige MAPK1 Antikörper) activation in response to fungal infection

Human Phospholipase C gamma 2 (PLCG2) Interaktionspartner

  1. R665W and L845F be referred to as allomorphic rather than hypermorphic mutations of PLCG2 Rerouting of the transmembrane signals emanating from BCR (zeige BCR Antikörper) and converging on PLCgamma2 through Rac (zeige AKT1 Antikörper) in ibrutinib-resistant CLL cells may provide novel drug treatment strategies to overcome ibrutinib resistance mediated by PLCG2 mutations or to prevent its development in ibrutinib-treated CLL patients.

  2. Data show that phospholipase Cgamma2 (PLCgamma2) is strongly expressed in B cell non-Hodgkin lymphoma and especially in a large subset of Diffuse large B-cell lymphoma (DLBCL).

  3. Characterization of the effect of missense point-mutation at R665W in PLCG2 on signaling mechanisms of ibrutinib resistance in chronic lymphocytic leukemia cells.

  4. amarogentin prevents platelet activation through the inhibition of PLC (zeige HSPG2 Antikörper) gamma2-PKC (zeige PRRT2 Antikörper) cascade and MAPK (zeige MAPK1 Antikörper) pathway

  5. PLCG2 missense mutation is a risk factor in the development of steroid sensitive nephrotic syndrome in childhood.

  6. The autoinhibitory C-terminal SH2 domain of phospholipase C (zeige PLC Antikörper)-gamma2 stabilizes B cell receptor signalosome assembly.

  7. The relationship between upstream tyrosine kinase (zeige TXK Antikörper) SYK (zeige SYK Antikörper) and its target, PLCgamma2, is maximally predictive and sufficient to distinguish chronic lymphocytic leukemia from healthy controls.

  8. Single-nucleotide polymorphisms in PLCG2 gene is associated with breast cancer risk after menopausal hormone replacement therapy.

  9. identified three distinct mutations in PLCgamma2 in two patients resistant to ibrutinib

  10. early Ca(2 (zeige CA2 Antikörper)+) fluxing provides feed-forward signal amplification by promoting anchoring of the PLCgamma2 C2 domain to phospho-SLP65 (zeige BLNK Antikörper).

Phospholipase C gamma 2 (PLCG2) Antigen-Profil

Beschreibung des Gens

The protein encoded by this gene is a transmembrane signaling enzyme that catalyzes the conversion of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate to 1D-myo-inositol 1,4,5-trisphosphate (IP3) and diacylglycerol (DAG), using calcium as a cofactor. IP3 and DAG are second messenger molecules important for transmitting signals from growth factor receptors and immune system receptors across the cell membrane.

Alternative names and synonyms associated with Phospholipase C gamma 2 (PLCG2)

  • phospholipase C, gamma 2 (Plcg2) Antikörper
  • phospholipase C, gamma 2 (phosphatidylinositol-specific) (PLCG2) Antikörper
  • phospholipase C, gamma 2 (phosphatidylinositol-specific) (Plcg2) Antikörper
  • APLAID Antikörper
  • FCAS3 Antikörper
  • Plcg-2 Antikörper
  • PLCgamma2 Antikörper

Bezeichner auf Proteinebene für PLCG2

1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 , 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma-2 , PLC-gamma-2 , phosphoinositide phospholipase C-gamma-2 , phospholipase C-gamma-2 , PLC-IV , phosphoinositide phospholipase C , phospholipase C-IV , phosphatidylinositol-specific phospholipase C

GENE ID SPEZIES
234779 Mus musculus
29337 Rattus norvegicus
5336 Homo sapiens
489692 Canis lupus familiaris
100518663 Sus scrofa
281988 Bos taurus
415805 Gallus gallus
100726796 Cavia porcellus
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