anti-CD226 (CD226) Antikörper

anti-CD226 Molecule Antikörper (CD226)
Auf finden Sie aktuell 210 CD226 Molecule (CD226) Antikörper von 22 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen CD226 Proteine (24) und CD226 Kits (14) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 263 CD226 Produkte verfügbar.
BC051526, cd226, DNAM-1, DNAM1, PTA1, TLiSA1, zgc:158817
Alle Antikörper anzeigen Gen GeneID UniProt
CD226 225825 Q8K4F0
CD226 10666 Q15762
CD226 307199  

Alle Spezies anzeigen

Weitere Synonyme anzeigen

Meistgesuchte Reaktivitäten zu anti-CD226 (CD226) Antikörper

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anti-Mouse (Murine) CD226 Antikörper:

anti-Human CD226 Antikörper:

anti-Rat (Rattus) CD226 Antikörper:

Alle verfügbaren anti-CD226 Antikörper

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Am meisten referenzierte anti-CD226 Antikörper

  1. Human Monoclonal CD226 Primary Antibody für Func, FACS - ABIN119797 : Kojima, Kanada, Shimizu, Kasama, Shibuya, Nakauchi, Nagasawa, Shibuya: CD226 mediates platelet and megakaryocytic cell adhesion to vascular endothelial cells. in The Journal of biological chemistry 2003 (PubMed)
    Zeige alle 3 Referenzen für 119797

  2. Human Monoclonal CD226 Primary Antibody für FACS - ABIN119800 : Shibuya, Campbell, Hannum, Yssel, Franz-Bacon, McClanahan, Kitamura, Nicholl, Sutherland, Lanier, Phillips: DNAM-1, a novel adhesion molecule involved in the cytolytic function of T lymphocytes. in Immunity 1996 (PubMed)
    Zeige alle 3 Referenzen für 119800

  3. Human Monoclonal CD226 Primary Antibody für FACS - ABIN119796 : Shibuya, Lanier, Phillips: Protein kinase C is involved in the regulation of both signaling and adhesion mediated by DNAX accessory molecule-1 receptor. in Journal of immunology (Baltimore, Md. : 1950) 1998 (PubMed)
    Zeige alle 3 Referenzen für 119796

  4. Human Monoclonal CD226 Primary Antibody für FACS - ABIN4896039 : Liu, Qian, Chen, Xu, Gao, Zhang, Zhang, Qi, Gao, Yan: Crystal structure of cell adhesion molecule nectin-2/CD112 and its binding to immune receptor DNAM-1/CD226. in Journal of immunology (Baltimore, Md. : 1950) 2012 (PubMed)

  5. Human Monoclonal CD226 Primary Antibody für FACS - ABIN4896040 : Brunetta, Fogli, Varchetta, Bozzo, Hudspeth, Marcenaro, Moretta, Mavilio: The decreased expression of Siglec-7 represents an early marker of dysfunctional natural killer-cell subsets associated with high levels of HIV-1 viremia. in Blood 2009 (PubMed)

  6. Human Monoclonal CD226 Primary Antibody für FACS - ABIN1449202 : Shibuya, Shirakawa, Kameyama, Honda, Tahara-Hanaoka, Miyamoto, Onodera, Sumida, Nakauchi, Miyoshi, Shibuya: CD226 (DNAM-1) is involved in lymphocyte function-associated antigen 1 costimulatory signal for naive T cell differentiation and proliferation. in The Journal of experimental medicine 2003 (PubMed)

Weitere Antikörper gegen CD226 Interaktionspartner

Mouse (Murine) CD226 Molecule (CD226) Interaktionspartner

  1. Blocking CD226 inhibited NK cell-mediated cytotoxicity of the GM-CSF (zeige CSF2 Antikörper)-stimulated Flt3 ligand (zeige FLT3LG Antikörper) conventional dendritic cells. The CD226(+)NKG2A (zeige KLRC1 Antikörper)(-) subset of NK cells was better at targeting GM-CSF (zeige CSF2 Antikörper)-stimulated Flt3 ligand (zeige FLT3LG Antikörper) conventional dendritic cells. CD155 (zeige PVR Antikörper), a known ligand for CD226, could also act as an inhibitor of NK cell-mediated lysis, as dendritic cells lacking CD155 (zeige PVR Antikörper) were more sensitive to NK cell-mediated lysis.

  2. inflammatory monocytes, together with NK cells, are essential in the early control of CMV through the DNAM-1-PVR (zeige PVRL2 Antikörper) pathway.

  3. Data show that CD155 (zeige PVR Antikörper) protein/CD226 antigen mainly mediates the interaction between NK cells and leukemic cells in acute myeloid leukemia (zeige BCL11A Antikörper). To investigate the interaction between leukemic cells

  4. absence of either CD155 (zeige PVR Antikörper) or CD226 in BALB/c mice causes a profound shift in the Natural Killer T-Cells subtype composition in thymus, expanding the frequency and numbers of iNKT1 cells at the expense of iNKT2 cells, as well as iNKT17 cells.

  5. our results suggest a limited role for DNAM-1 in solid allograft rejection. Blocking DNAM-1 is not sufficient to prevent allograft rejection and might be relevant only in combination with additional inhibitors of costimulation.

  6. we propose that expression of DNAM-1 on inflammatory monocytes are evolutionally conserved and act as an adhesion molecule (zeige NCAM1 Antikörper) on blood inflammatory monocytes.

  7. Data indicate that DNAM-1 (CD226) signaling was required to enhance cytotoxicity.

  8. Regulatory T cells derived (zeige CD4 Antikörper)from Cd226-deficient mice showed similarly reduced inhibitory activity, eventually resulting in an exacerbated disease course of experimental autoimmune encephalomyelitis.

  9. CD226 limits spontaneous multiple myeloma development in Vk*MYC (zeige MYC Antikörper) transgenic mice. This is mediated both by NK and CD8 (zeige CD8A Antikörper)+ T cells through perforin (zeige PRF1 Antikörper) and IFN-gamma (zeige IFNG Antikörper) pathways. It also is needed for cyclophosphamide and bortezomib treatment effectiveness.

  10. Findings suggest that TIGIT (zeige TIGIT Antikörper) is a key checkpoint inhibitor of chronic antiviral and antitumor responses through impairing CD226 function when disrupting its homodimerization.

Human CD226 Molecule (CD226) Interaktionspartner

  1. cumulative incidences of acute graft-versus-host disease in patients with high maximal serum levels of sDNAM-1 (>/=30 pM) in the 7 days before allogeneic hematopoietic stem cell transplantation were significantly higher than those in patients with low maximal serum levels of sDNAM-1 in the same period. Our data suggest sDNAM-1 is potentially a unique candidate as a predictive biomarker for the development of acute GVHD.

  2. Our results support an important association of rs4810485 in CD40 (zeige CD40 Antikörper) gene and rs763361 in CD226 gene polymorphism, combined effect of rs4810485 and rs763361 with increased risk of systemic lupus erythematosus.

  3. our results support and explain the mechanism behind the recently reported finding that in EOC, NK-cell recognition and killing of tumor cells was mainly dependent on DNAM-1 signaling while the contribution of the NKG2D (zeige KLRK1 Antikörper) receptor-ligand pathway was complementary and uncertain.

  4. CD226 rs763361 polymorphism was significantly associated with susceptibility to T1D.

  5. Age and CMV serostatus influence the expression of NKp30 (zeige NCR3 Antikörper), NKp46 (zeige NCR1 Antikörper) and DNAM-1 activating receptors on resting and IL-2 (zeige IL2 Antikörper) activated natural killer cells.

  6. we propose that expression of DNAM-1 on inflammatory monocytes are evolutionally conserved and act as an adhesion molecule (zeige NCAM1 Antikörper) on blood inflammatory monocytes.

  7. DNAM-1 ligands CD112 (zeige PVRL2 Antikörper) and CD155 (zeige PVR Antikörper) as well as the NKG2D (zeige KLRK1 Antikörper) ligands MICA (zeige MICA Antikörper) and MICB (zeige MICB Antikörper) were expressed on the hiPSC lines

  8. The CD226 gene has been identified as novel association with JIA, and a SNP near CD28 (zeige CD28 Antikörper) as a suggestive association.

  9. Effector and regulatory CD4 (zeige CD4 Antikörper)+ memory T cells of healthy individuals carrying the predisposing CD226 variant showed, in comparison to carriers of the protective variant, reduced surface expression of CD226 and impaired induction of CD226 after stimulation.

  10. The present study provides evidence that regulation of the PVR/CD155 (zeige PVR Antikörper) DNAM-1 ligand expression by nitric oxide may represent an additional immune-mediated mechanism and supports the anti-myeloma activity of nitric oxide donors.

CD226 Antigen-Profil

Beschreibung des Gens

This gene encodes a glycoprotein expressed on the surface of NK cells, platelets, monocytes and a subset of T cells. It is a member of the Ig-superfamily containing 2 Ig-like domains of the V-set. The protein mediates cellular adhesion of platelets and megakaryocytic cells to vascular endothelial cells. The protein also plays a role in megakaryocytic cell maturation.

Alternative names and synonyms associated with CD226

  • CD226 molecule (CD226) Antikörper
  • CD226 antigen (cd226) Antikörper
  • CD226 molecule (cd226) Antikörper
  • CD226 antigen (Cd226) Antikörper
  • CD226 molecule (Cd226) Antikörper
  • BC051526 Antikörper
  • cd226 Antikörper
  • DNAM-1 Antikörper
  • DNAM1 Antikörper
  • PTA1 Antikörper
  • TLiSA1 Antikörper
  • zgc:158817 Antikörper

Bezeichner auf Proteinebene für anti-CD226 Molecule (CD226) Antikörper

CD226 antigen , CD226 molecule , platelet and T cell activation antigen 1 , platelet and T-cell activation antigen 1 , DNAX accessory molecule 1 , DNAX accessory molecule-1 , T lineage-specific activation antigen 1 antigen , adhesion glycoprotein

468577 Pan troglodytes
609196 Canis lupus familiaris
100194885 Salmo salar
791164 Danio rerio
772097 Gallus gallus
100579250 Nomascus leucogenys
225825 Mus musculus
10666 Homo sapiens
615496 Bos taurus
307199 Rattus norvegicus
703878 Macaca mulatta
Ausgewählte Anbieter für anti-CD226 (CD226) Antikörper
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