SMG Protein, Sm-G Protein, 2810024K17Rik Protein, AL022803 Protein, sm-G Protein, snRNP-G Protein, MGC188855 Protein, SNRPG Protein, snrpg Protein, MGC154809 Protein, SmG Protein, small nuclear ribonucleoprotein polypeptide G Protein, small nuclear ribonucleoprotein polypeptide G S homeolog Protein, small nuclear ribonucleoprotein G Protein, SNRPG Protein, Snrpg Protein, snrpg Protein, snrpg.S Protein, PY07229 Protein, SMP2 Protein, LOC107131494 Protein
Hintergrund
Small nuclear ribonucleoprotein polypeptide G, also known as SNRPG, belongs to the snRNP Sm proteins family. There are at least seven isoforms, B/B, E, F, G, D1, D2, and D3. This class of common proteins plays an essential role in the biogenesis of the snRNPs. The genes encoding human Sm G map to chromosomes 2. In addition, these proteins represent the major targets for the so-called anti-Sm auto-antibodies which are diagnostic for systemic lupus erythematosus (SLE). One class of these autoantibodies reacts specifically with native Sm E-F-G complexes. Recombinant human SNRPG protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: Small nuclear ribonucleoprotein polypeptide G, Sm-G, SMG. NCBI no.: NP_003087