zgc:73118 Protein, C530046K05Rik Protein, D11Ertd539e Protein, EMegR4 Protein, Sinbp1 Protein, 2HOR0202 Protein, SAP18P Protein, Sin3A-associated protein Protein, Sin3-associated polypeptide 18 Protein, Sin3A associated protein 18 Protein, Sin3A associated protein 18kDa S homeolog Protein, sap18 Protein, Sap18 Protein, sap18.S Protein, SAP18 Protein
Hintergrund
SAP18, also known as Sin3A-associated protein, is component of the histone deacetylase complex that plays an important role in the regulation of eukaryotic gene expression. This protein directly interacts with SIN3 and enhances SIN3-mediated transcriptional repression when tethered to the promoter. It also has been shown to play a key role in gene-specific recruitment of the HDAC complex by a number of transcription factors including Gli, GAGA, and Bicoid. Recombinant SAP18 protein was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: Sin3A-associated protein, 2HOR0202, SAP18P, SAP18, Sin3A-associated protein, 18kDa Histone deacetylase complex subunit SAP18, Sin3-associated polypeptide p18. NCBI no.: NP_005861