ZYX Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag)

Produktnummer ABIN2736195

Produktdetails

Target: ZYX (Zyxin (ZYX))

Protein-Typ: Recombinant

Proteineigenschaft: Transcript Variant 2

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses ZYX Protein ist gelabelt mit Myc-DYKDDDDK Tag.

Applikation: Antibody Production (AbP), Standard (STD)

Produktmerkmale:

• Recombinant human Zyxin (transcript variant 2) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Reinheit: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Anwendungsinformationen

Applikationshinweise: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Kommentare:

The tag is located at the C-terminal.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Lagerung: -80 °C

Informationen zur Lagerung: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Antigendetails

Target: ZYX (Zyxin (ZYX))

Andere Bezeichnung: Zyxin (ZYX Produkte)

Synonyme: BcDNA:LD06023 Protein, CG32018 Protein, DLim-1 Protein, DmLIM-1 Protein, Dmel\\CG32018 Protein, Lim102EF Protein, ZYX102 Protein, Zyx102 Protein, Zyx102EF Protein, lim Protein, zyx102 Protein, zyxin Protein, zgc:171680 Protein, ZYX Protein, zyx Protein, MGC145270 Protein, ESP-2 Protein, HED-2 Protein, 9530098H06Rik Protein, R75157 Protein, Zyxin Protein, zyxin Protein, zyxin S homeolog Protein, zyx-1 Protein, Zyx Protein, zyx Protein, ZYX Protein, EDI_201420 Protein, zyx.S Protein

Hintergrund: Focal adhesions are actin-rich structures that enable cells to adhere to the extracellular matrix and at which protein complexes involved in signal transduction assemble. Zyxin is a zinc-binding phosphoprotein that concentrates at focal adhesions and along the actin cytoskeleton. Zyxin has an N-terminal proline-rich domain and three LIM domains in its C-terminal half. The proline-rich domain may interact with SH3 domains of proteins involved in signal transduction pathways while the LIM domains are likely involved in protein-protein binding. Zyxin may function as a messenger in the signal transduction pathway that mediates adhesion-stimulated changes in gene expression and may modulate the cytoskeletal organization of actin bundles. Alternative splicing results in multiple transcript variants that encode the same isoform.

Molekulargewicht: 61.1 kDa

NCBI Accession: NP_001010972