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DLAT Protein (Myc-DYKDDDDK Tag)

DLAT Spezies: Human Wirt: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Produktnummer ABIN2719517
  • Target Alle DLAT Proteine anzeigen
    DLAT (Dihydrolipoyl Transacetylase (DLAT))
    Protein-Typ
    Recombinant
    Spezies
    • 6
    • 3
    • 1
    Human
    Quelle
    • 5
    • 2
    • 1
    • 1
    HEK-293 Cells
    Aufreinigungstag / Konjugat
    Dieses DLAT Protein ist gelabelt mit Myc-DYKDDDDK Tag.
    Applikation
    Antibody Production (AbP), Standard (STD)
    Produktmerkmale
    • Recombinant human DLAT / DLTA protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    Reinheit
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product DLAT Protein
  • Applikationshinweise
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Kommentare

    The tag is located at the C-terminal.

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    50 μg/mL
    Buffer
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    Lagerung
    -80 °C
    Informationen zur Lagerung
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target
    DLAT (Dihydrolipoyl Transacetylase (DLAT))
    Andere Bezeichnung
    Dlat,dlta (DLAT Produkte)
    Synonyme
    DLAT Protein, Dmel\\CG5261 Protein, EP(2)0816 Protein, EP816 Protein, anon-WO0118547.121 Protein, DLTA Protein, PDC-E2 Protein, PDCE2 Protein, wu:fc14f10 Protein, wu:fc21f08 Protein, wu:fc86g11 Protein, wu:fj57d06 Protein, 6332404G05Rik Protein, midline uncoordinated Protein, dihydrolipoamide S-acetyltransferase L homeolog Protein, dihydrolipoamide S-acetyltransferase Protein, dihydrolipoamide S-acetyltransferase (E2 component of pyruvate dehydrogenase complex) Protein, muc Protein, dlat.L Protein, DLAT Protein, Dlat Protein, dlat Protein
    Hintergrund
    This gene encodes component E2 of the multi-enzyme pyruvate dehydrogenase complex (PDC). PDC resides in the inner mitochondrial membrane and catalyzes the conversion of pyruvate to acetyl coenzyme A. The protein product of this gene, dihydrolipoamide acetyltransferase, accepts acetyl groups formed by the oxidative decarboxylation of pyruvate and transfers them to coenzyme A. Dihydrolipoamide acetyltransferase is the antigen for antimitochondrial antibodies. These autoantibodies are present in nearly 95 % of patients with the autoimmune liver disease primary biliary cirrhosis (PBC). In PBC, activated T lymphocytes attack and destroy epithelial cells in the bile duct where this protein is abnormally distributed and overexpressed. PBC enventually leads to cirrhosis and liver failure. Mutations in this gene are also a cause of pyruvate dehydrogenase E2 deficiency which causes primary lactic acidosis in infancy and early childhood.[provided by RefSeq, Oct 2009].
    Molekulargewicht
    59.6 kDa
    NCBI Accession
    NP_001922
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