CENPM Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)

Produktnummer ABIN2713909

Produktdetails

Target: CENPM (Centromere Protein M (CENPM))

Protein-Typ: Recombinant

Proteineigenschaft: Transcript Variant 1

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses CENPM Protein ist gelabelt mit Myc-DYKDDDDK Tag.

Applikation: Antibody Production (AbP), Standard (STD)

Produktmerkmale:

• Recombinant human CENP-M (transcript variant 1) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Reinheit: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Anwendungsinformationen

Applikationshinweise: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Kommentare:

The tag is located at the C-terminal.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Lagerung: -80 °C

Informationen zur Lagerung: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Antigendetails

Target: CENPM (Centromere Protein M (CENPM))

Andere Bezeichnung: Cenp-M (CENPM Produkte)

Synonyme: C22orf18 Protein, CENP-M Protein, PANE1 Protein, bK250D10.2 Protein, 2610019I03Rik Protein, AI853711 Protein, Pane1 Protein, RGD1307309 Protein, centromere protein M Protein, centromere protein M L homeolog Protein, Centromere protein M Protein, centromere protein M pseudogene Protein, CENPM Protein, Cenpm Protein, cenpm Protein, cenpm.L Protein, LOC100353362 Protein

Hintergrund: The protein encoded by this gene is an inner protein of the kinetochore, the multi-protein complex that binds spindle microtubules to regulate chromosome segregation during cell division. It belongs to the constitutive centromere-associated network protein group, whose members interact with outer kinetochore proteins and help to maintain centromere identity at each cell division cycle. The protein is structurally related to GTPases but cannot bind guanosine triphosphate. A point mutation that affects interaction with another constitutive centromere-associated network protein, CENP-I, impairs kinetochore assembly and chromosome alignment, suggesting that it is required for kinetochore formation. Alternative splicing results in multiple transcript variants.

Molekulargewicht: 19.6 kDa

NCBI Accession: NP_076958