Retinol Binding Protein 4, Plasma (RBP4) (AA 19-201) protein (DYKDDDDK Tag)

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Proteinname
  • rbp4
  • MGC54038
  • srbp
  • 2310002G05Rik
  • 2610028L19Rik
  • HSRBP4
  • RBP4
  • RBP
  • RNBP
  • RDCCAS
  • Rbp-4
  • RBPA
  • PRBP
  • retinol binding protein 4, plasma
  • polymerase (RNA) II (DNA directed) polypeptide D
  • renin binding protein
  • rbp4
  • Polr2d
  • RENBP
  • RBP4
  • Rbp4
Proteineigenschaft
AA 19-201
24
8
6
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Spezies
Ratte (Rattus)
39
11
8
4
3
2
2
2
1
1
1
1
1
Quelle
HEK-293 Cells
25
12
9
7
6
5
2
2
1
Protein-Typ
Recombinant
Aufreinigungstag / Konjugat
Dieses RBP4 Protein ist gelabelt mit DYKDDDDK Tag.
Applikation
SDS-PAGE (SDS)
Optionen
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Kreuzreaktivität Ratte (Rattus)
Produktmerkmale Rat RBP4 (aa 19-201) is fused at the N-terminus to a FLAG®-tag.
Reinheit >90 % (SDS-PAGE)
Sterilität 0.2 μm filtered
Endotoxin-Niveau <0.1EU/μg purified protein (LAL test, Lonza).
Hintergrund Retinol binding protein 4 (RBP4, RBP) is a 21 kDa secreted protein, a member of the lipocalin family and is known as the primary transporter of retinol (vitamin A) to tissues. A recent report revealed RBP4 as an adipokine linking glucose transporter 4 (GLUT4) suppression in adipose tissue to insulin. Elevated human and mouse serum RBP4 levels are associated with insulin resistance and its severity, obesity, and certain components of metabolic syndrome. Furthermore, human serum RBP4 levels are closely related to renal function.
Molekulargewicht ~23kDa (SDS-PAGE)
UniProt P04916
Forschungsgebiet Cardiovascular, Atherosclerosis, Metabolism, Hormones, Cytokines
Pathways Regulatorische RNA Pathways, Positive Regulation of Peptide Hormone Secretion, Carbohydrate Homeostasis, Production of Molecular Mediator of Immune Response
Applikationshinweise Optimal working dilution should be determined by the investigator.
Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Buffer 0.2μm-filtered solution in PBS, pH 7.2.
Lagerung 4 °C,-20 °C
Informationen zur Lagerung Short Term Storage: +4°C
Long Term Storage: -20°C
Working aliquots are stable for up to 3 months when stored at -20°C.
Haltbarkeit 3 months
Produkt verwendet in: Casillas-Ramírez, Alfany-Fernández, Massip-Salcedo, Juan, Planas, Serafín, Pallàs, Rimola, Rodés, Peralta: "Retinol-binding protein 4 and peroxisome proliferator-activated receptor-? in steatotic liver transplantation." in: The Journal of pharmacology and experimental therapeutics, Vol. 338, Issue 1, pp. 143-53, 2011 (PubMed).