Chemokine (C-C Motif) Ligand 1 (CCL1) (AA 24-96) Protein

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Proteinname
  • I-309
  • P500
  • SCYA1
  • SISe
  • TCA3
  • BF534335
  • Scya1
  • Tca-3
  • CCLi6
  • chemokine
  • chemokine (C-C motif) ligand 1
  • CCL1
  • Ccl1
Proteineigenschaft
AA 24-96
9
3
1
1
1
1
Spezies
Human
29
4
Quelle
Escherichia coli (E. coli)
18
2
2
2
1
1
Protein-Typ
Recombinant
Applikation
Functional Studies (Func)
Optionen
Hersteller
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Verwendungszweck Recombinant Human C-C Motif Chemokine 1/CCL1
Sequenz MKSMQVPFSR CCFSFAEQEI PLRAILCYRN TSSICSNEGL IFKLKRGKEA CALDTVGWVQ RHRKMLRHCP SKRK
Produktmerkmale Recombinant Human C-C Motif Chemokine 1/CCL1 is produced with our E. coli expression system. The target protein is expressed with sequence (K24-K96) of Human CCL1.
Reinheit > 95 % as determined by reducing SDS-PAGE.
Sterilität 0.2 μm filtered
Endotoxin-Niveau Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
Hintergrund Chemokine (C-C Motif) Ligand 1 (CCL1) is a small glycoprotein secreted by activated T cells, which play a central role during immunoregulatory and inflammaion processes. Human CCL1 has been assumed to be a homologue of the mouse TCA3. While the two proteins share only approximately 42% amino acid sequence identity, both chemokines contain an extra pair of cysteine residues not found in most other chemokines. CCL1 attracts monocytes, NK cells, and immature B cells and dendritic cells by interacting with cell surface chemokine receptor CCR8. CCL1 is identified as a potent inhibitor of HIV-1 envelope-mediated cell-cell fusion and virus infection.
Alternative Names: C-C Motif Chemokine 1, Small-Inducible Cytokine A1, T Lymphocyte-Secreted Protein I-309, CCL1, SCYA1
Molekulargewicht 8.62 kDa
UniProt P22362
Beschränkungen Nur für Forschungszwecke einsetzbar
Format Lyophilized
Rekonstitution It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
Buffer Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.2.
Handhabung Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
Lagerung 4 °C/-20 °C/-80 °C
Informationen zur Lagerung Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Haltbarkeit 3 months
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