PTTG1IP Proteine (PTTG1IP)

Bezeichnung:
Pituitary Tumor-Transforming 1 Interacting Protein Proteine (PTTG1IP)
Auf www.antikoerper-online.de finden Sie aktuell 6 Pituitary Tumor-Transforming 1 Interacting Protein (PTTG1IP) Proteine von 4 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen PTTG1IP Antikörper (24) und PTTG1IP Kits (21) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 54 PTTG1IP Produkte verfügbar.
Synonyme:
1810010L20Rik, AI314311, AU018448, C21orf1, C21orf3, C79540, PBF
alle Proteine anzeigen Gen GeneID UniProt
PTTG1IP 108705 Q8R143
Ratte PTTG1IP PTTG1IP 365548 Q6P767
PTTG1IP 754 P53801

Weitere Synonyme anzeigen

PTTG1IP Proteine (PTTG1IP) nach Spezies

Wählen Sie die gewünschte Spezies

Weitere Proteine zu PTTG1IP Interaktionspartnern

Mouse (Murine) Pituitary Tumor-Transforming 1 Interacting Protein (PTTG1IP) Interaktionspartner

  1. protooncogene PBF is a negative regulator of p53 (zeige TP53 Proteine) function in thyroid tumorigenesis, in which PBF is generally overexpressed and p53 (zeige TP53 Proteine) mutations are rare compared with other tumor types

Human Pituitary Tumor-Transforming 1 Interacting Protein (PTTG1IP) Interaktionspartner

  1. Findings indicate that PBF and PTTG (zeige PTTG1 Proteine) have a critical role in promoting thyroid cancer that is predictive of poorer patient outcome.

  2. Unique role for PBF in regulating CTTN (zeige CTTN Proteine) function to promote endocrine cell invasion and migration.

  3. these results demonstrate an emerging role for PBF in colorectal tumorigenesis through regulating p53 (zeige TP53 Proteine) activity, with implications for PBF as a prognostic indicator for invasive tumors.

  4. These findings indicate that miR (zeige MLXIP Proteine)-584 suppresses glioma cell growth by negatively regulating the expression of PTTG1IP, suggesting that miR (zeige MLXIP Proteine)-584 has a tumor suppressive role in human glioma pathogenesis.

  5. protooncogene PBF is a negative regulator of p53 (zeige TP53 Proteine) function in thyroid tumorigenesis, in which PBF is generally overexpressed and p53 (zeige TP53 Proteine) mutations are rare compared with other tumor types

  6. Data from mutant recombinant proteins suggest that proto-oncogene PBF is a phosphoprotein and highlight importance of tyrosine residue Y174 in both endocytosis of PBF and its interaction/co-localization with NIS/SLC5A5 (sodium-iodide symporter).

  7. PBF expression may be a promising biomarker for prognostic and therapeutic purposes in papillary thyroid carcinoma patients.

  8. Authors identified pituitary tumor-transforming gene 1 (PTTG1 (zeige PTTG1 Proteine)) binding factor (PBF) as a target of miR (zeige MLXIP Proteine)-122 and demonstrated that hepatitis B virus replication causes an obvious increase in PBF levels.

  9. The present study provides the first epidemiological evidence that functional regulatory variants of PTTG1IP were associated with the risk of ER-positive breast cancer, further supporting its relevance as one proto-oncogene (zeige RAB1A Proteine) in breast cancer.

  10. overexpression of PBF causes thyroid cell proliferation, macrofollicular lesions, and hyperplasia, as well as repression of the critical therapeutic route for radioiodide uptake

PTTG1IP Protein Überblick

Protein Überblick

The encoded protein, which directly binds to pituitary tumor-transforming gene 1 protein (PTTG1), facilitates the nuclear translocation of PTTG1 and potentiates the transcriptional activation of basic fibroblast growth factor by PTTG1. The gene product localizes to both the cytoplasm and nucleus. Its NLS is required for its own nuclear localization, the nuclear localization of PTTG1, and its interaction with PTTG1.

Alternative names and synonyms associated with PTTG1IP

  • pituitary tumor-transforming 1 interacting protein (Pttg1ip)
  • pituitary tumor-transforming 1 interacting protein (PTTG1IP)
  • pituitary tumor-transforming gene 1 protein-interacting protein-like (LOC100624320)
  • 1810010L20Rik Protein
  • AI314311 Protein
  • AU018448 Protein
  • C21orf1 Protein
  • C21orf3 Protein
  • C79540 Protein
  • PBF Protein

Bezeichner auf Proteinebene für PTTG1IP

PBF , PTTG-binding factor , pituitary tumor-transforming gene 1 protein-interacting protein , pituitary tumor-transforming gene protein-binding factor

GENE ID SPEZIES
108705 Mus musculus
365548 Rattus norvegicus
754 Homo sapiens
100717897 Cavia porcellus
617245 Bos taurus
420545 Gallus gallus
100174140 Pongo abelii
100624320 Sus scrofa
Ausgewählte Anbieter für PTTG1IP Proteine (PTTG1IP)
Haben Sie etwas anderes gesucht?