Pleckstrin Homology Domain Interacting Protein Proteine (PHIP)

Bezeichnung:
Pleckstrin Homology Domain Interacting Protein Proteine (PHIP)
Auf www.antikoerper-online.de finden Sie aktuell 2 Pleckstrin Homology Domain Interacting Protein (PHIP) Proteine von 2 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen Pleckstrin Homology Domain Interacting Protein Antikörper (18) und Pleckstrin Homology Domain Interacting Protein Kits (2) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 22 Pleckstrin Homology Domain Interacting Protein Produkte verfügbar.
Synonyme:
2810004D21Rik, 4632404O06Rik, BRWD2, DCAF14, Ndrp, PHIP, Wdr11
alle Proteine anzeigen Gen GeneID UniProt
PHIP 55023 Q8WWQ0
Maus PHIP PHIP 83946  

Weitere Synonyme anzeigen

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Human Pleckstrin Homology Domain Interacting Protein (PHIP) Interaktionspartner

  1. These results provide further support for PHIP as a molecular prognostic marker of melanoma, and reveal a significant linkage between PHIP levels and ulceration.

  2. The PHIP gene resides on 6q14.1, and although 6q loss has been observed in melanoma, the PHIP locus was preserved in melanoma cell lines and patient samples, and its overexpression was an independent adverse predictor of survival in melanoma patients.

Mouse (Murine) Pleckstrin Homology Domain Interacting Protein (PHIP) Interaktionspartner

  1. Systemic, plasmid-based shRNA targeting of Phip inhibited the metastatic progression of melanoma, whereas stable suppression of Phip in melanoma cell lines suppressed metastatic potential and prolonged the survival of tumor-bearing mice.

  2. Together these results suggest that PHIP1 regulates postnatal growth in an IGF-1 (zeige IGF1 Proteine)/AKT (zeige AKT1 Proteine) pathway-independent manner.

  3. Identification of a WD40 (zeige DCAF12L2 Proteine) repeat-containing isoform of Phip as a novel regulator of beta-cell growth and survival.

Pleckstrin Homology Domain Interacting Protein (PHIP) Protein Überblick

Protein Überblick

PHIP binds the pleckstrin homology (PH) domain of insulin receptor substrate-1 (IRS1\; MIM 147545), modulates insulin signaling, and plays a role in pancreatic beta cell growth and survival (Farhang-Fallah et al., 2000

Alternative names and synonyms associated with Pleckstrin Homology Domain Interacting Protein (PHIP)

  • pleckstrin homology domain interacting protein (PHIP)
  • pleckstrin homology domain interacting protein (phip)
  • pleckstrin homology domain interacting protein (Phip)
  • 2810004D21Rik Protein
  • 4632404O06Rik Protein
  • BRWD2 Protein
  • DCAF14 Protein
  • Ndrp Protein
  • PHIP Protein
  • Wdr11 Protein

Bezeichner auf Proteinebene für PHIP

pleckstrin homology domain interacting protein , WD repeat domain 11 , bromodomain and WD repeat domain containing 2 , WD repeat-containing protein 11-like , DDB1 and CUL4 associated factor 14 , IRS-1 PH domain-binding protein , PH-interacting protein , WD repeat-containing protein 11 , neuronal differentiation related protein , neuronal differentiation-related protein

GENE ID SPEZIES
472253 Pan troglodytes
474976 Canis lupus familiaris
523186 Bos taurus
100158567 Xenopus (Silurana) tropicalis
100359323 Oryctolagus cuniculus
100389472 Callithrix jacchus
100482484 Ailuropoda melanoleuca
100597802 Nomascus leucogenys
55023 Homo sapiens
83946 Mus musculus
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