EEF1E1 Proteine (EEF1E1)

Bezeichnung:
Eukaryotic Translation Elongation Factor 1 epsilon 1 Proteine (EEF1E1)
Auf www.antikoerper-online.de finden Sie aktuell 11 Eukaryotic Translation Elongation Factor 1 epsilon 1 (EEF1E1) Proteine von 7 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen EEF1E1 Antikörper (47) und EEF1E1 Kits (2) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 65 EEF1E1 Produkte verfügbar.
Synonyme:
1110003A02Rik, AIMP3, P18
alle Proteine anzeigen Gen GeneID UniProt
EEF1E1 9521 O43324
EEF1E1 66143 Q9D1M4
Ratte EEF1E1 EEF1E1 291057  

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Am meisten referenzierte EEF1E1 Proteine

  1. Human EEF1E1 Protein expressed in Escherichia coli (E. coli) - ABIN667425 : Norcum: Structural analysis of the high molecular mass aminoacyl-tRNA synthetase complex. Effects of neutral salts and detergents. in The Journal of biological chemistry 1991 (PubMed)
    Zeige alle 2 Referenzen für 667425

  2. Human EEF1E1 Protein expressed in Escherichia coli (E. coli) - ABIN2006038 : Quevillon, Robinson, Berthonneau, Siatecka, Mirande: Macromolecular assemblage of aminoacyl-tRNA synthetases: identification of protein-protein interactions and characterization of a core protein. in Journal of molecular biology 1999 (PubMed)

Weitere Proteine zu EEF1E1 Interaktionspartnern

Human Eukaryotic Translation Elongation Factor 1 epsilon 1 (EEF1E1) Interaktionspartner

  1. analysis of the heterotetrameric complex structure of the glutathione transferase (GST (zeige SLCO6A1 Proteine)) domains shared among the four MSC (zeige MSC Proteine) components, methionyl-tRNA synthetase (MRS), glutaminyl-prolyl-tRNA synthetase (EPRS (zeige EPRS Proteine)), AIMP2 (zeige AIMP2 Proteine) and AIMP3

  2. AIMP3 was shown to be involved in the cellular aging of human mesenchymal stem cells.

  3. Identification of EEf1E1 and OBFC2B as novel BRCA1-partner genes in the DNA double-strand break repair pathway.

  4. AIMP3 stabilizes and protects methionyl-tRNA synthetase and eIF2gamma (zeige EIF2S3 Proteine) through the binding interactions.

  5. AIMP3 is a critical mediator of Met-tRNA(i)(Met) transfer from methionyl-tRNA synthetase to eIF2 (zeige EIF2S1 Proteine) complex for the accurate and efficient translation initiation

  6. Data show that aminoacyl-tRNA synthetase-interacting multifunctional protein-3 (zeige HSPB3 Proteine) (AIMP3)/p18 is released from aminoacyl-tRNA synthetase-interacting multifunctional protein-3 (zeige HSPB3 Proteine) (AIMP3) by UV irradiation-induced stress.

  7. Decreased expression of AIMP3 in gastric and colorectal cancer tissues suggests that down-regulation of this protein may be related to inactivation of the tumor suppressor functions of AIMP proteins and might play a role in the development of GC and CRC (zeige CALR Proteine).

  8. p18 (zeige CDKN2C Proteine) is a haploinsufficient tumor suppressor and a key factor for ATM (zeige ATM Proteine)/ATR (zeige ANTXR1 Proteine)-mediated p53 (zeige TP53 Proteine) activation.

  9. analysis of the three-dimensional structure and residues of the novel tumor suppressor AIMP3/p18 required for the interaction with

  10. No EEF1E1 mutations were detected in human cancer specimens.

Mouse (Murine) Eukaryotic Translation Elongation Factor 1 epsilon 1 (EEF1E1) Interaktionspartner

  1. AIMP3 is a specific regulator of mature lamin A (zeige LMNA Proteine) and imply that enhanced expression of AIMP3 might be a factor driving cellular and/or organismal aging [AIMP3]

EEF1E1 Protein Überblick

Protein Überblick

This gene encodes a multifunctional protein that localizes to both the cytoplasm and nucleus. In the cytoplasm, the encoded protein is an auxiliary component of the macromolecular aminoacyl-tRNA synthase complex. However, its mouse homolog has been shown to translocate to the nucleus in response to DNA damage, and it plays a positive role in ATM/ATR-mediated p53 activation. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the neighboring downstream MUTED (muted homolog) gene. An EEF1E1-related pseudogene has been identified on chromosome 2.

Alternative names and synonyms associated with EEF1E1

  • eukaryotic translation elongation factor 1 epsilon 1 (EEF1E1)
  • eukaryotic translation elongation factor 1 epsilon 1 (eef1e1)
  • eukaryotic translation elongation factor 1 epsilon 1 (Eef1e1)
  • 1110003A02Rik Protein
  • AIMP3 Protein
  • P18 Protein

Bezeichner auf Proteinebene für EEF1E1

eukaryotic translation elongation factor 1 epsilon 1 , eukaryotic translation elongation factor 1 epsilon-1 , ARS-interacting multifunctional protein 3 , aminoacyl tRNA synthetase complex-interacting multifunctional protein 3 , multisynthase complex auxiliary component p18 , p18 component of aminoacyl-tRNA synthetase complex , elongation factor p18 , multisynthetase complex auxiliary component p18 , Elongation factor p18 , Multisynthase complex auxiliary component p18

GENE ID SPEZIES
420865 Gallus gallus
462423 Pan troglodytes
478717 Canis lupus familiaris
495305 Xenopus laevis
617105 Bos taurus
695426 Macaca mulatta
100038230 Xenopus (Silurana) tropicalis
100135689 Ovis aries
9521 Homo sapiens
66143 Mus musculus
291057 Rattus norvegicus
100689310 Cricetulus griseus
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