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The C-terminal domain of BAP31 is exposed on the cell surface of mouse embryonic stem cells.
BAP31/CDIP1-mediated regulation of mitochondrial apoptosis pathway represents a mechanism for establishing an ER-mitochondrial crosstalk for ER-stress-mediated apoptosis.
Data suggest that endoplasmic reticulum-localized Bcl2 (zeige BCL2 ELISA Kits) protects against a Bax (zeige BAX ELISA Kits)/Bak (zeige BAK1 ELISA Kits)-independent cell death pathway initiated by the p20 (zeige HSPB6 ELISA Kits) fragment of Bap31.
A high-molecular-weight complex of membrane proteins BAP29/BAP31 is involved in the retention of membrane-bound IgD in the endoplasmic reticulum.
results are consistent with the view that class I molecules are largely recruited to ER exit sites by Bap29/31, and that Bap29/31 is a cargo receptor for MHC class I molecules
p20 (zeige HSPB6 ELISA Kits) BAP31 can operate upstream of BCL-2 (zeige BCL2 ELISA Kits) in living cells to influence cell surface properties due to its effects on protein egress from the endoplasmic reticulum
These results suggest that a compositional change of AMPA (zeige GRIA3 ELISA Kits) receptor (increase of GluR1 (zeige GRIA1 ELISA Kits)) and upregulation of the Bap31 gene may be implicated in fatigue in mice.
interaction of P450 (zeige POR ELISA Kits) 2C2 with BAP31 is important for its ER retention and expression level and that BAP31 may be involved in the regulation of apoptosis induced by the ER overload response to increased expression of P450 (zeige POR ELISA Kits).
This patient's clinical features, muscle histopathology, brain MRI (zeige C7ORF49 ELISA Kits) features, and family history were suggestive of mitochondrial encephalopathy. Whole exome sequencing research study confirmed the diagnosis of BCAP31-associated encephalopathy, DDCH syndrome.
Data characterized the biochemical properties of plant orthologs of human B-cell receptor-associated protein BAP31 (HsBAP31) termed 'plant BAP (zeige PHB2 ELISA Kits)-like proteins' (PBL proteins).
Data show that tumor necrosis factor (zeige TNF ELISA Kits)-related apoptosis-inducing ligand (TRAIL)-induced endoplasmic reticulum (ER) stress was triggered by caspase-8 (zeige CASP8 ELISA Kits)-mediated cleavage of B cell receptor-associated protein 31 (BAP31).
The C-terminal domain of BAP31 is exposed on the cell surface of human embryonic stem cells.
both BCAP31 and ABCD1 (zeige ABCD1 ELISA Kits) were associated with hepatic cholestasis and death before 1 year. Remarkably, a patient with an isolated deletion at the 3'-end of SLC6A8 (zeige SLC6A8 ELISA Kits) had a similar severe phenotype as seen in BCAP31 deficiency
Transfected human respiratory syncytial virus SH protein co-localizes with transfected BAP31 in cells, and pulls down endogenous BAP31.
These findings provide, for the first time, mechanistic insights into how BAP31 regulates human embryonic stem cell stemness and survival via control of EpCAM (zeige EPCAM ELISA Kits) expression.
Hypomethylation in BCAP31 is associated with breast cancer.
the lack of BAP31 disturbs endoplasmic reticulum (ER) metabolism and impacts the Golgi apparatus, highlighting an important role for BAP31 in ER-to-Golgi crosstalk.
BAP31 and BiP (zeige GDF10 ELISA Kits) are essential for dislocation of SV40 from the endoplasmic reticulum to the cytosol.
The data provide the first functional assessment of the role of caldesmon (zeige CALD1 ELISA Kits) in cardiac development in vivo, and indicate that caldesmon (zeige CALD1 ELISA Kits) is essential for proper cardiac organogenesis and function.
This gene encodes a member of the B-cell receptor associated protein 31 superfamily. The encoded protein is a multi-pass transmembrane protein of the endoplasmic reticulum that is involved in the anterograde transport of membrane proteins from the endoplasmic reticulum to the Golgi and in caspase 8-mediated apoptosis. Microdeletions in this gene are associated with contiguous ABCD1/DXS1375E deletion syndrome (CADDS), a neonatal disorder. Alternative splicing of this gene results in multiple transcript variants. Two related pseudogenes have been identified on chromosome 16.
, lipopeptide mating pheromone precursor bap3-1
, B-cell receptor-associated protein 31
, BCR-associated protein 31
, accessory protein BAP31
, 6C6-AG tumor-associated antigen
, BCR-associated protein Bap31
, p28 Bap31