MAPKAP1 (MAPKAP1) ELISA Kits

Bezeichnung:
Mitogen-Activated Protein Kinase Associated Protein 1 ELISA Kits (MAPKAP1)
Auf www.antikoerper-online.de finden Sie aktuell 5 Mitogen-Activated Protein Kinase Associated Protein 1 (MAPKAP1) ELISA Kits von 1 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen MAPKAP1 Antikörper (85) und MAPKAP1 Proteine (4) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 103 MAPKAP1 Produkte verfügbar.
Synonyme:
AI591529, CG10105, D230039K05Rik, Dmel\\CG10105, dSin1, im:7143088, JC310, MAPKAP1, MGC53034, MIP1, si:ch73-242f23.1, Sin1, SIN1b, SIN1g

Weitere ELISA Kits für MAPKAP1 Interaktionspartner

Fruit Fly (Drosophila melanogaster) Mitogen-Activated Protein Kinase Associated Protein 1 (MAPKAP1) Interaktionspartner

  1. Sin1, Rictor, Trc and target of rapamycin (TOR), components of the TOR complex 2 (TORC2), are required for dendritic tiling of class IV da neurons

Human Mitogen-Activated Protein Kinase Associated Protein 1 (MAPKAP1) Interaktionspartner

  1. SIN1 plays an important role in non-small cell lung cancer; SIN1 is a potential biomarker and a promising target in the treatment of NSCLC

  2. This study provides evidence that Sin1, a known element of the mammalian target of rapamycin (zeige FRAP1 ELISA Kits) complex 2 (mTORC2 (zeige CRTC2 ELISA Kits)), is required for Interferon-gamma (zeige IFNG ELISA Kits)-induced phosphorylation and activation of AKT (zeige AKT1 ELISA Kits) and that such activation mediates downstream regulation of mTORC1 and its effectors.

  3. Intracellular localization of mTORC2 (zeige CRTC2 ELISA Kits) component, mSin1, contributes to regulation of Akt (zeige AKT1 ELISA Kits) phosphorylation.

  4. Akt (zeige AKT1 ELISA Kits) phosphorylates SIN1 at T86, enhancing mTORC2 (zeige CRTC2 ELISA Kits) kinase activity, which leads to phosphorylation of Akt (zeige AKT1 ELISA Kits) S473 by mTORC2 (zeige CRTC2 ELISA Kits), thereby catalyzing full activation of Akt (zeige AKT1 ELISA Kits).

  5. MAPKAP1 may represent a novel anti-infection and anti-fibrogenesis genomic locus in chronic schistosomiasis japonica.

  6. mitogen-activated protein kinase associated protein 1 rs10118570 may be an important protective factor for developing better management strategies in lung squamous cell carcinoma.

  7. DNA-PKcs (zeige PRKDC ELISA Kits)-mTORC2 (zeige CRTC2 ELISA Kits)(SIN1) association is required for UVB-induced Akt (zeige AKT1 ELISA Kits) Ser (zeige SIGLEC1 ELISA Kits)-473 phosphorylation and cell survival.

  8. Estradiol and mTORC2 (zeige CRTC2 ELISA Kits) cooperate to enhance prostaglandin biosynthesis and tumorigenesis in TSC2 (zeige TSC2 ELISA Kits)-deficient lymphangioleiomyomatosis cells.

  9. results reveal a Sin1-phosphorylation-dependent mTORC2 (zeige CRTC2 ELISA Kits) regulation, providing a potential molecular mechanism by which mutations in the mTORC1-S6K (zeige RPS6KB1 ELISA Kits)-Sin1 signalling axis might cause aberrant hyper-activation of the mTORC2 (zeige CRTC2 ELISA Kits)-Akt (zeige AKT1 ELISA Kits) pathway

  10. NBS1 (zeige NBN ELISA Kits) interacts with the mTOR (zeige FRAP1 ELISA Kits)/Rictor (zeige RICTOR ELISA Kits)/SIN1 complex through the a.a. 221-402 domain and contributes to the activation of Akt (zeige AKT1 ELISA Kits) activity.

Mouse (Murine) Mitogen-Activated Protein Kinase Associated Protein 1 (MAPKAP1) Interaktionspartner

  1. This study provides evidence that Sin1, a known element of the mammalian target of rapamycin (zeige FRAP1 ELISA Kits) complex 2 (mTORC2 (zeige CRTC2 ELISA Kits)), is required for Interferon-gamma (zeige IFNG ELISA Kits)-induced phosphorylation and activation of AKT (zeige AKT1 ELISA Kits) and that such activation mediates downstream regulation of mTORC1 and its effectors.

  2. analysis of mTORC2 (zeige CRTC2 ELISA Kits) components mTOR (zeige FRAP1 ELISA Kits), Rictor (zeige RICTOR ELISA Kits) and mSin1 reveals diurnal variation in mouse perivascular adipose tissue

  3. data suggest that DNA-PKcs (zeige PRKDC ELISA Kits)-SIN1 complexation-mediated Akt (zeige AKT1 ELISA Kits) activation (Ser (zeige SIGLEC1 ELISA Kits)-473 phosphorylation) is required for mouse osteoblast differentiation

  4. these findings provide evidence for critical functions for Rictor (zeige RICTOR ELISA Kits)/Sin1 complexes in type I IFN signaling and the generation of type I IFN antineoplastic responses.

  5. The phosphorylation of SIN1 by Akt (zeige AKT1 ELISA Kits) was found to regulate mTORC2 (zeige CRTC2 ELISA Kits) activity in response to growth factors, revealing topological insights into the Akt (zeige AKT1 ELISA Kits)/mTOR (zeige FRAP1 ELISA Kits) signaling network.

  6. Sin1 and mTORC2 (zeige CRTC2 ELISA Kits) are dispensable for the development and activation of T cells but play a role in nTreg-cell differentiation.

  7. mSIN1 protein mediates SGK1 (zeige SGK1 ELISA Kits) protein interaction with mTORC2 (zeige CRTC2 ELISA Kits) protein complex and is required for selective activation of the epithelial sodium channel

  8. MAP kinase (zeige MAPK1 ELISA Kits)-interacting kinase 1 and 2 activity enhances formation of the EIF-4F complex in pachytene spermatocytes but not in round spermatids.

  9. Sin1-mTORC2 (zeige CRTC2 ELISA Kits) suppresses rag1,2 and il7r (zeige IL7R ELISA Kits) gene expression through Akt2 (zeige AKT2 ELISA Kits) in B cells.

  10. Results reveal that the SIN1-rictor (zeige RICTOR ELISA Kits)-mTOR (zeige FRAP1 ELISA Kits) function in Akt (zeige AKT1 ELISA Kits)-Ser473 phosphorylation is required for TORC2 (zeige CRTC2 ELISA Kits) function in cell survival but is dispensable for TORC1 (zeige CRTC1 ELISA Kits) function.

MAPKAP1 Antigen-Profil

Beschreibung des Gens

This gene encodes a protein that is highly similar to the yeast SIN1 protein, a stress-activated protein kinase. Alternatively spliced transcript variants encoding distinct isoforms have been described. Alternate polyadenylation sites as well as alternate 3' UTRs have been identified for transcripts of this gene.

Alternative names and synonyms associated with MAPKAP1

  • SAPK-interacting protein 1 (Sin1) Elisa Kit
  • mitogen-activated protein kinase associated protein 1 (MAPKAP1) Elisa Kit
  • mitogen-activated protein kinase associated protein 1 (mapkap1) Elisa Kit
  • mitogen-activated protein kinase associated protein 1 (Mapkap1) Elisa Kit
  • AI591529 Elisa Kit
  • CG10105 Elisa Kit
  • D230039K05Rik Elisa Kit
  • Dmel\\CG10105 Elisa Kit
  • dSin1 Elisa Kit
  • im:7143088 Elisa Kit
  • JC310 Elisa Kit
  • MAPKAP1 Elisa Kit
  • MGC53034 Elisa Kit
  • MIP1 Elisa Kit
  • si:ch73-242f23.1 Elisa Kit
  • Sin1 Elisa Kit
  • SIN1b Elisa Kit
  • SIN1g Elisa Kit

Bezeichner auf Proteinebene für MAPKAP1

CG10105-PA , Sin1-PA , Stress-activated protein kinase [SAPK]-interacting protein , stress-activated map kinase-interacting protein 1 , mitogen-activated protein kinase associated protein 1 , Target of rapamycin complex 2 subunit MAPKAP1 , target of rapamycin complex 2 subunit MAPKAP1-like , MEKK2-interacting protein 1 , SAPK-interacting protein 1 , TORC2 subunit MAPKAP1 , mSIN1 , mitogen-activated protein kinase 2-associated protein 1 , ras inhibitor MGC2745 , stress-activated map kinase interacting protein 1 , stress-activated protein kinase-interacting 1 , target of rapamycin complex 2 subunit MAPKAP1 , mitogen activated protein kinase associated protein 1 , SAPK interacting protein

GENE ID SPEZIES
36604 Drosophila melanogaster
464736 Pan troglodytes
480724 Canis lupus familiaris
492604 Danio rerio
100101680 Xenopus (Silurana) tropicalis
100390680 Callithrix jacchus
100481486 Ailuropoda melanoleuca
100601949 Nomascus leucogenys
79109 Homo sapiens
227743 Mus musculus
296648 Rattus norvegicus
533861 Bos taurus
395627 Gallus gallus
380158 Xenopus laevis
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