anti-MAPKAP1 (MAPKAP1) Antikörper

Bezeichnung:
anti-Mitogen-Activated Protein Kinase Associated Protein 1 Antikörper (MAPKAP1)
Auf www.antikoerper-online.de finden Sie aktuell 85 Mitogen-Activated Protein Kinase Associated Protein 1 (MAPKAP1) Antikörper von 21 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen MAPKAP1 Kits (5) und MAPKAP1 Proteine (4) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 103 MAPKAP1 Produkte verfügbar.
Synonyme:
AI591529, CG10105, D230039K05Rik, Dmel\\CG10105, dSin1, im:7143088, JC310, MAPKAP1, MGC53034, MIP1, si:ch73-242f23.1, Sin1, SIN1b, SIN1g

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anti-Human MAPKAP1 Antikörper:

anti-Mouse (Murine) MAPKAP1 Antikörper:

anti-Rat (Rattus) MAPKAP1 Antikörper:

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Am meisten referenzierte anti-MAPKAP1 Antikörper

  1. Human Polyclonal MAPKAP1 Primary Antibody für ICC, IF - ABIN258134 : Huang, Wu, Wu, Manning: Signaling events downstream of mammalian target of rapamycin complex 2 are attenuated in cells and tumors deficient for the tuberous sclerosis complex tumor suppressors. in Cancer research 2009 (PubMed)
    Zeige alle 4 Referenzen für 258134

  2. Human Polyclonal MAPKAP1 Primary Antibody für IHC, ELISA - ABIN1002804 : Cheng, Zhang, Kim, Zhao, Zhao, Su: Mip1, an MEKK2-interacting protein, controls MEKK2 dimerization and activation. in Molecular and cellular biology 2005 (PubMed)
    Zeige alle 4 Referenzen für 1002804

  3. Human Polyclonal MAPKAP1 Primary Antibody für IHC, ELISA - ABIN1002803 : Schroder, Cloonan, Bushell, Sculley: Alternative polyadenylation and splicing of mRNAs transcribed from the human Sin1 gene. in Gene 2004 (PubMed)
    Zeige alle 4 Referenzen für 1002803

  4. Human Polyclonal MAPKAP1 Primary Antibody für IHC (p), WB - ABIN2475490 : Xia, Gu, Xu, Wang, Yang, Xu, Qian, Chen: Construction of a genomic DNA library of the Toxoplasma gondii ZS2 strain, screening of specific clones, and DNA diagnosis of toxoplasmosis. in The American journal of tropical medicine and hygiene 1992 (PubMed)
    Zeige alle 4 Referenzen für 2475490

  5. Human Polyclonal MAPKAP1 Primary Antibody für ICFC - ABIN2665262 : Schroder, Bushell, Sculley: The human stress-activated protein kinase-interacting 1 gene encodes JNK-binding proteins. in Cellular signalling 2005 (PubMed)
    Zeige alle 3 Referenzen für 2665262

Weitere Antikörper gegen MAPKAP1 Interaktionspartner

Fruit Fly (Drosophila melanogaster) Mitogen-Activated Protein Kinase Associated Protein 1 (MAPKAP1) Interaktionspartner

  1. Sin1, Rictor, Trc and target of rapamycin (TOR), components of the TOR complex 2 (TORC2), are required for dendritic tiling of class IV da neurons

Human Mitogen-Activated Protein Kinase Associated Protein 1 (MAPKAP1) Interaktionspartner

  1. SIN1 plays an important role in non-small cell lung cancer; SIN1 is a potential biomarker and a promising target in the treatment of NSCLC

  2. This study provides evidence that Sin1, a known element of the mammalian target of rapamycin (zeige FRAP1 Antikörper) complex 2 (mTORC2 (zeige CRTC2 Antikörper)), is required for Interferon-gamma (zeige IFNG Antikörper)-induced phosphorylation and activation of AKT (zeige AKT1 Antikörper) and that such activation mediates downstream regulation of mTORC1 and its effectors.

  3. Intracellular localization of mTORC2 (zeige CRTC2 Antikörper) component, mSin1, contributes to regulation of Akt (zeige AKT1 Antikörper) phosphorylation.

  4. Akt (zeige AKT1 Antikörper) phosphorylates SIN1 at T86, enhancing mTORC2 (zeige CRTC2 Antikörper) kinase activity, which leads to phosphorylation of Akt (zeige AKT1 Antikörper) S473 by mTORC2 (zeige CRTC2 Antikörper), thereby catalyzing full activation of Akt (zeige AKT1 Antikörper).

  5. MAPKAP1 may represent a novel anti-infection and anti-fibrogenesis genomic locus in chronic schistosomiasis japonica.

  6. mitogen-activated protein kinase associated protein 1 rs10118570 may be an important protective factor for developing better management strategies in lung squamous cell carcinoma.

  7. DNA-PKcs (zeige PRKDC Antikörper)-mTORC2 (zeige CRTC2 Antikörper)(SIN1) association is required for UVB-induced Akt (zeige AKT1 Antikörper) Ser (zeige SIGLEC1 Antikörper)-473 phosphorylation and cell survival.

  8. Estradiol and mTORC2 (zeige CRTC2 Antikörper) cooperate to enhance prostaglandin biosynthesis and tumorigenesis in TSC2 (zeige TSC2 Antikörper)-deficient lymphangioleiomyomatosis cells.

  9. results reveal a Sin1-phosphorylation-dependent mTORC2 (zeige CRTC2 Antikörper) regulation, providing a potential molecular mechanism by which mutations in the mTORC1-S6K (zeige RPS6KB1 Antikörper)-Sin1 signalling axis might cause aberrant hyper-activation of the mTORC2 (zeige CRTC2 Antikörper)-Akt (zeige AKT1 Antikörper) pathway

  10. NBS1 (zeige NBN Antikörper) interacts with the mTOR (zeige FRAP1 Antikörper)/Rictor (zeige RICTOR Antikörper)/SIN1 complex through the a.a. 221-402 domain and contributes to the activation of Akt (zeige AKT1 Antikörper) activity.

Mouse (Murine) Mitogen-Activated Protein Kinase Associated Protein 1 (MAPKAP1) Interaktionspartner

  1. This study provides evidence that Sin1, a known element of the mammalian target of rapamycin (zeige FRAP1 Antikörper) complex 2 (mTORC2 (zeige CRTC2 Antikörper)), is required for Interferon-gamma (zeige IFNG Antikörper)-induced phosphorylation and activation of AKT (zeige AKT1 Antikörper) and that such activation mediates downstream regulation of mTORC1 and its effectors.

  2. analysis of mTORC2 (zeige CRTC2 Antikörper) components mTOR (zeige FRAP1 Antikörper), Rictor (zeige RICTOR Antikörper) and mSin1 reveals diurnal variation in mouse perivascular adipose tissue

  3. data suggest that DNA-PKcs (zeige PRKDC Antikörper)-SIN1 complexation-mediated Akt (zeige AKT1 Antikörper) activation (Ser (zeige SIGLEC1 Antikörper)-473 phosphorylation) is required for mouse osteoblast differentiation

  4. these findings provide evidence for critical functions for Rictor (zeige RICTOR Antikörper)/Sin1 complexes in type I IFN signaling and the generation of type I IFN antineoplastic responses.

  5. The phosphorylation of SIN1 by Akt (zeige AKT1 Antikörper) was found to regulate mTORC2 (zeige CRTC2 Antikörper) activity in response to growth factors, revealing topological insights into the Akt (zeige AKT1 Antikörper)/mTOR (zeige FRAP1 Antikörper) signaling network.

  6. Sin1 and mTORC2 (zeige CRTC2 Antikörper) are dispensable for the development and activation of T cells but play a role in nTreg-cell differentiation.

  7. mSIN1 protein mediates SGK1 (zeige SGK1 Antikörper) protein interaction with mTORC2 (zeige CRTC2 Antikörper) protein complex and is required for selective activation of the epithelial sodium channel

  8. MAP kinase (zeige MAPK1 Antikörper)-interacting kinase 1 and 2 activity enhances formation of the EIF-4F complex in pachytene spermatocytes but not in round spermatids.

  9. Sin1-mTORC2 (zeige CRTC2 Antikörper) suppresses rag1,2 and il7r (zeige IL7R Antikörper) gene expression through Akt2 (zeige AKT2 Antikörper) in B cells.

  10. Results reveal that the SIN1-rictor (zeige RICTOR Antikörper)-mTOR (zeige FRAP1 Antikörper) function in Akt (zeige AKT1 Antikörper)-Ser473 phosphorylation is required for TORC2 (zeige CRTC2 Antikörper) function in cell survival but is dispensable for TORC1 (zeige CRTC1 Antikörper) function.

MAPKAP1 Antigen-Profil

Beschreibung des Gens

This gene encodes a protein that is highly similar to the yeast SIN1 protein, a stress-activated protein kinase. Alternatively spliced transcript variants encoding distinct isoforms have been described. Alternate polyadenylation sites as well as alternate 3' UTRs have been identified for transcripts of this gene.

Alternative names and synonyms associated with MAPKAP1

  • SAPK-interacting protein 1 (Sin1) Antikörper
  • mitogen-activated protein kinase associated protein 1 (MAPKAP1) Antikörper
  • mitogen-activated protein kinase associated protein 1 (mapkap1) Antikörper
  • mitogen-activated protein kinase associated protein 1 (Mapkap1) Antikörper
  • AI591529 Antikörper
  • CG10105 Antikörper
  • D230039K05Rik Antikörper
  • Dmel\\CG10105 Antikörper
  • dSin1 Antikörper
  • im:7143088 Antikörper
  • JC310 Antikörper
  • MAPKAP1 Antikörper
  • MGC53034 Antikörper
  • MIP1 Antikörper
  • si:ch73-242f23.1 Antikörper
  • Sin1 Antikörper
  • SIN1b Antikörper
  • SIN1g Antikörper

Bezeichner auf Proteinebene für MAPKAP1

CG10105-PA , Sin1-PA , Stress-activated protein kinase [SAPK]-interacting protein , stress-activated map kinase-interacting protein 1 , mitogen-activated protein kinase associated protein 1 , Target of rapamycin complex 2 subunit MAPKAP1 , target of rapamycin complex 2 subunit MAPKAP1-like , MEKK2-interacting protein 1 , SAPK-interacting protein 1 , TORC2 subunit MAPKAP1 , mSIN1 , mitogen-activated protein kinase 2-associated protein 1 , ras inhibitor MGC2745 , stress-activated map kinase interacting protein 1 , stress-activated protein kinase-interacting 1 , target of rapamycin complex 2 subunit MAPKAP1 , mitogen activated protein kinase associated protein 1 , SAPK interacting protein

GENE ID SPEZIES
36604 Drosophila melanogaster
464736 Pan troglodytes
480724 Canis lupus familiaris
492604 Danio rerio
100101680 Xenopus (Silurana) tropicalis
100390680 Callithrix jacchus
100481486 Ailuropoda melanoleuca
100601949 Nomascus leucogenys
79109 Homo sapiens
227743 Mus musculus
296648 Rattus norvegicus
533861 Bos taurus
395627 Gallus gallus
380158 Xenopus laevis
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