This is a synthetic peptide designed for use in combination with anti-HOMER3 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
Each Investigator should determine their own optimal working dilution for specific applications.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Lyophilized
Rekonstitution
Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
Konzentration
1 mg/mL
Buffer
Final peptide concentration is 1 mg/mL in PBS.
Handhabung
Avoid repeated freeze-thaw cycles.
Lagerung
-20 °C
Informationen zur Lagerung
For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
Target
HOMER3
(Homer Homolog 3 (Drosophila) (HOMER3))
Synonyme
zgc:55557 Peptide, HOMER-3 Peptide, VESL3 Peptide, AW146114 Peptide, Vesl-3 Peptide, homer scaffolding protein 3b Peptide, homer scaffolding protein 3 Peptide, homer3b Peptide, HOMER3 Peptide, Homer3 Peptide
Hintergrund
This gene encodes a member of the HOMER family of postsynaptic density scaffolding proteins that share a similar domain structure consisting of an N-terminal Enabled/vasodilator-stimulated phosphoprotein homology 1 domain which mediates protein-protein interactions, and a carboxy-terminal coiled-coil domain and two leucine zipper motifs that are involved in self-oligomerization. The encoded protein binds numerous other proteins including group I metabotropic glutamate receptors, inositol 1,4,5-trisphosphate receptors and amyloid precursor proteins and has been implicated in diverse biological functions such as neuronal signaling, T-cell activation and trafficking of amyloid beta peptides. Alternative splicing results in multiple transcript variants.
Alias Symbols: HOMER-3, VESL3
Protein Interaction Partner: GRM5,CEBPB,DYNLL2,FAT1,GRM5,HOMER1,ITPR1,PAX6,RYR1,DYNLL2,FRYL,RYR1,TRPC1,TRPC4,TRPC5