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Homer Homolog 3 (Drosophila) (HOMER3) (C-Term) Peptid

HOMER3 Reaktivität: Human Wirt: Synthetic BP, WB
Produktnummer ABIN978127
  • Target Alle HOMER3 Produkte
    HOMER3 (Homer Homolog 3 (Drosophila) (HOMER3))
    Protein Region
    C-Term
    Spezies
    Human
    Quelle
    • 2
    Synthetic
    Applikation
    Blocking Peptide (BP), Western Blotting (WB)
    Sequenz
    HQLRAMERSL EEARAERERA RAEVGRAAQL LDVSLFELSE LREGLARLAE
    Produktmerkmale
    This is a synthetic peptide designed for use in combination with anti-HOMER3 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Aufreinigung
    Purified
  • Applikationshinweise
    Each Investigator should determine their own optimal working dilution for specific applications.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Konzentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Handhabung
    Avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    HOMER3 (Homer Homolog 3 (Drosophila) (HOMER3))
    Synonyme
    zgc:55557 Peptide, HOMER-3 Peptide, VESL3 Peptide, AW146114 Peptide, Vesl-3 Peptide, homer scaffolding protein 3b Peptide, homer scaffolding protein 3 Peptide, homer3b Peptide, HOMER3 Peptide, Homer3 Peptide
    Hintergrund
    This gene encodes a member of the HOMER family of postsynaptic density scaffolding proteins that share a similar domain structure consisting of an N-terminal Enabled/vasodilator-stimulated phosphoprotein homology 1 domain which mediates protein-protein interactions, and a carboxy-terminal coiled-coil domain and two leucine zipper motifs that are involved in self-oligomerization. The encoded protein binds numerous other proteins including group I metabotropic glutamate receptors, inositol 1,4,5-trisphosphate receptors and amyloid precursor proteins and has been implicated in diverse biological functions such as neuronal signaling, T-cell activation and trafficking of amyloid beta peptides. Alternative splicing results in multiple transcript variants.

    Alias Symbols: HOMER-3, VESL3

    Protein Interaction Partner: GRM5,CEBPB,DYNLL2,FAT1,GRM5,HOMER1,ITPR1,PAX6,RYR1,DYNLL2,FRYL,RYR1,TRPC1,TRPC4,TRPC5

    Protein Size: 358
    Molekulargewicht
    39 kDa
    Gen-ID
    9454
    NCBI Accession
    NM_001145721, NP_001139193
    UniProt
    Q9NSC5
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