F-Box Protein 33 (FBXO33) (Middle Region) Peptid
FBXO33
Reaktivität: Human
Wirt: Synthetic
BP, WB
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- Target Alle FBXO33 Produkte
- FBXO33 (F-Box Protein 33 (FBXO33))
- Protein Region
- Middle Region
- Spezies
- Human
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Quelle
- Synthetic
- Applikation
- Blocking Peptide (BP), Western Blotting (WB)
- Produktmerkmale
- This is a synthetic peptide designed for use in combination with anti-FBXO33 antibody (Catalog #: ARP55943_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Aufreinigung
- Purified
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- Applikationshinweise
- Each Investigator should determine their own optimal working dilution for specific applications.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Rekonstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Konzentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- FBXO33 (F-Box Protein 33 (FBXO33))
- Synonyme
- FBXO33 Peptide, BMND12 Peptide, Fbx33 Peptide, c14_5247 Peptide, 5730501N20Rik Peptide, AI642135 Peptide, F-box protein 33 Peptide, F-box protein 33 S homeolog Peptide, FBXO33 Peptide, fbxo33 Peptide, fbxo33.S Peptide, Fbxo33 Peptide
- Hintergrund
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FBXO33 is the substrate recognition component of a (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. FBXO33 probably recognizes and binds to phosphorylated target proteins. Recognizes YBX1.Members of the F-box protein family, such as FBXO33, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1, MIM 603134), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (Jin et al., 2004 [PubMed 15520277]).[supplied by OMIM].
Alias Symbols: Fbx33, c14_5247, BMND12
Protein Interaction Partner: YBX1
Protein Size: 555 - Molekulargewicht
- 62 kDa
- Gen-ID
- 254170
- NCBI Accession
- NM_203301, NP_976046
- UniProt
- Q7Z6M2
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