Exosome Component 6 (EXOSC6) Peptid
EXOSC6
Reaktivität: Human
Wirt: Synthetic
BP, WB, IHC
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- Target Alle EXOSC6 Produkte
- EXOSC6 (Exosome Component 6 (EXOSC6))
- Spezies
- Human
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Quelle
- Synthetic
- Applikation
- Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
- Produktmerkmale
- This is a synthetic peptide designed for use in combination with anti-EXOSC6 antibody (Catalog #: ARP41087_T100). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Aufreinigung
- Purified
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- Applikationshinweise
- Each Investigator should determine their own optimal working dilution for specific applications.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Rekonstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Konzentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- EXOSC6 (Exosome Component 6 (EXOSC6))
- Synonyme
- exosc6 Peptide, RAR-gamma Peptide, id:ibd1130 Peptide, wu:fe17d05 Peptide, zgc:110071 Peptide, EAP4 Peptide, MTR3 Peptide, Mtr3p Peptide, hMtr3p Peptide, p11 Peptide, 2610510N21Rik Peptide, C76919 Peptide, Mtr3 Peptide, exosome component 6 Peptide, EXOSC6 Peptide, exosc6 Peptide, CpipJ_CPIJ018071 Peptide, Exosc6 Peptide
- Hintergrund
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EXOSC6 constitutes one of the subunits of the multisubunit particle called exosome, which mediates mRNA degradation. The composition of human exosome is similar to its yeast counterpart. This protein is homologous to the yeast Mtr3 protein. Its exact function is not known, however, it has been shown using a cell-free RNA decay system that the exosome is required for rapid degradation of unstable mRNAs containing AU-rich elements (AREs), but not for poly(A) shortening. The exosome does not recognize ARE-containing mRNAs on its own, but requires ARE-binding proteins that could interact with the exosome and recruit it to unstable mRNAs, thereby promoting their rapid degradation.This gene product constitutes one of the subunits of the multisubunit particle called exosome, which mediates mRNA degradation. The composition of human exosome is similar to its yeast counterpart. This protein is homologous to the yeast Mtr3 protein. Its exact function is not known, however, it has been shown using a cell-free RNA decay system that the exosome is required for rapid degradation of unstable mRNAs containing AU-rich elements (AREs), but not for poly(A) shortening. The exosome does not recognize ARE-containing mRNAs on its own, but requires ARE-binding proteins that could interact with the exosome and recruit it to unstable mRNAs, thereby promoting their rapid degradation.
Alias Symbols: p11, EAP4, MTR3, Mtr3p, hMtr3p
Protein Interaction Partner: C1QBP,CHPF,DCP1B,DIS3,DNAJC30,EIF3I,ESRRA,EXOSC10,EXOSC2,EXOSC4,EXOSC5,EXOSC6,EXOSC7,EXOSC8,EXOSC9,KIAA0182,LSM1,LSM7,MIF4GD,MOCS3,MPP6,NAA38,NDUFA13,NUDT21,PSMB1,RAB3GAP2,SKIV2L2,SRSF3,UPF2,XRN1,ZFP36,EXOSC1,EXOSC7,EXOSC8,DNAJC30,EIF3I,EXOSC1,EXOSC7,EXOSC8,LSM1,LSM7,MOCS3,NAA38,NUDT21,PSMB1,SRSF3
Protein Size: 272 - Molekulargewicht
- 30 kDa
- Gen-ID
- 118460
- NCBI Accession
- NM_058219, NP_478126
- UniProt
- Q5RKV6
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