This is a synthetic peptide designed for use in combination with anti-AMOT antibody (Catalog #: ARP34660_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
AMOT belongs to the motin family of angiostatin binding proteins characterized by conserved coiled-coil domains and C-terminal PDZ binding motifs. The protein is expressed predominantly in endothelial cells of capillaries as well as larger vessels of the placenta where it may mediate the inhibitory effect of angiostatin on tube formation and the migration of endothelial cells toward growth factors during the formation of new blood vessels. Alternative splicing results in multiple transcript variants encoding different isoforms.This gene belongs to the motin family of angiostatin binding proteins characterized by conserved coiled-coil domains and C-terminal PDZ binding motifs. The encoded protein is expressed predominantly in endothelial cells of capillaries as well as larger vessels of the placenta where it may mediate the inhibitory effect of angiostatin on tube formation and the migration of endothelial cells toward growth factors during the formation of new blood vessels. Alternative splicing results in multiple transcript variants encoding different isoforms.
Alias Symbols: KIAA1071
Protein Interaction Partner: MAGI1,PLG,AMOTL1,BAG3,DLG1,DYNLL1,DYNLL2,FOXK1,FOXK2,LIN7A,LIN7C,LONP2,MLH1,MPDZ,MPP5,MPP7,NEDD4L,NF2,NIN,SCLT1,UIMC1,USP11,USP42,YAP1