This is a synthetic peptide designed for use in combination with anti-Wnt1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
Optimal working dilution should be determined by the investigator.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Lyophilized
Rekonstitution
Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
Konzentration
1 mg/mL
Buffer
Final peptide concentration is 1 mg/mL in PBS.
Handhabung
Avoid repeat freeze-thaw cycles.
Lagerung
-20 °C
Informationen zur Lagerung
For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
Target
WNT1
(Wingless-Type MMTV Integration Site Family, Member 1 (WNT1))
Synonyme
Xint-1 Peptide, Xwnt1 Peptide, int-1 Peptide, int1 Peptide, wnt-1 Peptide, wnt1-a Peptide, Int-1 Peptide, Wnt-1 Peptide, sw Peptide, swaying Peptide, BMND16 Peptide, INT1 Peptide, OI15 Peptide, Int1 Peptide, WNT-1 Peptide, sb:eu647 Peptide, zgc:194464 Peptide, zgc:194478 Peptide, WNT1 Peptide, Wnt family member 1 Peptide, Wnt family member 1 L homeolog Peptide, wingless-type MMTV integration site family, member 1 Peptide, WNT1 Peptide, wnt1.L Peptide, Wnt1 Peptide, wnt1 Peptide
Hintergrund
Wnt1 is a ligand for members of the frizzled family of seven transmembrane receptors. In some developmental processes, it is also a ligand for the coreceptor RYK, thus triggering Wnt signaling. It is a probable developmental protein and may be a signaling molecule important in CNS development. Wnt1 is likely to signal over only few cell diameters. It ha s a proeminent role in the induction of the mesencephalon and cerebellum. It may play a crucial role in the morphogenesis of the neural tube and/or the early stages of CNS development. It has a role in osteoblast function and bone development.