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Results showed activin (zeige Actbeta Antikörper)-C and follistatin (zeige FST Antikörper) are differentially expressed during prostate development and suggested that the antagonistic property of follistatin (zeige FST Antikörper) is secondary to the action of activin (zeige Actbeta Antikörper)-C. Study provides evidence to support a role of activin (zeige Actbeta Antikörper)-C in prostate development and provides new insights in the spatiotemporal localization of activins and their antagonists during mouse prostate development.
Data reinforces the importance of activin (zeige Actbeta Antikörper)-betaC in reproductive biology and suggests that activin (zeige Actbeta Antikörper)-betaC is a tumor modulator with gonadal specificity.
Data support the conclusion that activin (zeige Actbeta Antikörper) inhibits adrenal tumor growth promoted by luteinizing hormone by inducing adrenal x-zone regression.
results indicate that the beta(C) and beta(E) subunits of activin (zeige Actbeta Antikörper) form homo- and heterodimers, and that the functions of the two subunits are quite different
Study shows an up-regulation of activin (zeige Actbeta Antikörper)-C in aggressive prostate cancer only, suggesting that activin (zeige Actbeta Antikörper)-C may play a role in the advanced stages of the disease.
Activin A (zeige INHBA Antikörper), B, and AB have similar effects on steroidogenesis in human granulosa cells; in contrast, activin (zeige Actbeta Antikörper) AC is not biologically active and does not act as a competitive antagonist.
Serum inhibin levels correlate with clinical characteristics and mortality in epithelial ovarian cancer patients.
The inhibin-betaC subunit is down-regulated, while inhibin-betaE is up-regulated by interferon (zeige IFNA Antikörper)-beta1a in Ishikawa carcinoma cell line.
Single Nucleotide Polymorphisms in INHBC gene is associated with brain metastasis in non-small-cell lung cancer
Activin-beta (zeige Actbeta Antikörper)(C) is a regulator of activin-A (zeige INHBA Antikörper). Activin-beta (zeige Actbeta Antikörper)(C) is able to abolish cachexia and modulate reproductive tumour development in inhibin alpha-subunit (zeige INHA Antikörper) knockout mice (alpha-KO) mice.
inhibin-betaC in normal and pathological placental tissue was demonstrated, although no differences in staining intensity could be observed. Functional role of novel inhibin-betaC subunit in normal and pathological human placenta is still quite unclear.
Data show that inhibin A levels were significantly lower in the PCOS group compared to the control group, and inhibin B levels were comparable in the two groups.
the novel inhibin/activin (zeige Actbeta Antikörper)-betaC subunit is expressed in human endometrioid adenocarcinomas and in the human endometrial carcinoma cell line HEC (zeige NDC80 Antikörper)-1a
Expression of the inhibin betaC and betaE subunits was demonstrated at the protein level and at the transcriptional level in normal human endometrial tissue and in the Ishikawa human endometrial carcinoma cell line.
This gene encodes the beta C chain of inhibin, a member of the TGF-beta superfamily. This subunit forms heterodimers with beta A and beta B subunits. Inhibins and activins, also members of the TGF-beta superfamily, are hormones with opposing actions and are involved in hypothalamic, pituitary, and gonadal hormone secretion, as well as growth and differentiation of various cell types.
inhibin, beta C
, Activin beta-C chain
, activin beta-C chain
, activin/inhibin beta C
, inhibin beta C chain