CDX2 Proteine (CDX2)

Bezeichnung:
Caudal Type Homeobox 2 Proteine (CDX2)
Auf www.antikoerper-online.de finden Sie aktuell 5 Caudal Type Homeobox 2 (CDX2) Proteine von 4 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen CDX2 Antikörper (278) und CDX2 Kits (28) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 324 CDX2 Produkte verfügbar.
Synonyme:
Cdx-2, CDX-3, CDX2, CDX3, cdx3-like, MGC130987
alle Proteine anzeigen Gen GeneID UniProt
CDX2 66019  
CDX2 1045 Q99626
CDX2 12591 P43241

Weitere Synonyme anzeigen

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Weitere Proteine zu CDX2 Interaktionspartnern

Rhesus Monkey Caudal Type Homeobox 2 (CDX2) Interaktionspartner

  1. These results provide evidence that CDX2 plays an essential role in functional trophectoderm formation during primate embryonic development.

Human Caudal Type Homeobox 2 (CDX2) Interaktionspartner

  1. Cytapheresis might induce CDX2 expression without affecting the cell proliferation, thus resulting in mucosal healing with goblet cell restoration.

  2. SOX2 (zeige SOX2 Proteine) expression induces a cellular stem cell state in human colorectal cancer (CRC (zeige CALR Proteine)) with a decreased expression of CDX2. Furthermore, a down-regulated expression of CDX2 results in a poor patient prognosis in CRC (zeige CALR Proteine).

  3. A small subset (5%) of hepatocellular carcinomas are CDX2 positive.

  4. A new organ culture system for adult murine oesophagus is described. Using this, Cdx2 and HNF4alpha (zeige HNF4A Proteine) were ectopically expressed by adenoviral infection. We demonstrate the expression of CDX2 and HNF4alpha (zeige HNF4A Proteine) in human biopsy samples.

  5. Colon cancer cells expressing CDX2 are less deformable, a feature that has been shown to correlate with poor metastatic potential.

  6. Results show that CDX2 and Fbw7 expression is inversely correlated during colon cell differentiation and that CDX2 expression is regulated by Fbw7 in a GSK3b-dependent manner.

  7. Aberrant DNA methylation (zeige HELLS Proteine) of SOX2 (zeige SOX2 Proteine) and CDX2 genes contributes to the development of IM. Notably, SOX2 (zeige SOX2 Proteine) may play a role in establishing and maintaining the methylation status of the CDX2 gene in gastric tissues and cells.

  8. Strong expression of CDX2 was demonstrated only in the mature colonic epithelium of teratomas in both primary and metastatic germ cell tumors of the testis.

  9. Cdx (zeige CDX1 Proteine) members interact with the SWI (zeige SMARCA1 Proteine)-SNF (zeige SNRPA Proteine) complex and make direct contact with Brg1 (zeige SMARCA4 Proteine), a catalytic member of SWI (zeige SMARCA1 Proteine)-SNF (zeige SNRPA Proteine). Both Cdx2 and Brg1 (zeige SMARCA4 Proteine) co-occupy a number of Cdx (zeige CDX1 Proteine) target genes, and both factors are necessary for transcriptional regulation of such targets. Finally, Cdx2 and Brg1 (zeige SMARCA4 Proteine) occupancy occurs coincident with chromatin remodeling at some of these loci.

  10. we found that the loss of CDX2 expression in colorectal cancer is inversely related with the methylation of CDX2 promoter. The methylation of the CDX2 promoter was associated with enhanced lymph node metastases and shorter survival time ( p = 0.0273), but was independent of tumor stage, tumor differentiation, gender, and age.

Pig (Porcine) Caudal Type Homeobox 2 (CDX2) Interaktionspartner

  1. these results provide further insight into the functional diversity of CDX2 in early mammalian embryos.

  2. showed novel molecular regulation of CDX2 on Oct4 (zeige POU5F1 Proteine), and provided important clues for clarifying the mechanism of interaction between CDX2 and Oct4 (zeige POU5F1 Proteine) in embryo of mammals other than mouse

Mouse (Murine) Caudal Type Homeobox 2 (CDX2) Interaktionspartner

  1. A new organ culture system for adult murine oesophagus is described. Using this, Cdx2 and HNF4alpha (zeige HNF4A Proteine) were ectopically expressed by adenoviral infection. We demonstrate the expression of CDX2 and HNF4alpha (zeige HNF4A Proteine) in human biopsy samples.

  2. Cdx (zeige CDX1 Proteine) members interact with the SWI (zeige SMARCA1 Proteine)-SNF (zeige SNRPA Proteine) complex and make direct contact with Brg1 (zeige SMARCA4 Proteine), a catalytic member of SWI (zeige SMARCA1 Proteine)-SNF (zeige SNRPA Proteine). Both Cdx2 and Brg1 (zeige SMARCA4 Proteine) co-occupy a number of Cdx (zeige CDX1 Proteine) target genes, and both factors are necessary for transcriptional regulation of such targets. Finally, Cdx2 and Brg1 (zeige SMARCA4 Proteine) occupancy occurs coincident with chromatin remodeling at some of these loci.

  3. The authors identify a Cdx2-responsive segment of HoxA, immediately 5' to the recently defined regulatory domain orchestrating initial transcription of the first Hox (zeige MSH2 Proteine) gene.

  4. Cdx1 (zeige CDX1 Proteine)-Cdx2 double null mutants exhibited loss of primitive erythroblasts, aberrant vascular remodelling of the yolk sac (zeige ADCY10 Proteine) and a block in hematopoietic differentiation from yolk sac (zeige ADCY10 Proteine)-derived cells in culture.

  5. this study shows that Aloe vera (zeige IGF2BP3 Proteine) gel suppresses colitis-related colon carcinogenesis via increased expression of CDX-2, a tumor suppressor in colorectal cancer

  6. Results point out the complex interplay between the DSB DNA repair activity and the homeoproteins HoxB7 (zeige HOXB7 Proteine) and Cdx2 in colon cancer cells.

  7. CDX2 is required for proliferation and differentiation of intestinal stem cells. Direct CDX2 targets in ISCs (zeige NFS1 Proteine) may be activated or repressed.

  8. cells in preimplantation embryos that localized in an initial outer position initiated the expression of Cdx2. cells that changed their position from an outer to an inner position downregulated Cdx2 expression and contributed to the inner cell mass.

  9. findings illuminated a role for NOD1 (zeige NOD1 Proteine) signaling in attenuating H. pylori-induced Cdx2 expression in gastric epithelial cells

  10. Overexpression of CDX2 inhibits the growth of the gastric cancer cells in vivo and in vitro.

Cow (Bovine) Caudal Type Homeobox 2 (CDX2) Interaktionspartner

  1. results thus indicate that CDX2 is not required for TE formation during bovine development; nevertheless, it is necessary for maintaining TE integrity.

CDX2 Protein Überblick

Protein Überblick

This gene is a member of the caudal-related homeobox transcription factor gene family. The encoded protein is a major regulator of intestine-specific genes involved in cell growth an differentiation. This protein also plays a role in early embryonic development of the intestinal tract. Aberrant expression of this gene is associated with intestinal inflammation and tumorigenesis.

Alternative names and synonyms associated with CDX2

  • caudal type homeobox 2 (CDX2)
  • caudal type homeobox 2 (cdx2)
  • caudal type homeo box 2 (Cdx2)
  • caudal type homeobox 2 (Cdx2)
  • Cdx-2 Protein
  • CDX-3 Protein
  • CDX2 Protein
  • CDX3 Protein
  • cdx3-like Protein
  • MGC130987 Protein

Bezeichner auf Proteinebene für Caudal Type Homeobox 2 Proteine (CDX2)

caudal type homeobox 2 , caudal type homeobox transcription factor 2 , caudal type homeo box transcription factor 2 , homeobox protein CDX-2 , caudal-type homeobox protein 2 , caudal type homeo box 2 , caudal-type homeobox transcription factor 2

GENE ID SPEZIES
467350 Pan troglodytes
711094 Macaca mulatta
735025 Xenopus laevis
66019 Rattus norvegicus
1045 Homo sapiens
374205 Gallus gallus
486028 Canis lupus familiaris
100127132 Sus scrofa
12591 Mus musculus
618679 Bos taurus
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