anti-JAG1 (JAG1) Antikörper

Bezeichnung:
anti-Jagged 1 Antikörper (JAG1)
Auf www.antikoerper-online.de finden Sie aktuell 183 Jagged 1 (JAG1) Antikörper von 24 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen JAG1 Proteine (27) und JAG1 Kits (19) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 239 JAG1 Produkte verfügbar.
Synonyme:
ABE2, AGS, AHD, AWS, CD339, Gsfabe2, HJ1, Htu, JAG1, JAGL1, Ozz, Ser-1

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anti-Human JAG1 Antikörper:

anti-Rat (Rattus) JAG1 Antikörper:

anti-Mouse (Murine) JAG1 Antikörper:

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Am meisten referenzierte anti-JAG1 Antikörper

  1. Human Monoclonal JAG1 Primary Antibody für FACS - ABIN4900205 : Kibbie, Teles, Wang, Hong, Montoya, Krutzik, Lee, Kwon, Modlin, Cruz: Jagged1 Instructs Macrophage Differentiation in Leprosy. in PLoS pathogens 2016 (PubMed)
    Zeige alle 5 Referenzen für 4900205

  2. Mouse (Murine) Monoclonal JAG1 Primary Antibody für IHC (fro), FACS - ABIN2480076 : McKusick: The Human Genome Project and clinical medicine. in Hospital practice (Office ed.) 1991 (PubMed)
    Zeige alle 4 Referenzen für 2480076

  3. Dog (Canine) Monoclonal JAG1 Primary Antibody für IF, WB - ABIN968827 : Berezovska, Xia, Hyman: Notch is expressed in adult brain, is coexpressed with presenilin-1, and is altered in Alzheimer disease. in Journal of neuropathology and experimental neurology 1998 (PubMed)
    Zeige alle 4 Referenzen für 968827

  4. Human Polyclonal JAG1 Primary Antibody für EIA, FACS - ABIN951303 : Foldi, Chung, Xu, Zhu, Outtz, Kitajewski, Li, Hu, Ivashkiv: Autoamplification of Notch signaling in macrophages by TLR-induced and RBP-J-dependent induction of Jagged1. in Journal of immunology (Baltimore, Md. : 1950) 2010 (PubMed)
    Zeige alle 2 Referenzen für 951303

  5. Rat (Rattus) Polyclonal JAG1 Primary Antibody für ELISA (Capture), FACS - ABIN4900585 : Stahl, Uemura, Ge, Shi, Tashima, Stanley: Roles of Pofut1 and O-fucose in mammalian Notch signaling. in The Journal of biological chemistry 2008 (PubMed)
    Zeige alle 2 Referenzen für 4900585

  6. Human Polyclonal JAG1 Primary Antibody für FM, IHC - ABIN1043767 : Yabe, Matsumoto, Tsurumoto, Shindo: Immunohistological localization of Notch receptors and their ligands Delta and Jagged in synovial tissues of rheumatoid arthritis. in Journal of orthopaedic science : official journal of the Japanese Orthopaedic Association 2005 (PubMed)

  7. Human Polyclonal JAG1 Primary Antibody für ICC, IF - ABIN337168 : Siar, Ha, Aung, Nakano, Tsujigiwa, Nagatsuka, Ng, Kawakami: Immunolocalization of notch signaling protein molecules in a maxillary chondrosarcoma and its recurrent tumor. in European journal of medical research 2010 (PubMed)

  8. Human Polyclonal JAG1 Primary Antibody für ICC, IF - ABIN269362 : Okamoto, Matsuda, Joetham, Lucas, Domenico, Yasutomo, Takeda, Gelfand: Jagged1 on dendritic cells and Notch on CD4+ T cells initiate lung allergic responsiveness by inducing IL-4 production. in Journal of immunology (Baltimore, Md. : 1950) 2009 (PubMed)

Weitere Antikörper gegen JAG1 Interaktionspartner

Human Jagged 1 (JAG1) Interaktionspartner

  1. Results showed that JAG1 was significantly downregulated in miR (zeige MLXIP Antikörper)-26a-overexpressing osteosarcoma cells and is a direct target of miR (zeige MLXIP Antikörper)-26a.

  2. the effects of two Notch (zeige NOTCH1 Antikörper) ligands, i.e., Jagged1 and DLL1 (zeige DLL1 Antikörper), on murine and human hematopoiesis in vitro. Our observations indicate that the stromal expression of Notch (zeige NOTCH1 Antikörper) ligands increases the production of both the total and phenotypically early murine and human hematopoietic cells in the co-culture.

  3. Specific Notch3 (zeige NOTCH3 Antikörper) and Jag1 subcellular localization patterns may provide clues for the behavior of the corresponding tumors and could potentially be applied in the clinic for Jag1 targeting in triple-negative breast cancer patients.

  4. there is a cross-talk between Jagged1/Notch3 (zeige NOTCH3 Antikörper) and VEGF (zeige VEGFA Antikörper) in TNBC angiogenesis. Jagged1/Notch3 (zeige NOTCH3 Antikörper) is expected to be an important signaling pathway for TNBC progression and a potential target for TNBC neovascularization therapy.

  5. Low levels of Notch pathway genes Notch1, Notch2, Notch4 and Jagged1 correlated with poor prognostic factors such as larger tumor size, positive lymph-node status, tumor phenotype and infiltrating tumor Treg cells.

  6. Human Jagged-1 induced the proliferation and differentiation of CD133+ cord blood progenitors compared with hDll-1. Thus, hJagged-1 signaling in the bone marrow niche may be used to expand EPCs for therapeutic angiogenesis

  7. By studying leprosy as a model, we provide evidence that upregulation of JAG1 on endothelium instructs monocytes to differentiate into M1 macrophages with antimicrobial activity.

  8. High Jag1 expression is associated with metastasis in colorectal cancer.

  9. amplification of Jagged1 contributed to mRNA expression that activates the Jagged1-Notch (zeige NOTCH1 Antikörper) signaling pathway in liver cancer and led to poor outcome.

  10. Our data revealed that MALAT1 inhibited tongue cancer cell growth and metastasis through miR-124-dependent JAG1 regulation. In conclusion, we revealed that MALAT1 may play an oncogenic role by increasing proliferation and metastasis of tongue cancer and is a potential therapeutic target in human tongue cancer.

Mouse (Murine) Jagged 1 (JAG1) Interaktionspartner

  1. the effects of two Notch (zeige NOTCH1 Antikörper) ligands, i.e., Jagged1 and DLL1 (zeige DLL1 Antikörper), on murine and human hematopoiesis in vitro. Our observations indicate that the stromal expression of Notch (zeige NOTCH1 Antikörper) ligands increases the production of both the total and phenotypically early murine and human hematopoietic cells in the co-culture.

  2. Fringe modifications at EGF8 and EGF12 enhanced Notch1 binding to and activation from Delta-like 1, while modifications at EGF6 and EGF36 (added by Manic and Lunatic but not Radical) inhibited Notch1 activation from Jagged1.

  3. A Jagged1-Hey1 (zeige HEY1 Antikörper) signal might mediate the impairment of angiogenesis induced by Ang II (zeige AGT Antikörper) during cardiac hypertrophy.

  4. Data show that Rac1 induced nuclear import of STAT3 (zeige STAT3 Antikörper) by physical binding, and nuclear STAT3 (zeige STAT3 Antikörper) directly activated the transcription of essential oocyte-specific genes, including Jagged1, GDF9 (zeige GDF9 Antikörper) and BMP15 (zeige BMP15 Antikörper).

  5. Diabetes mellitus induces Jagged1 overexpression and suppresses Notch signaling in endothelial cells. Blocking Jagged1 prevented diabetes-induced microvasculopathy and could reverse it even after 4 weeks.

  6. Jagged1 intracellular domain-mediated inhibition of Notch1 (zeige NOTCH1 Antikörper) signalling regulates cardiac homeostasis in the postnatal heart.

  7. endothelial Jagged1 has a role in promoting solid tumor development

  8. Jag1 expression in pulmonary capillary endothelial cells is upregulated after repeated lung injury and contributes to lung fibrosis.

  9. On a C57BL/6 background, Jag1 haploinsufficiency results in bile duct paucity in mice

  10. Jag1-induced Notch (zeige NOTCH1 Antikörper) activity and the subsequent (or concomitant) downregulation of the Dll4 (zeige DLL4 Antikörper)-mediated signalling are both required for generating haematopoietic stem cells in the embryo.

JAG1 Antigen-Profil

Beschreibung des Gens

The jagged 1 protein encoded by JAG1 is the human homolog of the Drosophilia jagged protein. Human jagged 1 is the ligand for the receptor notch 1, the latter a human homolog of the Drosophilia jagged receptor notch. Mutations that alter the jagged 1 protein cause Alagille syndrome. Jagged 1 signalling through notch 1 has also been shown to play a role in hematopoiesis.

Alternative names and synonyms associated with JAG1

  • jagged 1 (JAG1) Antikörper
  • jagged 1 (jag1) Antikörper
  • jagged 1 (Jag1) Antikörper
  • ABE2 Antikörper
  • AGS Antikörper
  • AHD Antikörper
  • AWS Antikörper
  • CD339 Antikörper
  • Gsfabe2 Antikörper
  • HJ1 Antikörper
  • Htu Antikörper
  • JAG1 Antikörper
  • JAGL1 Antikörper
  • Ozz Antikörper
  • Ser-1 Antikörper

Bezeichner auf Proteinebene für anti-Jagged 1 (JAG1) Antikörper

jagged 1 (Alagille syndrome) , jagged 1 , protein jagged-1-like , protein jagged-1 , Serrate-1

GENE ID SPEZIES
718580 Macaca mulatta
780486 Ovis aries
100474031 Ailuropoda melanoleuca
100486874 Xenopus (Silurana) tropicalis
100547052 Meleagris gallopavo
100566281 Anolis carolinensis
182 Homo sapiens
29146 Rattus norvegicus
16449 Mus musculus
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