Use your antibodies-online credentials, if available.
Keine Produkte auf Ihrer Vergleichsliste.
Ihr Warenkorb ist leer.
Alle Spezies anzeigen
Weitere Synonyme anzeigen
Select your species
Findings indicate that RE1 (zeige NPC2 ELISA Kits) silencing transcriptional factor (REST) regulates its miR (zeige MLXIP ELISA Kits)-124 and mir (zeige MLXIP ELISA Kits)-203 gene and suggest how REST maintains oncogenic competence in glioblastoma (GBM)stem cells. These mechanisms could potentially be utilized to block REST-mediated GBM tumorigenesis.
findings indicate that SCYL1 (zeige CCL13 ELISA Kits) does not contribute to REST turnover and thus do not support a previous study suggesting a role for SCYL1 (zeige CCL13 ELISA Kits) in mediating REST degradation
the mechanisms of inhibition of the small-molecule drugs 4SC-202 and SP2509 were analyzed. These drugs interfered with the viability of medulloblastoma cells, where REST/NRSF has been implicated in cancer pathogenesis. Thus, a resource for molecular REST/NRSF studies and drug development has been established.
Expressions of REST and RCOR1 (zeige RCOR1 ELISA Kits) genes may downregulate SYN1 (zeige SYN1 ELISA Kits) expression in gliomas.
REST represses transcription of HIF-1alpha (zeige HIF1A ELISA Kits) in prolonged hypoxia, thus contributing to the resolution of the HIF-1alpha (zeige HIF1A ELISA Kits) response.
A role was determined for the NRSF-BDNF (zeige BDNF ELISA Kits) pathway in the modulation of cognitive function in patients with newly diagnosed epilepsy.
The splicing of REST by SRRM4 (zeige SRRM4 ELISA Kits) could promote the neuroendocrine phenotype in CRPC.
TSPYL2 (zeige TSPYL2 ELISA Kits) is an essential component of the REST/NRSF transcriptional complex for TGFbeta (zeige TGFB1 ELISA Kits) signaling activation
Cultured astrocytes gradually became refractory to reprogramming, in part by the repressor REST preventing Neurog2 (zeige NEUROG2 ELISA Kits) from binding to the NeuroD4 (zeige NEUROD4 ELISA Kits) promoter.
identified and validated a novel promoter of the MIR137 gene adjacent to miR (zeige MLXIP ELISA Kits)-137 itself which can direct the expression of distinct mRNA isoforms encoding miR (zeige MLXIP ELISA Kits)-137; internal promoter is regulated by repressor element-1 silencing transcription factor (REST)
Findings provide evidence for the loss of globin-linked neuroprotection to be linked to Alzheimer's disease angiopathogenesis, while raising the possibility of REST/ NRSF being an upstream regulator.
a new paradigm of transcriptional regulation critical for cardiac development and maturation that is controlled by the interaction of REST, DNMT3B (zeige DNMT3B ELISA Kits) and non-CpG methylation.
Data indicate that levels of repressor element-1 silencing transcription factor (REST) are elevated in polyubiquitin-B (zeige UBB ELISA Kits) knockout (Ubb (zeige UBA52 ELISA Kits) -/-) cells.
Results identified REST as a novel target gene that was negatively regulated by miR (zeige MLXIP ELISA Kits)-218 in cardiomyocytes hypertrophy process.
Detailed analysis of specific lineage markers expression showed selective downregulation of endoderm markers in REST-null cells, thus contributing to a loss of cardiogenic signals. REST regulates cardiac differentiation of ESCs (zeige NR2E3 ELISA Kits) by negatively regulating the Wnt (zeige WNT2 ELISA Kits)/beta-catenin (zeige CTNNB1 ELISA Kits) signaling pathway and positively regulating the cardiogenic TF Gata4 (zeige GATA4 ELISA Kits)
The transcriptional repressor REST represses miR (zeige MLXIP ELISA Kits)-21 and, thus, regulates self-renewal in E14Tg2a.4 mESCs cultured in the absence of mouse embryonic fibroblast feeder cell effects.
Data suggest that Rest regulates early osteoblast differentiation via modulating Rest expression that is independent of Osx (zeige SP7 ELISA Kits) expression.
REST expression in nerve injury is decreased following alternative splicing which in turn controls PACAP (zeige ADCYAP1 ELISA Kits) expression.
We propose a mechanism for transcriptional activation in neurons that involves REST-guided targeting of TET3 (zeige TET3 ELISA Kits) to the DNA for directed 5hmC generation and NSD3 (zeige WHSC1L1 ELISA Kits)-mediated H3K36 trimethylation
This study demostrated that maternal rest plays a long-term role in regulation of gene expression through snap25a/b and behavior during development.
The transcriptional repressor rest modulates hedgehog (zeige SHH ELISA Kits) signaling.
This gene encodes a transcriptional repressor that represses neuronal genes in non-neuronal tissues. It is a member of the Kruppel-type zinc finger transcription factor family. It represses transcription by binding a DNA sequence element called the neuron-restrictive silencer element. The protein is also found in undifferentiated neuronal progenitor cells and it is thought that this repressor may act as a master negative regular of neurogenesis. Alternatively spliced transcript variants have been described
neural-restrictive silencer factor
, neuron restrictive silencer factor
, repressor binding to the X2 box
, zinc finger transcription factor REST protein
, RE1-silencing transcription factor
, RE-1 silencer of transcription