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Data indicate angiopoietin-like 4 (ANGPTL4 (zeige ANGPTL4 ELISA Kits)) as a key player that coordinates an increase in cellular energy flux crucial for EMT (zeige ITK ELISA Kits) via an ANGPTL4 (zeige ANGPTL4 ELISA Kits)/14-3-3gamma signaling axis.
14-3-3gamma regulates the differentiation ability of CPNE1 (zeige CPNE1 ELISA Kits) through the binding with C2A domain of CPNE1 (zeige CPNE1 ELISA Kits) in HiB5 cells.
YWHAG de novo mutations cause early onset epilepsy, including epileptic encephalopathies and intellectual disability.
Study found that the overexpression of 14-3-3gamma in utero in the developing mouse cortex results in delays in pyramidal neuron migration.
The present study revealed the tumor suppressive role of miR (zeige MLXIP ELISA Kits)-509-5p in non-small cell lung cancer (NSCLC) by targeting YWHAG, suggesting that miR (zeige MLXIP ELISA Kits)-509-5p/YWHAG axis might be considered as a novel and potential target for clinical diagnosis and therapeutics of NSCLC.
14-3-3 protein (zeige YWHAE ELISA Kits) expression was quantitatively analyzed in cerebrospinal fluid of 231 sporadic Creutzfeldt-Jakob disease and 2035 control patients.
Data suggest that miR (zeige MLXIP ELISA Kits)-181b-3p functions as a metastasis activator by promoting Snail (zeige SNAI1 ELISA Kits)-induced epithelial-mesenchymal transition in breast cancer cells by directly targeting YWHAG.
Loss of p53 (zeige TP53 ELISA Kits) function may result in upregulation of 14-3-3gamma in lung cancers
Changes for CRMP2 (zeige DPYSL2 ELISA Kits), TCP1epsilon, TPM2 (zeige TPM2 ELISA Kits) and 14-3-3gamma were confirmed in experimental tumors and in a series of 28 human SI-NETs.
These results showed that the cell surface expression of TRPM4 (zeige TRPM4 ELISA Kits) channels is mediated by 14-3-3gamma binding.
This study found that in utero 14-3-3gamma-deficiency resulted in delays in neuronal migration as well as morphological defects.
Protein kinase CK2 (zeige CSNK2A1 ELISA Kits) interacts at the neuromuscular synapse with Rapsyn (zeige RAPSN ELISA Kits), Rac1, 14-3-3gamma, and Dok-7 (zeige DOK7 ELISA Kits) proteins and phosphorylates the latter two.
Ser (zeige SIGLEC1 ELISA Kits)(58) phosphorylation and Lys (zeige LYZ ELISA Kits)(49) acetylation of 14-3-3gamm occur in a coordinated time-dependent manner to regulate 14-3-3gamma homodimerization.
hypoxia can activate p53 (zeige TP53 ELISA Kits) through inactivation of MDMX (zeige MDM4 ELISA Kits) by the ATR (zeige ATR ELISA Kits)-Chk1 (zeige CHEK1 ELISA Kits)-MDMX (zeige MDM4 ELISA Kits)-14-3-3gamma pathway.
Data show that binding motifs of 14-3-3gamma were identified in components of the transduceosome, including STAR.
overexpression of 14-3-3gamma led to resistance to both rotenone and 1-methyl-4-phenylpyridinium (MPP(+)), while other isoforms were not protective against both toxins.
a new role for 14-3-3gamma in protecting p21 from MDMX (zeige MDM4 ELISA Kits)-mediated proteasomal turnover, which may partially account for DNA damage-induced elevation of p21 levels independent of p53 (zeige TP53 ELISA Kits).
Studies establish 14-3-3gamma as an oncogene (zeige RAB1A ELISA Kits) and implicate MAPK (zeige MAPK1 ELISA Kits) and PI3K signaling as important for 14-3-3gamma induced transformation.
Data suggest that 14-3-3 (zeige YWHAQ ELISA Kits) regulates LRRK2 (zeige LRRK2 ELISA Kits) and that disruption of the interaction of LRRK2 (zeige LRRK2 ELISA Kits) with 14-3-3 (zeige YWHAQ ELISA Kits) may be linked to Parkinson's disease.
molecular network including eIF1AX (zeige EIF1AY ELISA Kits), RPS7 (zeige RPS7 ELISA Kits), and 14-3-3gamma regulates protein translation and cell proliferation in BMECs.
This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 100% identical to the rat ortholog. It is induced by growth factors in human vascular smooth muscle cells, and is also highly expressed in skeletal and heart muscles, suggesting an important role for this protein in muscle tissue. It has been shown to interact with RAF1 and protein kinase C, proteins involved in various signal transduction pathways.
, tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide
, 14-3-3 protein gamma-1
, 14-3-3 protein gamma
, protein kinase C inhibitor protein 1
, 14-3-3 protein gamma subtype
, 3-monooxgenase/tryptophan 5-monooxgenase activation protein, gamma polypeptide
, 3-monooxgenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide
, 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide
, scavenger receptor cysteine rich domain containing, group B (4 domains)
, 14-3-3 protein gamma-subtype
, 3-monooxygenase/tryptophan 5-monooxgenase activation protein gamma polypeptide
, tryosine 3-monooxgenase/tryptophan 5 monooxgenase activation protein gamma
, tryosine 3-monooxgenase/tryptophan 5-monooxgenase activation protein gamma polypeptide
, tyrosine 3-monooxgenase/tryptophan 5-monooxgenase activation protein, gamma polypeptide
, tyrosine 3/tryptophan 5 -monooxygenase activation protein gamma polypeptide
, tyrosine 3/tryptophan 5 -monooxygenase activation protein, gamma polypeptide