SLC8A1 Proteine (SLC8A1)

Solute Carrier Family 8 (Sodium/calcium Exchanger), Member 1 Proteine (SLC8A1)
Auf finden Sie aktuell 4 Solute Carrier Family 8 (Sodium/calcium Exchanger), Member 1 (SLC8A1) Proteine von 1 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen SLC8A1 Antikörper (48) und SLC8A1 Kits (18) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 74 SLC8A1 Produkte verfügbar.
AI852629, AV344025, D930008O12Rik, Enx, Hox11L.1, Hox11l1, NCX, Ncx1, ncx1n, SLC8A1, Tlx1l1, Tlx1l2
alle Proteine anzeigen Gen GeneID UniProt
SLC8A1 6546 P32418
Ratte SLC8A1 SLC8A1 29715 Q01728
SLC8A1 20541 P70414

Weitere Synonyme anzeigen

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Weitere Proteine zu SLC8A1 Interaktionspartnern

Human Solute Carrier Family 8 (Sodium/calcium Exchanger), Member 1 (SLC8A1) Interaktionspartner

  1. CaSR (zeige CASR Proteine) exerts a suppressive function in pancreatic tumorigenesis through a novel NCX1/Ca(2 (zeige CA2 Proteine)+)/beta-catenin (zeige CTNNB1 Proteine) signaling pathway.

  2. Palmitoylation of cardiac NCX1 can modify its function, physical interactions, and removal from the sarcolemma by domain-dependent endocytosis.

  3. NCX1 and the calcium binding protein (zeige CETN1 Proteine) calretinin (zeige CALB2 Proteine) cooperate within the striatum to confer tolerance against cerebral ischemia.

  4. ADD2 (zeige ADD2 Proteine) and NCX1 variants influence the risk and the clinical features of systemic lupus erythematosus and lupus nephritis.

  5. NCX1 operating in reverse mode plays a prominent role in calcium cytosolic regulation in highly metastatic melanoma cells.

  6. The expression of miR (zeige MLXIP Proteine)-206 by HUVECs reduced exosome production by regulating ADP-Ribosylation Factor 6 (ARF6 (zeige ARF6 Proteine)) and sodium/calcium exchanger 1 (NCX1).

  7. interaction of NHE1 (zeige SLC9A1 Proteine), NCX1 and CaM (zeige CALM1 Proteine) mediates the effects of IL6 (zeige IL6 Proteine) on human hepatocellular carcinoma

  8. NCX1.3 is the predominant NCX (zeige TLX2 Proteine) variant in the distal convoluted and connecting tubules tubules

  9. results demonstrate that CaM (zeige CALM1 Proteine) senses changes in [Ca2 (zeige CA2 Proteine)+]i and binds to the cytoplasmic loop of NCX1 to regulate exchange activity.

  10. The expressions of NCX1 and NCKX4 (zeige Slc24a4 Proteine) were significantly higher in the patent ductus arteriosus group at both the protein and mRNA levels.

Rabbit Solute Carrier Family 8 (Sodium/calcium Exchanger), Member 1 (SLC8A1) Interaktionspartner

  1. The SOCE/Cl(Ca) interaction does not require reverse-mode Na+/Ca2 (zeige CA2 Proteine)+ exchange in our conditions.

  2. There were substantial transmural gradients in Cav1.2, KChIP2, ERG, KvLQT1, Kir2.1, NCX1, SERCA2a and RyR2 at the mRNA and, in some cases, protein level-in every case the mRNA or protein was more abundant in the epicardium than the endocardium.

Guinea Pig Solute Carrier Family 8 (Sodium/calcium Exchanger), Member 1 (SLC8A1) Interaktionspartner

  1. NCX is an important determinant for premature ventricular activity in a drug-induced model of Andersen-Tawil syndrome.

Mouse (Murine) Solute Carrier Family 8 (Sodium/calcium Exchanger), Member 1 (SLC8A1) Interaktionspartner

  1. NCX1 is dispensable for osteoclast differentiation.

  2. the functional role of NCX on gastrointestinal motility

  3. These results suggested that NCX1 may play an important role in the proper spatial distribution of LTCC and JP2 (zeige JPH2 Proteine) in T-tubules in the context of pressure-overloading.

  4. In this study, authors demonstrate that NCX1 regulates gastric fundus motility.

  5. NCX1 and NCX2 play important roles in ileal motility and suggest that NCX1 and NCX2 regulate the motility in the ileum by controlling the sensitivity of smooth muscles to ACh (zeige FGFR3 Proteine) and SP.

  6. Data show that transforming growth factor beta1 (TGFbeta1 (zeige TGFB1 Proteine)) is a powerful stimulator of both, store operated Ca2 (zeige CA2 Proteine)+ entry (SOCE) and Na+/Ca2+-exchanger activity in megakaryocytes.

  7. dobutamine upregulates of voltage-gated Na+ channel function and Na+ influx-induced activation of the reverse mode of NCX

  8. JAK3 (zeige JAK3 Proteine) deficiency is followed by down-regulation of cytosolic Ca(2 (zeige CA2 Proteine)+) release, receptor and store operated Ca(2 (zeige CA2 Proteine)+) entry and Na(+)/Ca(2 (zeige CA2 Proteine)+) exchanger activity in dendritic cells.

  9. Results suggested that down-regulation of hippocampal NCX1 expression is associated with pentylenetetrazole-induced kindling seizure development

  10. TRPC3 (zeige TRPC3 Proteine)-NCX micro/nanodomain communication as determinant of cardiac contractility and susceptibility to arrhythmogenic stimuli.

Cow (Bovine) Solute Carrier Family 8 (Sodium/calcium Exchanger), Member 1 (SLC8A1) Interaktionspartner

  1. These results indicate that, for a proper MgATP up-regulation of NCX1, the enzyme responsible for PtdIns-4,5P2 synthesis must be (i) functionally competent and (ii) set in the NCX1 microenvironment closely associated to the exchanger.

  2. The cleavage of NCX1 by m-calpain (zeige CAPN2 Proteine) in the caveolae vesicles may be interpreted as an important mechanism of Ca(2 (zeige CA2 Proteine)+) overload

  3. a novel mechanism for the regulation of NCX1 activity

  4. Na/Ca exchanger's (NCX1) associates specifically with caveolin-3 (zeige CAV3 Proteine)(NCX1)(caveolin-3 (zeige CAV3 Proteine))

  5. the regulation of phosphatidylinositol-4,5-biphosphate binding to the bovine cardiac Na+/Ca2+ exchanger(NCX1)

  6. Data suggest that peroxynitrite leads to calcium (Ca2 (zeige CA2 Proteine)+) uptake through stimulation of Ca2+-ATPase, but inhibits Ca2 (zeige CA2 Proteine)+ uptake through inhibition of the sodium-Ca2 (zeige CA2 Proteine)+ exchanger, resulting in decreased overall Ca2 (zeige CA2 Proteine)+ uptake in smooth muscle microsomes.

  7. These data suggest a role for the reverse mode of the NCX in refilling the sarcoplasmic reticulum in airway smooth muscle following Ca(2 (zeige CA2 Proteine)+) mobilization.

  8. Cleavage of NCX may be interpreted as the main cause of Ca(2 (zeige CA2 Proteine)+) overload and could lay a key role in activation of apoptotic processes in pulmonary smooth muscle.

SLC8A1 Protein Überblick

Protein Überblick

In cardiac myocytes, Ca(2+) concentrations alternate between high levels during contraction and low levels during relaxation. The increase in Ca(2+) concentration during contraction is primarily due to release of Ca(2+) from intracellular stores. However, some Ca(2+) also enters the cell through the sarcolemma (plasma membrane). During relaxation, Ca(2+) is sequestered within the intracellular stores. To prevent overloading of intracellular stores, the Ca(2+) that entered across the sarcolemma must be extruded from the cell. The Na(+)-Ca(2+) exchanger is the primary mechanism by which the Ca(2+) is extruded from the cell during relaxation. In the heart, the exchanger may play a key role in digitalis action. The exchanger is the dominant mechanism in returning the cardiac myocyte to its resting state following excitation.

Alternative names and synonyms associated with SLC8A1

  • solute carrier family 8 (sodium/calcium exchanger), member 1 (SLC8A1)
  • solute carrier family 8 (sodium/calcium exchanger), member 1b (slc8a1b)
  • sodium/calcium exchanger 1 (Tsp_07038)
  • solute carrier family 8 (sodium/calcium exchanger), member 1 (Slc8a1)
  • T cell leukemia, homeobox 2 (Tlx2)
  • AI852629 Protein
  • AV344025 Protein
  • D930008O12Rik Protein
  • Enx Protein
  • Hox11L.1 Protein
  • Hox11l1 Protein
  • NCX Protein
  • Ncx1 Protein
  • ncx1n Protein
  • SLC8A1 Protein
  • Tlx1l1 Protein
  • Tlx1l2 Protein

Bezeichner auf Proteinebene für SLC8A1

solute carrier family 8 (sodium/calcium exchanger), member 1 , sodium/calcium exchanger 1 , ncx1b , sodium calcium exchanger 1n , sodium/calcium exchanger 1-like , Na(+)/Ca(2+)-exchange protein 1 , Na+/Ca++ exchanger , Na+/Ca2+ exchanger , sodium/calcium exchanger , solute carrier family 8 member 1 , Na/Ca exchanger , Na-Ca exchanger , solute carrier family 8, member 1 , sodium-calcium exchanger , sodium/calcium exchanger isoform NaCa13 , sodium/calcium exchanger isoform NaCa3 , sodium/calcium exchanger isoform NaCa9 , sodium/calcium exchanger isoform NaCa7 , PMUR10F , T-cell leukemia homeobox protein 2 , T-cell leukemia, homeobox 2 , enteric neuron homeobox protein , homeo box 11-like 1 , homeobox TLX-2 , homeobox protein Hox-11L1

470358 Pan troglodytes
797199 Danio rerio
10903331 Trichinella spiralis
100074200 Ornithorhynchus anatinus
100172867 Pongo abelii
100412198 Callithrix jacchus
6546 Homo sapiens
493808 Canis lupus familiaris
100328570 Oryctolagus cuniculus
29715 Rattus norvegicus
100135620 Cavia porcellus
20541 Mus musculus
395760 Gallus gallus
337925 Bos taurus
493807 Felis catus
475738 Canis lupus familiaris
21909 Mus musculus
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