PPARG Proteine (PPARG)

Bezeichnung:
Peroxisome Proliferator-Activated Receptor gamma Proteine (PPARG)
Auf www.antikoerper-online.de finden Sie aktuell 46 Peroxisome Proliferator-Activated Receptor gamma (PPARG) Proteine von 15 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen PPARG Antikörper (314) und PPARG Kits (74) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 451 PPARG Produkte verfügbar.
Synonyme:
CIMT1, GLM1, NR1C3, PPAR-GAMMA, PPAR-gamma2, PPARG, PPARG1, PPARG2, PPAR gamma, PPARGAMMA, PPARgamma2, xPPAR-gamma
alle Proteine anzeigen Gen GeneID UniProt
PPARG 19016 P37238
PPARG 5468 P37231
PPARG 25664 O88275

Weitere Synonyme anzeigen

PPARG Proteine (PPARG) nach Spezies

Wählen Sie die gewünschte Spezies

Am meisten referenzierte PPARG Proteine

  1. Human PPARG Protein expressed in Escherichia coli (E. coli) - ABIN667157 : Berger, Moller: The mechanisms of action of PPARs. in Annual review of medicine 2002 (PubMed)
    Zeige alle 2 Referenzen für 667157

Weitere Proteine zu PPARG Interaktionspartnern

Mouse (Murine) Peroxisome Proliferator-Activated Receptor gamma (PPARG) Interaktionspartner

  1. Tfe3 (zeige TFE3 Proteine) and Tfeb (zeige TFEB Proteine) are required for the induced expression of Ppargamma2 and subsequently for adipogenic genes.

  2. studies in humans and mice reveal that Akt2 (zeige AKT2 Proteine) controls hepatic tumorigenesis through crosstalk between HNF1alpha (zeige HNF1A Proteine) and PPARgamma.

  3. This work establishes PPARgamma as a required metabolic sensor and transcriptional regulator of repair macrophages and establishes GDF3 (zeige GDF3 Proteine) as a secreted extrinsic effector protein acting on myoblasts and serving as an exclusively macrophage-derived regeneration factor in tissue repair

  4. A high fat diet remodels PPARG genome-wide binding in visceral fat of mice.

  5. Data indicate that that M2 microglia supernatant can activate the peroxisome proliferator activated receptor gamma (PPARgamma) signaling pathway and promote neurogenesis and oligodendrogenesis from neural stem/progenitor cells (NSPCs) differentiation.

  6. Data, including data from studies using knockout/transgenic mice, suggest that PrPC (zeige PRNP Proteine) is involved in development of insulin (zeige INS Proteine) resistance and obesity; expression of PPARgamma is reduced in PrPC (zeige PRNP Proteine) knockout mice and increased in transgenic mice overexpressing PrPC (zeige PRNP Proteine). (PrPC (zeige PRNP Proteine) = cellular prion protein (zeige PRNP Proteine); PPARgamma = peroxisome proliferator-activated receptor gamma)

  7. PPARgamma deficiency causes cystic adenomatoid malformations in mouse fetal lung.

  8. endogenous cyclopentenone prostaglandins , produced by mice maintained on selenium-supplemented diets, alleviate the symptoms of CML through their ability to activate PPARgamm

  9. Aged Pparg null-mice present an anti-phospholipid syndrome , characterized by the late appearance of microthrombi and a mesangioproliferative pattern of glomerular injury, associated with significant plasmatic levels of anti-beta2- glycoprotein1 antibodies and renal deposition of IgG, IgM, and C3.

  10. knockdown of MKL1 induces a significant increase in the transcriptional activity of PPARgamma target genes and MKL1 interacts with PPARg, suggesting that SRF and MKL1 independently inhibit brown adipogenesis and that MKL1 exerts its effect mainly by modulating PPARgamma activity

Human Peroxisome Proliferator-Activated Receptor gamma (PPARG) Interaktionspartner

  1. Analysis of the PPARG gene in families with familial partial lipodystrophy

  2. These data demonstrate that complex of PPARgamma with GW1929 is a negative regulator involved in the control of ApoA-I (zeige APOA1 Proteine) expression and secretion in human hepatocyte- and enterocyte-like cells

  3. The Adiponectin (zeige ADIPOQ Proteine) increases AQP3 (zeige AQP3 Proteine) expression through PPARalpha (zeige PPARA Proteine)-mediated signaling inhepatic stellate cells.

  4. studies in humans and mice reveal that Akt2 (zeige AKT2 Proteine) controls hepatic tumorigenesis through crosstalk between HNF1alpha (zeige HNF1A Proteine) and PPARgamma.

  5. In this study, we found that rs1805192 alleles and genotypes of the PPAR-gamma gene were associated with Systemic lupus erythematosus risk.

  6. we performed a candidate-gene association study in a young and sportive Italian population by testing the association of functional polymorphisms in ACE (zeige ACE Proteine) (rs4646994), FTO (zeige FTO Proteine) (rs9939609), MC4R (zeige MC4R Proteine) (rs17782313) and PPARG (rs1801282) genes with body mass index (BMI) and waist-to-height ratio (WHtR).

  7. Missense variant in PPARG is associated with lipodystrophy and type 2 diabetes.

  8. High PPARgamma expression is associated with Acute Monocytic Leukemia (zeige KAT6B Proteine).

  9. Data indicate that MMP1 (zeige MMP1 Proteine), MMP12 (zeige MMP12 Proteine) and PPARG and hsa (zeige CD24 Proteine)-miR (zeige MLXIP Proteine)-31-5p, hsa (zeige CD24 Proteine)-miR (zeige MLXIP Proteine)-224-5p, and hsa (zeige CD24 Proteine)-miR (zeige MLXIP Proteine)-223-3p were able to distinguish tumors from NPT with high sensitivity and specificity.

  10. The immunoprecipitation results also showed that high AA concentrations significantly increased the interaction of mTOR (zeige FRAP1 Proteine) and PPARg. In summary, PPARg plays an important role in the regulation of IGF-1 (zeige IGF1 Proteine) secretion and gene expression in response to dietary protein.

Pig (Porcine) Peroxisome Proliferator-Activated Receptor gamma (PPARG) Interaktionspartner

  1. The immunoprecipitation results also showed that high AA concentrations significantly increased the interaction of mTOR (zeige FRAP1 Proteine) and PPARg. In summary, PPARg plays an important role in the regulation of IGF-1 (zeige IGF1 Proteine) secretion and gene expression in response to dietary protein.

  2. The regulatory role of microRNA miR (zeige MYLIP Proteine)-27b-3p on peroxisome proliferator-activated receptor-gamma (PPARgamma) was confirmed by their inversed expression patterns in oocytes: [miR (zeige MYLIP Proteine)-27b-3p]

  3. an Enhancer box and a binding site for a cooperative co-activator of MyoD (zeige MYOD1 Proteine) are present in the promoter region of porcine PPARgamma.

  4. The data suggest that there is local cooperation between resistin (zeige RETN Proteine) and PPARgamma expression in the porcine ovary. Resistin (zeige RETN Proteine) significantly increased the expression of PPARgamma, whereas PPARgamma decreased resistin (zeige RETN Proteine) expression; thus, PPARgamma is a new key regulator of resistin (zeige RETN Proteine) expression and function.

  5. Therefore, this study demonstrated that the different regulatory adipogenic roles of MSTN (zeige MSTN Proteine) in ADSCs and MSCs act by differentially regulating PPARgamma and MyoD (zeige MYOD1 Proteine) expression.

  6. PGRN (zeige GRN Proteine) inhibits adipogenesis in porcine preadipocytes partially through ERK (zeige MAPK1 Proteine) activation mediated PPARgamma phosphorylation.

  7. Resveratrol activated sirtuin 1 (Sirt1 (zeige SIRT1 Proteine)) gene expression and increased adipose triglyceride lipase (ATGL (zeige PNPLA2 Proteine)) gene expression and glycerol release. Furthermore, this study found the opposite Sirt1 (zeige SIRT1 Proteine) regulation pattern for PPARgamma to that of ATGL (zeige PNPLA2 Proteine) in adipocytes.

  8. The results indicate that the endometrial expression of PPARgamma genes fluctuates during the estrous cycle and pregnancy.

  9. Increasing dietary DE linearly enhanced the expression of PPARgamma in adipose tissues but not skeletal muscle of Rongchang piglets.

  10. These results suggest that trans-10, cis (zeige CISH Proteine)-12-conjugated linoleic acid can modulate TNF-alpha (zeige TNF Proteine) production and NF-kappa B (zeige NFKB1 Proteine) expression by a PPARgamma-dependent pathway in porcine peripheral blood mononuclear cells.

Cow (Bovine) Peroxisome Proliferator-Activated Receptor gamma (PPARG) Interaktionspartner

  1. PPARgamma is a positive regulator of milk fat synthesis in dairy cow mammary epithelial cells.

  2. An Asp7Gly substitution in PPARG is associated with adiposity.

  3. upregulation of PPARgamma was observed in the backfat tissue of Lilu cattle with increasing age

  4. Co-culture of adipocytes and myoblasts elicited an increase in C/EBPbeta (zeige CEBPB Proteine) and PPAR-gamma gene expression in differentiated myoblasts and an increase in GPR43 (zeige FFAR2 Proteine) gene expression in adipocytes.

  5. A potential association of an single nucleotide polymorphism (72472 GT in exon7) of the bovine PPAR-gamma gene with carcass and meat quality traits, was evaluated.

  6. study demonstrates the co-expression of DLX3 (zeige DLX3 Proteine), PPARG and SP1 (zeige SP1 Proteine) in trophoblast binucleated cell(BNC)nuclei; this suggests a possible role of these transcription factors through BNC specific genes at the time of pre-placental differentiation

  7. Single nucleotide polymorphisms in coding region of the PPARgamma gene, were examined.

  8. oxidative stress attenuates PPAR gamma expression and activity in vascular endothelial cells

  9. The effects of dietary fat components on the expression of PPAR-gamma AND PPAR-gamma coactivator 1 in cultured bovine preadipocytes are reported.

  10. Intramammary infection elicited a strong transcriptomic response, leading to potent activation of pro-inflammatory pathways that were associated with a marked inhibition of lipid synthesis, stress-activated kinase signaling cascades, and PPAR (zeige PPARA Proteine) signaling.

Rhesus Monkey Peroxisome Proliferator-Activated Receptor gamma (PPARG) Interaktionspartner

  1. study found PPAR-gamma expression was prominent in the subthalamic nucleus, oculomotor nucleus, ventral tegmental nucleus, and to a lesser extent, in the putamen; 3 or 12 months after MPTP (zeige PTPN2 Proteine), only the lesioned putamen had increased PPAR-gamma

  2. Aleglitazar, a dual PPARalpha (zeige PPARA Proteine)/gamma agonist, has beneficial effects on both lipid and glucose parameters in a primate model of the metabolic syndrome.

Rabbit Peroxisome Proliferator-Activated Receptor gamma (PPARG) Interaktionspartner

  1. siRNA targeting PPARgamma gene can inhibit adipogenic differentiation of BMSCs and prevent steroid-induced osteonecrosis in rabbit.

  2. vitamin E supplementation affords protection by decreasing MMP-1 (zeige MMP1 Proteine) and increasing PPARg, GSTa (zeige GSTa2 Proteine), and ABCA1 (zeige ABCA1 Proteine) levels in aortae of rabbits fed a cholesterol-rich diet

  3. Telmisartan improves microvascular dysfunction during myocardial ischemia/reperfusion injury via the PPARgamma pathway.

  4. PPARgamma plays a luteotropic role in pseudopregnant rabbits, through PTGS2 (zeige PTGS2 Proteine) down-regulation and 3beta-HSD (zeige HAL Proteine) up-regulation, with a consequent PGF2alpha decrease and progesterone increase.

  5. In an animal model of atherosclerosis, the expression of PPAR-gamma is upregulated following atorvastatin administration.

  6. Tongxinluo can inhibit the expression of MMP-3 (zeige MMP3 Proteine) and 9 and increase the expression of PPARgamma in atherosclerotic rabbits.

  7. Niacin Reduces serum level and adipose mRNA expression of leptin (zeige LEP Proteine) and up-regulates PPARgamma and CD36 (zeige CD36 Proteine) mRNA expression in hypercholesterolemic rabbits.

  8. Antidiabetic drug pioglitazone protects the heart via activation of PPAR-gamma receptors, PI3-kinase (zeige PIK3CA Proteine), Akt (zeige AKT1 Proteine), and eNOS (zeige NOS3 Proteine) pathway in a rabbit model of myocardial infarction.

PPARG Protein Überblick

Protein Überblick

This gene encodes a member of the peroxisome proliferator-activated receptor (PPAR) subfamily of nuclear receptors. PPARs form heterodimers with retinoid X receptors (RXRs) and these heterodimers regulate transcription of various genes. Three subtypes of PPARs are known: PPAR-alpha, PPAR-delta, and PPAR-gamma. The protein encoded by this gene is PPAR-gamma and is a regulator of adipocyte differentiation. Additionally, PPAR-gamma has been implicated in the pathology of numerous diseases including obesity, diabetes, atherosclerosis and cancer. Alternatively spliced transcript variants that encode different isoforms have been described.

Alternative names and synonyms associated with PPARG

  • peroxisome proliferator-activated receptor gamma (PPARG)
  • peroxisome proliferator activated receptor gamma (Pparg)
  • peroxisome proliferator-activated receptor gamma (Pparg)
  • peroxisome proliferator-activated receptor gamma (pparg)
  • PPAR gamma 3 (LOC100008892)
  • CIMT1 Protein
  • GLM1 Protein
  • NR1C3 Protein
  • PPAR-GAMMA Protein
  • PPAR-gamma2 Protein
  • PPARG Protein
  • PPARG1 Protein
  • PPARG2 Protein
  • PPAR gamma Protein
  • PPARGAMMA Protein
  • PPARgamma2 Protein
  • xPPAR-gamma Protein

Bezeichner auf Proteinebene für PPARG

peroxisome proliferator activated receptor gamma , peroxisome proliferative activated receptor gamma , peroxisome proliferator-activated receptor gamma , peroxisome proliferator activator receptor gamma , nuclear receptor subfamily 1 group C member 3 , peroxisome proliferator activated receptor gamma 2 , peroxisome proliferator activated receptor gamma 4 , Nuclear receptor subfamily 1 group C member 3 , PPAR gamma , PPAR-gamma , peroxisome proliferator-activated nuclear receptor gamma variant 1 , peroxisome proliferator-activated receptor gamma 1 , peroxisome proliferator activator receptor, gamma , PPAR gamma 2 , xPPAR gamma , peroxisome proliferative activated receptor, gamma , peroxisome proliferator-activated receptor gamma 2 , peroxisome proliferator-activated receptor gamma 1-a , peroxisome proliferator-activated receptor gamma 1-b , PPAR gamma 1 , peroxisome proliferator activated receptor gamma-1 , peroxisome proliferator-activated receptor-gamma

GENE ID SPEZIES
443513 Ovis aries
460178 Pan troglodytes
100049014 Felis catus
100581046 Nomascus leucogenys
19016 Mus musculus
100689245 Cricetulus griseus
5468 Homo sapiens
25664 Rattus norvegicus
397769 Xenopus laevis
373928 Gallus gallus
403606 Canis lupus familiaris
397671 Sus scrofa
281993 Bos taurus
100729138 Cavia porcellus
574190 Macaca mulatta
100008892 Oryctolagus cuniculus
Ausgewählte Anbieter für PPARG Proteine (PPARG)
Haben Sie etwas anderes gesucht?