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PPARG Proteine (PPARG)

Bezeichnung:
Peroxisome Proliferator-Activated Receptor gamma Proteine (PPARG)
Auf www.antikoerper-online.de finden Sie aktuell 45 Peroxisome Proliferator-Activated Receptor gamma (PPARG) Proteine von 14 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen PPARG Antikörper (304) und PPARG Kits (70) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 436 PPARG Produkte verfügbar.
Synonyme:
CIMT1, GLM1, NR1C3, PPAR-GAMMA, PPAR-gamma2, PPARG, PPARG1, PPARG2, PPAR gamma, PPARGAMMA, PPARgamma2, xPPAR-gamma
alle Proteine anzeigen Gen GeneID UniProt
PPARG 19016 P37238
PPARG 5468 P37231
PPARG 25664 O88275

Weitere Synonyme anzeigen

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Am meisten referenzierte PPARG Proteine

  1. Human PPARG Protein expressed in Escherichia coli (E. coli) - ABIN667157 : Berger, Moller: The mechanisms of action of PPARs. in Annual review of medicine 2002 (PubMed)
    Zeige alle 2 Referenzen für ABIN667157

Weitere Proteine zu PPARG Interaktionspartnern

Mouse (Murine) Peroxisome Proliferator-Activated Receptor gamma (PPARG) Interaktionspartner

  1. Study suggests that D-allose may has therapeutic potential against brain ischemia reperfusion injury through attenuating blood brain barrier disruption and the inflammatory response via PPARgamma-dependent regulation of NF-kappaB (zeige NFKB1 Proteine).

  2. reduced lung levels of PPARgamma and increased levels of microRNA-27a (miR (zeige MLXIP Proteine)-27a), v-ets (zeige ETS1 Proteine) avian erythroblastosis virus E26 oncogene (zeige RAB1A Proteine) homolog 1 (ETS1 (zeige ETS1 Proteine)), endothelin-1 (ET-1 (zeige EDN1 Proteine)), and markers of endothelial dysfunction (platelet/endothelial cell adhesion molecule 1 (zeige PECAM1 Proteine) and E selectin (zeige SELE Proteine)).

  3. Alcohol-induced Toll-like receptor 4 (zeige TLR4 Proteine) endocytosis was reversed by PPARgamma activation.

  4. endogenous KLF4 (zeige KLF4 Proteine) and Krox20 (zeige EGR2 Proteine) are dispensable for adipogenesis in culture and for brown adipose tissue development in mice. In contrast, the master adipogenic transcription factor peroxisome proliferator-activated receptor gamma (PPARgamma) is essential.

  5. These results suggested that HD-14 served as an activator of PPAR-gamma and that the JAK1 (zeige JAK1 Proteine)/STAT1 (zeige STAT1 Proteine) signaling pathway may be involved in the progress of inflammation.

  6. These data demonstrate that genetic deletion of sEH (zeige EPHX2 Proteine) resulted in an altered oxylipin profile, which may have led to an enhanced CRH (zeige CRH Proteine) response.

  7. SHBG (zeige SHBG Proteine) plasma levels regulate hepatic lipogenesis through PPARgamma modulation.

  8. Leukocyte overexpression of intracellular NAMPT (zeige NAMPT Proteine) attenuates atherosclerosis by regulating PPARgamma-dependent monocyte differentiation and function.

  9. Neuronal PPARgamma is required for optimal female fertility but is also involved in the adverse effects of diet-induced obesity by creating leptin (zeige LEP Proteine) resistance potentially through induction of the repressor Socs3 (zeige SOCS3 Proteine).

  10. These results suggest that the major role of PPARgamma is to enhance pathways critical in uptake and reesterification of extrahepatic fatty acids.

Human Peroxisome Proliferator-Activated Receptor gamma (PPARG) Interaktionspartner

  1. reduced lung levels of PPARgamma and increased levels of microRNA-27a (miR (zeige MLXIP Proteine)-27a), v-ets (zeige ETS1 Proteine) avian erythroblastosis virus E26 oncogene (zeige RAB1A Proteine) homolog 1 (ETS1 (zeige ETS1 Proteine)), endothelin-1 (ET-1 (zeige EDN1 Proteine)), and markers of endothelial dysfunction (platelet/endothelial cell adhesion molecule 1 (zeige PECAM1 Proteine) and E selectin (zeige SELE Proteine)).

  2. Alcohol-induced Toll-like receptor 4 (zeige TLR4 Proteine) endocytosis was reversed by PPARgamma activation.

  3. SHBG (zeige SHBG Proteine) plasma levels regulate hepatic lipogenesis through PPARgamma modulation.

  4. Caspase-1 (zeige CASP1 Proteine)-mediated downregulation of PPARgamma was important in the late stage of monocyte-macrophage differentiation; however, PPARgamma protein levels had little effect on the early stage differentiation.

  5. Taken together, these results indicate that ATRA-enhanced expression of DOK1 (zeige DOK1 Proteine) activates PPARgamma leading to inhibition of cell proliferation and enhancement of cell apoptosis in MCF-7 cell.

  6. The study results were suggestive of a positive association between Gly972Arg of IRS1 (zeige IRS1 Proteine) and PCOS in the south Indian population, while INS (zeige INS Proteine), IRS2 (zeige IRS2 Proteine), PPAR-G (zeige ARF6 Proteine) and CAPN10 (zeige CAPN10 Proteine) failed to show any association with PCOS in our studied population.

  7. Human lung fibroblasts activated with proinflammatory IL-1beta (zeige IL1B Proteine) or cigarette smoke extract produce functional PPARgamma ligands; this phenomenon is temporally regulated, COX-2- and lipocalin (zeige APOD Proteine)-type PGD (zeige PGD Proteine) synthase-dependent.

  8. selected 9 nsSNPs variants of PPARgamma ligand binding domain, V290M (zeige PPOX Proteine), R357A, R397C, F360L, P467L, Q286P, R288H, E324K and E460K; investigated effects of a single amino acid change on thermodynamic stability, spectral properties, and molecular dynamics; nsSNPs PPARgamma variants show alteration of dynamics and tertiary contacts that impair the correct reciprocal positioning of helices 3 and 12, important for PPARgamma f...

  9. TGF-beta (zeige TGFB1 Proteine)-treated fibroblasts contained SMAD (zeige SMAD1 Proteine) complexes that activated a SMAD (zeige SMAD1 Proteine) target gene in addition to those repressing PPARG transcription, the first finding of such dual activity within the same cell. These findings describe in detail novel mechanisms by which TGF-beta (zeige TGFB1 Proteine) represses PPARG transcription, thereby facilitating its own pro-fibrotic activity

  10. PPARg-induced miR (zeige MLXIP Proteine)-124 inhibits the production of pro-inflammatory cytokines in severe sepsis.

Pig (Porcine) Peroxisome Proliferator-Activated Receptor gamma (PPARG) Interaktionspartner

  1. The regulatory role of microRNA miR (zeige MYLIP Proteine)-27b-3p on peroxisome proliferator-activated receptor-gamma (PPARgamma) was confirmed by their inversed expression patterns in oocytes: [miR (zeige MYLIP Proteine)-27b-3p]

  2. an Enhancer box and a binding site for a cooperative co-activator of MyoD (zeige MYOD1 Proteine) are present in the promoter region of porcine PPARgamma.

  3. The data suggest that there is local cooperation between resistin (zeige RETN Proteine) and PPARgamma expression in the porcine ovary. Resistin (zeige RETN Proteine) significantly increased the expression of PPARgamma, whereas PPARgamma decreased resistin (zeige RETN Proteine) expression; thus, PPARgamma is a new key regulator of resistin (zeige RETN Proteine) expression and function.

  4. Therefore, this study demonstrated that the different regulatory adipogenic roles of MSTN (zeige MSTN Proteine) in ADSCs and MSCs act by differentially regulating PPARgamma and MyoD (zeige MYOD1 Proteine) expression.

  5. PGRN (zeige GRN Proteine) inhibits adipogenesis in porcine preadipocytes partially through ERK (zeige MAPK1 Proteine) activation mediated PPARgamma phosphorylation.

  6. Resveratrol activated sirtuin 1 (Sirt1 (zeige SIRT1 Proteine)) gene expression and increased adipose triglyceride lipase (ATGL (zeige PNPLA2 Proteine)) gene expression and glycerol release. Furthermore, this study found the opposite Sirt1 (zeige SIRT1 Proteine) regulation pattern for PPARgamma to that of ATGL (zeige PNPLA2 Proteine) in adipocytes.

  7. The results indicate that the endometrial expression of PPARgamma genes fluctuates during the estrous cycle and pregnancy.

  8. Increasing dietary DE linearly enhanced the expression of PPARgamma in adipose tissues but not skeletal muscle of Rongchang piglets.

  9. These results suggest that trans-10, cis (zeige CISH Proteine)-12-conjugated linoleic acid can modulate TNF-alpha (zeige TNF Proteine) production and NF-kappa B (zeige NFKB1 Proteine) expression by a PPARgamma-dependent pathway in porcine peripheral blood mononuclear cells.

  10. The results indicated that PPARgamma gene was significantly associated with litter size in pigs.

Cow (Bovine) Peroxisome Proliferator-Activated Receptor gamma (PPARG) Interaktionspartner

  1. PPARgamma is a positive regulator of milk fat synthesis in dairy cow mammary epithelial cells.

  2. An Asp7Gly substitution in PPARG is associated with adiposity.

  3. upregulation of PPARgamma was observed in the backfat tissue of Lilu cattle with increasing age

  4. Co-culture of adipocytes and myoblasts elicited an increase in C/EBPbeta (zeige CEBPB Proteine) and PPAR-gamma gene expression in differentiated myoblasts and an increase in GPR43 (zeige FFAR2 Proteine) gene expression in adipocytes.

  5. A potential association of an single nucleotide polymorphism (72472 GT in exon7) of the bovine PPAR-gamma gene with carcass and meat quality traits, was evaluated.

  6. study demonstrates the co-expression of DLX3 (zeige DLX3 Proteine), PPARG and SP1 (zeige SP1 Proteine) in trophoblast binucleated cell(BNC)nuclei; this suggests a possible role of these transcription factors through BNC specific genes at the time of pre-placental differentiation

  7. Single nucleotide polymorphisms in coding region of the PPARgamma gene, were examined.

  8. oxidative stress attenuates PPAR gamma expression and activity in vascular endothelial cells

  9. The effects of dietary fat components on the expression of PPAR-gamma AND PPAR-gamma coactivator 1 in cultured bovine preadipocytes are reported.

  10. Intramammary infection elicited a strong transcriptomic response, leading to potent activation of pro-inflammatory pathways that were associated with a marked inhibition of lipid synthesis, stress-activated kinase signaling cascades, and PPAR (zeige PPARA Proteine) signaling.

Rhesus Monkey Peroxisome Proliferator-Activated Receptor gamma (PPARG) Interaktionspartner

  1. study found PPAR-gamma expression was prominent in the subthalamic nucleus, oculomotor nucleus, ventral tegmental nucleus, and to a lesser extent, in the putamen; 3 or 12 months after MPTP (zeige PTPN2 Proteine), only the lesioned putamen had increased PPAR-gamma

  2. Aleglitazar, a dual PPARalpha (zeige PPARA Proteine)/gamma agonist, has beneficial effects on both lipid and glucose parameters in a primate model of the metabolic syndrome.

Rabbit Peroxisome Proliferator-Activated Receptor gamma (PPARG) Interaktionspartner

  1. siRNA targeting PPARgamma gene can inhibit adipogenic differentiation of BMSCs and prevent steroid-induced osteonecrosis in rabbit.

  2. vitamin E supplementation affords protection by decreasing MMP-1 (zeige MMP1 Proteine) and increasing PPARg, GSTa (zeige GSTa2 Proteine), and ABCA1 (zeige ABCA1 Proteine) levels in aortae of rabbits fed a cholesterol-rich diet

  3. Telmisartan improves microvascular dysfunction during myocardial ischemia/reperfusion injury via the PPARgamma pathway.

  4. PPARgamma plays a luteotropic role in pseudopregnant rabbits, through PTGS2 (zeige PTGS2 Proteine) down-regulation and 3beta-HSD (zeige HAL Proteine) up-regulation, with a consequent PGF2alpha decrease and progesterone increase.

  5. In an animal model of atherosclerosis, the expression of PPAR-gamma is upregulated following atorvastatin administration.

  6. Tongxinluo can inhibit the expression of MMP-3 (zeige MMP3 Proteine) and 9 and increase the expression of PPARgamma in atherosclerotic rabbits.

  7. Niacin Reduces serum level and adipose mRNA expression of leptin (zeige LEP Proteine) and up-regulates PPARgamma and CD36 (zeige CD36 Proteine) mRNA expression in hypercholesterolemic rabbits.

  8. Antidiabetic drug pioglitazone protects the heart via activation of PPAR-gamma receptors, PI3-kinase (zeige PIK3CA Proteine), Akt (zeige AKT1 Proteine), and eNOS (zeige NOS3 Proteine) pathway in a rabbit model of myocardial infarction.

PPARG Protein Überblick

Protein Überblick

This gene encodes a member of the peroxisome proliferator-activated receptor (PPAR) subfamily of nuclear receptors. PPARs form heterodimers with retinoid X receptors (RXRs) and these heterodimers regulate transcription of various genes. Three subtypes of PPARs are known: PPAR-alpha, PPAR-delta, and PPAR-gamma. The protein encoded by this gene is PPAR-gamma and is a regulator of adipocyte differentiation. Additionally, PPAR-gamma has been implicated in the pathology of numerous diseases including obesity, diabetes, atherosclerosis and cancer. Alternatively spliced transcript variants that encode different isoforms have been described.

Alternative names and synonyms associated with PPARG

  • peroxisome proliferator-activated receptor gamma (PPARG)
  • peroxisome proliferator activated receptor gamma (Pparg)
  • peroxisome proliferator-activated receptor gamma (Pparg)
  • peroxisome proliferator-activated receptor gamma (pparg)
  • PPAR gamma 3 (LOC100008892)
  • CIMT1 Protein
  • GLM1 Protein
  • NR1C3 Protein
  • PPAR-GAMMA Protein
  • PPAR-gamma2 Protein
  • PPARG Protein
  • PPARG1 Protein
  • PPARG2 Protein
  • PPAR gamma Protein
  • PPARGAMMA Protein
  • PPARgamma2 Protein
  • xPPAR-gamma Protein

Bezeichner auf Proteinebene für PPARG

peroxisome proliferator activated receptor gamma , peroxisome proliferative activated receptor gamma , peroxisome proliferator-activated receptor gamma , peroxisome proliferator activator receptor gamma , nuclear receptor subfamily 1 group C member 3 , peroxisome proliferator activated receptor gamma 2 , peroxisome proliferator activated receptor gamma 4 , Nuclear receptor subfamily 1 group C member 3 , PPAR gamma , PPAR-gamma , peroxisome proliferator-activated nuclear receptor gamma variant 1 , peroxisome proliferator-activated receptor gamma 1 , peroxisome proliferator activator receptor, gamma , PPAR gamma 2 , xPPAR gamma , peroxisome proliferative activated receptor, gamma , peroxisome proliferator-activated receptor gamma 2 , peroxisome proliferator-activated receptor gamma 1-a , peroxisome proliferator-activated receptor gamma 1-b , PPAR gamma 1 , peroxisome proliferator activated receptor gamma-1 , peroxisome proliferator-activated receptor-gamma

GENE ID SPEZIES
443513 Ovis aries
460178 Pan troglodytes
100049014 Felis catus
100581046 Nomascus leucogenys
19016 Mus musculus
100689245 Cricetulus griseus
5468 Homo sapiens
25664 Rattus norvegicus
397769 Xenopus laevis
373928 Gallus gallus
403606 Canis lupus familiaris
397671 Sus scrofa
281993 Bos taurus
100729138 Cavia porcellus
574190 Macaca mulatta
100008892 Oryctolagus cuniculus
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