anti-MAP3K2 (MAP3K2) Antikörper

Bezeichnung:
anti-Mitogen-Activated Protein Kinase Kinase Kinase 2 Antikörper (MAP3K2)
Auf www.antikoerper-online.de finden Sie aktuell 55 Mitogen-Activated Protein Kinase Kinase Kinase 2 (MAP3K2) Antikörper von 12 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen MAP3K2 Proteine (7) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 68 MAP3K2 Produkte verfügbar.
Synonyme:
9630061B06Rik, AI585793, MEKK2, Mekk2b
Alle Antikörper anzeigen Gen GeneID UniProt
MAP3K2 171492  
MAP3K2 10746 Q9Y2U5
MAP3K2 26405  

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Meistgesuchte Reaktivitäten zu anti-MAP3K2 (MAP3K2) Antikörper

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anti-Rat (Rattus) MAP3K2 Antikörper:

anti-Human MAP3K2 Antikörper:

anti-Mouse (Murine) MAP3K2 Antikörper:

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Am meisten referenzierte anti-MAP3K2 Antikörper

  1. Human Monoclonal MAP3K2 Primary Antibody für ICC, ELISA - ABIN969272 : Kurada, Li, Mulherkar, Subramanian, Prasad, Prabhakar: MADD, a splice variant of IG20, is indispensable for MAPK activation and protection against apoptosis upon tumor necrosis factor-alpha treatment. in The Journal of biological chemistry 2009 (PubMed)
    Zeige alle 2 Referenzen für 969272

  2. Human Monoclonal MAP3K2 Primary Antibody für EIA, IF - ABIN1108129 : Spathelf, Rautenbach: Anti-listerial activity and structure-activity relationships of the six major tyrocidines, cyclic decapeptides from Bacillus aneurinolyticus. in Bioorganic & medicinal chemistry 2009 (PubMed)
    Zeige alle 2 Referenzen für 1108129

  3. Cow (Bovine) Polyclonal MAP3K2 Primary Antibody für WB - ABIN2783679 : Wissing, Jänsch, Nimtz, Dieterich, Hornberger, Kéri, Wehland, Daub: Proteomics analysis of protein kinases by target class-selective prefractionation and tandem mass spectrometry. in Molecular & cellular proteomics : MCP 2007 (PubMed)

Weitere Antikörper gegen MAP3K2 Interaktionspartner

Human Mitogen-Activated Protein Kinase Kinase Kinase 2 (MAP3K2) Interaktionspartner

  1. miR (zeige MLXIP Antikörper)-34c-3p may regulate triple-negative breast cancer progression by directly targeting the 3'-untranslated region of mitogen-activated protein kinase kinase kinase 2 (MAP3K2).

  2. Study found miR (zeige MLXIP Antikörper)-186 expression significantly decreased in lung cancer tissues and cells and MAP3K2 expression increased in the same cancer tissues. Also, results confirmed that MAP3K2 is a target gene of miR (zeige MLXIP Antikörper)-186 and both expression correlated with prognosis.

  3. SMYD3 (zeige SMYD3 Antikörper)-mediated methylation of MAP3K2 increases mutant K-Ras (zeige HRAS Antikörper)-induced activation of ERK1/2 (zeige MAPK1/3 Antikörper). (Review)

  4. Restoration of miR17/20a in solid tumor cells enhances the natural killer cell antitumor activity by targeting Mekk2

  5. HBXIP (zeige HBXIP Antikörper) activated ERK1/2 (zeige MAPK1/3 Antikörper) through up-regulating MEKK2.

  6. MEKK2 has a novel function as a regulator of ubiquitylation-dependent paxillin (zeige PXN Antikörper) redistribution in breast tumour cells.

  7. EBV microRNA BART (zeige BSND Antikörper) 18-5p targets MAP3K2 to facilitate persistence in vivo by inhibiting viral replication in B cells.

  8. Inhibitors of apoptosis proteins regulate myogenic differentiation by directly suppressing MEKK2/3-MEK5 (zeige MAP2K5 Antikörper)-ERK5 (zeige MAPK7 Antikörper) signaling.

  9. methylation of MAP3K2 by SMYD3 increases MAP kinase signalling and promotes the formation of Ras-driven carcinomas

  10. results strongly support a role for MEKK2 as a regulator of signaling that modulates breast tumor cell spread area and migration through control of focal adhesion stability

Mouse (Murine) Mitogen-Activated Protein Kinase Kinase Kinase 2 (MAP3K2) Interaktionspartner

  1. FGF2 (zeige FGF2 Antikörper)/MEKK2 pathway mediates an alternative nonclassical pathway for beta-catenin (zeige CTNNB1 Antikörper) activation, and this pathway is a key regulator of bone formation by osteoblasts

  2. Stk38 (zeige STK38 Antikörper) protein kinase (zeige CDK7 Antikörper) has a role in inhibiting TLR9 (zeige TLR9 Antikörper)-activated inflammatory responses by promoting MEKK2 ubiquitination in macrophages

  3. methylation of MAP3K2 by SMYD3 increases MAP kinase signalling and promotes the formation of Ras-driven carcinomas

  4. MEKK2 is regulated through a phosphorylation-dependent association with 14-3-3 (zeige YWHAQ Antikörper), a group of adapters that modulate dimerization and association between proteins

  5. MEKK2 signaling contributes to right ventricular hypertrophy and altered myocardial inflammatory gene expression in response to hypoxia-induced pulmonary hypertension.

  6. MEKK2 alone can suppress T-cell TGF-beta (zeige TGFB1 Antikörper) responses. MEKK2 or MEKK3 (zeige MAP3K3 Antikörper) can cause ERK1/2 (zeige MAPK1/3 Antikörper) to phosphorylate SMAD2 (zeige SMAD2 Antikörper)/3 and suppress R-SMAD (zeige SMAD1 Antikörper)-dependent transcription. MEKK2 and MEKK3 (zeige MAP3K3 Antikörper) play overlapping roles in regulating Th-cell differentiation via TGF-beta (zeige TGFB1 Antikörper)

  7. Data show that HDAC4 (zeige HDAC5 Antikörper) binds and promotes the deacetylation and activation of a key MAP3 kinase, MEKK2.

  8. Data from experiments with Mekk2(-/-) mice show that MEKK2 may be required for controlling the strength of T cell receptor/CD3 (zeige CD3E Antikörper) signaling.

  9. PB1 (zeige GPR97 Antikörper) domain mediates the association of MEKK2 and MEKK3 (zeige MAP3K3 Antikörper) with MEK5 (zeige MAP2K5 Antikörper) and that the respective PB1 (zeige GPR97 Antikörper) domains of these kinases are critical for regulation of the ERK5 (zeige MAPK7 Antikörper) pathway.

  10. Rap1 (zeige TERF2IP Antikörper) and MEKK2 are critical upstream signaling molecules mediating BDNF (zeige BDNF Antikörper) stimulation of ERK5 (zeige MAPK7 Antikörper) in central nervous system neurons

MAP3K2 Antigen-Profil

Beschreibung des Gens

The protein encoded by this gene is a member of serine/threonine protein kinase family. This kinase preferentially activates other kinases involved in the MAP kinase signaling pathway. This kinase has been shown to directly phosphorylate and activate Ikappa B kinases, and thus plays a role in NF-kappa B signaling pathway. This kinase has also been found to bind and activate protein kinase C-related kinase 2, which suggests its involvement in a regulated signaling process.

Alternative names and synonyms associated with MAP3K2

  • mitogen activated protein kinase kinase kinase 2 (Map3k2) Antikörper
  • mitogen-activated protein kinase kinase kinase 2 (MAP3K2) Antikörper
  • mitogen-activated protein kinase kinase kinase 2 (Map3k2) Antikörper
  • 9630061B06Rik Antikörper
  • AI585793 Antikörper
  • MEKK2 Antikörper
  • Mekk2b Antikörper

Bezeichner auf Proteinebene für MAP3K2

mitogen-activated protein kinase kinase kinase 2 , MAP/ERK kinase kinase 2 , MAPK/ERK kinase kinase 2 , MEK kinase 2 , MEKK 2 , mitogen activated protein kinase kinase kinase 2 , protein kinase MEKK2b

GENE ID SPEZIES
171492 Rattus norvegicus
10746 Homo sapiens
26405 Mus musculus
612902 Canis lupus familiaris
100050628 Equus caballus
504592 Bos taurus
424225 Gallus gallus
100621234 Sus scrofa
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