anti-Maus ERK2 Antikörper für Flow Cytometry

Recommended ERK2 Antibody (geliefert von: Anmelden zum Anzeigen )

Antigen
Mitogen-Activated Protein Kinase 1 (MAPK1) Antikörper
  • ATMPK1
  • F14N23.9
  • F14N23_9
  • MITOGEN-ACTIVATED PROTEIN KINASE
  • mitogen-activated protein kinase 1
  • ATMPK2
  • MITOGEN-ACTIVATED PROTEIN KINASE HOMOLOG 2
  • T30E16.13
  • T30E16_13
  • mitogen-activated protein kinase homolog 2
  • ERK2
  • zERK2
  • MAPK1
  • ERK
  • ERT1
  • MAPK2
  • P42MAPK
  • PRKM1
  • PRKM2
  • p38
  • p40
  • p41
  • p41mapk
  • 9030612K14Rik
  • AA407128
  • AU018647
  • C78273
  • Erk2
  • Prkm1
  • p42mapk
  • erk
  • erk2
  • ert1
  • mapk
  • mpk1
  • xp42
  • mapk2
  • prkm1
  • prkm2
  • Xp42
  • mapk1b
  • mapk1
  • mapk1a
  • mitogen-activated protein kinase 1
  • mitogen-activated protein kinase 2
  • mitogen activated protein kinase 1
  • ATMPK1
  • MPK1
  • MPK2
  • MAPK1
  • mapk1
  • Mapk1
  • PfMAP1
  • PVX_084965
  • Tsp_01601
  • mapk1-b
  • mapk1-a
Reaktivität
Human, Maus
351
147
119
50
31
19
14
11
10
9
8
7
5
5
2
2
2
2
2
1
1
1
Wirt
Maus
167
167
17
8
3
Klonalität
Monoklonal
Konjugat
Dieser ERK2 Antikörper ist unkonjugiert
10
9
8
7
4
4
4
4
3
3
3
3
3
3
3
3
3
3
2
2
2
2
1
Applikation
ELISA, Flow Cytometry (FACS), Immunohistochemistry (IHC), Western Blotting (WB)
324
156
92
82
81
62
50
26
20
10
5
3
3
2
2
1
1
1
1
1
1
1
1
Optionen
Hersteller
Anmelden zum Anzeigen
Hersteller Produkt- Nr.
Anmelden zum Anzeigen
Request

Dieses Produkt umsonst

Schicken Sie uns Ihren Validierungsvorschlag. Ich möchte dieses Produkt validieren

Mehr erfahren

Produktnummer ABIN2869484
468,37 €
Zzgl. Versandkosten 20,00 € und MWSt
Relevance Score ABIN Application Konjugat Host Isotype Epitope Hersteller Clonality References Details
1 ABIN2666104 FACS Rabbit IgG Anmelden zum Anzeigen Polyclonal 1
1 ABIN2470904 FACS IHC ELISA WB Mouse IgG2b Anmelden zum Anzeigen 3F8
1 ABIN1838595 FACS ELISA WB Rabbit Anmelden zum Anzeigen Polyclonal
1 ABIN221449 ICC FACS IF IP ELISA WB Rabbit IgG Tyr182, pThr180 Anmelden zum Anzeigen
1 ABIN220478 FACS IP WB Mouse IgG1 Tyr182, pThr180 Anmelden zum Anzeigen
1 ABIN220470 FACS IHC (p) ELISA WB Rabbit IgG Anmelden zum Anzeigen Polyclonal

anti-ERK2 Antikörper für Flow Cytometry mit den meisten Publikationen

Ähnliche anti-ERK2 Antikörper

Applikation / Reaktivität Maus Human
Chromatin Immunoprecipitation (ChIP) 1 Antikörper 1 Antikörper
Electron Microscopy (EM) 1 Antikörper
ELISA 65 Antikörper
Enzyme Immunoassay (EIA) 4 Antikörper
Flow Cytometry (FACS) 7 Antikörper
Immunocytochemistry (ICC) 26 Antikörper
Immunofluorescence (IF) 37 Antikörper
Immunofluorescence (Cultured Cells) (IF (cc)) 1 Antikörper
Immunofluorescence (fixed cells) (IF/ICC) 1 Antikörper
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 1 Antikörper
Immunohistochemistry (IHC) 43 Antikörper
Immunohistochemistry (Frozen Sections) (IHC (fro)) 19 Antikörper
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 41 Antikörper
Immunoprecipitation (IP) 34 Antikörper
Intracellular Staining (ICS) 3 Antikörper
Proximity Ligation Assay (PLA) 2 Antikörper
Western Blotting (WB) 135 Antikörper
Cellular Assay (CA) 1 Antikörper

General

Antigen Mitogen-Activated Protein Kinase 1 (MAPK1) Antikörper
Reaktivität Human, Maus
(351), (147), (119), (50), (31), (19), (14), (11), (10), (9), (8), (7), (5), (5), (2), (2), (2), (2), (2), (1), (1), (1)
Wirt Maus
(167), (167), (17), (8), (3)
Klonalität (Klon)
Monoklonal   ( )
Konjugat Dieser ERK2 Antikörper ist unkonjugiert
(10), (9), (8), (7), (4), (4), (4), (4), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (2), (2), (2), (2), (1)
Applikation ELISA, Flow Cytometry (FACS), Immunohistochemistry (IHC), Western Blotting (WB)
(324), (156), (92), (82), (81), (62), (50), (26), (20), (10), (5), (3), (3), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1)
Pubmed 4 Publikationen vorhanden
Hersteller Anmelden zum Anzeigen

Produktdetails anti-ERK2 Antikörper

Target Details ERK2 Anwendungsinformationen Handhabung ProductDetails: References for anti-ERK2 antibody (ABIN2869484) Bilder
Verwendungszweck Purified Mouse Monoclonal Antibody
Produktmerkmale Synonyms: Mitogen-activated protein kinase 1, MAP kinase 1, MAPK 1, 2.7.11.24, ERT1, Extracellular signal-regulated kinase 2, ERK-2, MAP kinase isoform p42, p42-MAPK, Mitogen-activated protein kinase 2, MAP kinase 2, MAPK 2, MAPK1, ERK2, PRKM1, PRKM2
Immunogen Purified recombinant fragment of human MAPK expressed in E. Coli.

Antigen Type: Recombinant Protein
Klon 3F8
Isotyp IgG2b

Target Details ERK2

Produktdetails anti-ERK2 Antikörper Anwendungsinformationen Handhabung ProductDetails: References for anti-ERK2 antibody (ABIN2869484) Bilder zurück nach oben
Antigen
Andere Bezeichnung MAPK1 (MAPK1 Antibody Abstract)
Hintergrund Mitogen-activated protein kinases (MAPKs) are a widely conserved family of serine/threonine protein kinases involved in many cellular programs such as cell proliferation, differentiation, motility, and death. The p44/42 MAPK (Erk1/2) signaling pathway can be activated in response to a diverse range of extracellular stimuli including mitogens, growth factors, and cytokines and is an important target in the diagnosis and treatment of cancer. Upon stimulation, a sequential three-part protein kinase cascade is initiated, consisting of a MAP kinase kinase kinase (MAPKKK or MAP3K), a MAP kinase kinase (MAPKK or MAP2K), and a MAP kinase (MAPK). Multiple p44/42 MAP3Ks have been identified, including members of the Raf family as well as Mos and Tpl2/Cot. MEK1 and MEK2 are the primary MAPKKs in this pathway. MEK1 and MEK2 activate p44 and p42 through phosphorylation of activation loop residues Thr202/Tyr204 and Thr185/Tyr187, respectively. Several downstream targets of p44/42 have been identified, including p90RSK and the transcription factor Elk-1. p44/42 are negatively regulated by a family of dual-specificity (Thr/Tyr) MAPK phosphatases, known as DUSPs or MKPs, along with MEK inhibitors such as U0126 and PD98059.
Molekulargewicht 41390 Da
Gen-ID 5594
NCBI Accession NP_620407
UniProt P28482
Pathways MAPK Signalweg, RTK Signalweg, Apoptose, Interferon-gamma Pathway, Fc-epsilon Rezeptor Signalübertragung, Response to Growth Hormone Stimulus, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Hepatitis C, Protein targeting to Nucleus, Toll-Like Receptors Cascades, Monocarboxylic Acid Catabolic Process, Autophagie, G-protein mediated Events, Signaling Events mediated by VEGFR1 and VEGFR2, Signaling of Hepatocyte Growth Factor Receptor, VEGFR1 Specific Signals

Anwendungsinformationen

Produktdetails anti-ERK2 Antikörper Target Details ERK2 Handhabung ProductDetails: References for anti-ERK2 antibody (ABIN2869484) Bilder zurück nach oben
Applikationshinweise The suggested dilution is: Western Bloting: = 1:500 - 2000. Flow cytometry: = 1:200 - 400.
Beschränkungen Nur für Forschungszwecke einsetzbar

Handhabung

Produktdetails anti-ERK2 Antikörper Target Details ERK2 Anwendungsinformationen ProductDetails: References for anti-ERK2 antibody (ABIN2869484) Bilder zurück nach oben
Format Liquid
Buffer Ascitic fluid containing 0.03 % sodium azide.
Konservierungsmittel Sodium azide
Vorsichtsmaßnahmen This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung 4 °C/-20 °C
Informationen zur Lagerung Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Haltbarkeit 6 months

ProductDetails: References for anti-ERK2 antibody (ABIN2869484)

Produktdetails anti-ERK2 Antikörper Target Details ERK2 Anwendungsinformationen Handhabung Bilder zurück nach oben
Allgemeine Veröffentlichungen

Lønne, Masoumi, Lennartsson, Larsson: "Protein kinase Cdelta supports survival of MDA-MB-231 breast cancer cells by suppressing the ERK1/2 pathway." in: The Journal of biological chemistry, Vol. 284, Issue 48, pp. 33456-65, 2009

Tabakoff, Saba, Printz, Flodman, Hodgkinson, Goldman, Koob, Richardson, Kechris, Bell, Hübner, Heinig, Pravenec, Mangion, Legault, Dongier, Conigrave, Whitfield, Saunders, Grant, Hoffman,: "Genetical genomic determinants of alcohol consumption in rats and humans." in: BMC biology, Vol. 7, pp. 70, 2009

Schiemann, Graves, Baumann, Morella, Gearing, Nielsen, Krebs, Nathanson: "Phosphorylation of the human leukemia inhibitory factor (LIF) receptor by mitogen-activated protein kinase and the regulation of LIF receptor function by heterologous receptor activation." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 92, Issue 12, pp. 5361-5, 1995

Gonzalez, Raden, Rigby, Davis: "Heterogeneous expression of four MAP kinase isoforms in human tissues." in: FEBS letters, Vol. 304, Issue 2-3, pp. 170-8, 1992