anti-Huhn ERK2 Antikörper für Immunoprecipitation

Recommended ERK2 Antibody (geliefert von: Anmelden zum Anzeigen )

Antigen
Mitogen-Activated Protein Kinase 1 (MAPK1) Antikörper
  • ATMPK1
  • F14N23.9
  • F14N23_9
  • MITOGEN-ACTIVATED PROTEIN KINASE
  • mitogen-activated protein kinase 1
  • ATMPK2
  • MITOGEN-ACTIVATED PROTEIN KINASE HOMOLOG 2
  • T30E16.13
  • T30E16_13
  • mitogen-activated protein kinase homolog 2
  • ERK2
  • zERK2
  • MAPK1
  • ERK
  • ERT1
  • MAPK2
  • P42MAPK
  • PRKM1
  • PRKM2
  • p38
  • p40
  • p41
  • p41mapk
  • 9030612K14Rik
  • AA407128
  • AU018647
  • C78273
  • Erk2
  • Prkm1
  • p42mapk
  • erk
  • erk2
  • ert1
  • mapk
  • mpk1
  • xp42
  • mapk2
  • prkm1
  • prkm2
  • Xp42
  • mapk1b
  • mapk1
  • mapk1a
  • mitogen-activated protein kinase 1
  • mitogen-activated protein kinase 2
  • mitogen activated protein kinase 1
  • ATMPK1
  • MPK1
  • MPK2
  • MAPK1
  • mapk1
  • Mapk1
  • PfMAP1
  • PVX_084965
  • Tsp_01601
  • mapk1-b
  • mapk1-a
Epitop
AA 219-358
61
21
16
11
9
9
8
8
5
5
4
4
4
3
3
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
Reaktivität
Huhn, Hund, Frosch, Human, Maus, Ratte (Rattus)
355
148
119
50
30
19
14
10
10
9
8
7
5
5
2
2
2
2
1
1
1
1
Wirt
Maus
171
167
17
8
3
Klonalität
Monoklonal
Konjugat
Dieser ERK2 Antikörper ist unkonjugiert
10
9
8
7
4
4
4
4
3
3
3
3
3
3
3
3
3
3
2
2
2
2
1
Applikation
Immunofluorescence (IF), Immunoprecipitation (IP), Immunohistochemistry (IHC), Western Blotting (WB)
329
157
96
83
82
62
52
26
22
10
5
3
3
2
2
1
1
1
1
1
1
1
1
Optionen
Hersteller
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Bilder

Produktnummer ABIN967747
Preis und Verfügbarkeit auf Anfrage.
Relevance Score ABIN Application Konjugat Host Isotype Epitope Hersteller Clonality References Details
1 ABIN967748 IF IP IHC WB Mouse IgG2b AA 219-358 Anmelden zum Anzeigen 33-ERK2 5

General

Antigen Mitogen-Activated Protein Kinase 1 (MAPK1) Antikörper
Epitop AA 219-358
(61), (21), (16), (11), (9), (9), (8), (8), (5), (5), (4), (4), (4), (3), (3), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reaktivität Huhn, Hund, Frosch, Human, Maus, Ratte (Rattus)
(355), (148), (119), (50), (30), (19), (14), (10), (10), (9), (8), (7), (5), (5), (2), (2), (2), (2), (1), (1), (1), (1)
Wirt Maus
(171), (167), (17), (8), (3)
Klonalität (Klon)
Monoklonal   ( )
Konjugat Dieser ERK2 Antikörper ist unkonjugiert
(10), (9), (8), (7), (4), (4), (4), (4), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (2), (2), (2), (2), (1)
Applikation Immunofluorescence (IF), Immunoprecipitation (IP), Immunohistochemistry (IHC), Western Blotting (WB)
(329), (157), (96), (83), (82), (62), (52), (26), (22), (10), (5), (3), (3), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1)
Pubmed 5 Publikationen vorhanden
Hersteller Anmelden zum Anzeigen

Produktdetails anti-ERK2 Antikörper

Target Details ERK2 Anwendungsinformationen Handhabung Referenzen für anti-ERK2 Antikörper (ABIN967747) Bilder
Kreuzreaktivität Human, Hund, Maus, Huhn, Frosch
Produktmerkmale 1. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
2. Please refer to us for technical protocols.
3. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.
4. Source of all serum proteins is from USDA inspected abattoirs located in the United States.
Reinigung The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
Immunogen Rat ERK2 aa. 219-358
Klon 33-ERK2
Isotyp IgG2b

Target Details ERK2

Produktdetails anti-ERK2 Antikörper Anwendungsinformationen Handhabung Referenzen für anti-ERK2 Antikörper (ABIN967747) Bilder zurück nach oben
Antigen
Andere Bezeichnung ERK2 (MAPK1 Antibody Abstract)
Hintergrund The family of serine/threonine kinases known as ERKs (extracellular signal regulated kinases) or MAPKs (mitogen-activated protein kinases) are activated after cell stimulation by a wide variety of hormones and growth factors. Cell stimulation induces a signaling cascade that leads to phosphorylation of MEK (MAPK/ERK kinase) which, in turn, activates ERK via tyrosine and threonine phosphorylation. Structural analysis of ERK2 indicates that phosphorylation induces a conformational change that exposes the active site for substrate binding. Myriad proteins represent the downstream effectors for the active ERK and implicate it in the control of cell proliferation and differentiation, as well as regulation of the cytoskeleton. Activation of ERK is normally transient and cells possess dual specificity phosphatases that are responsible for its down-regulation. Furthermore, multiple studies have shown that elevated ERK activity is associated with some cancers. ERK2 is the 42kDa member of the ERK family and is highly homologous to ERK1.
Molekulargewicht 42 kDa
Forschungsgebiet Stem Cells, Signaling, Inflammation
Pathways MAPK Signalweg, RTK Signalweg, Apoptose, Interferon-gamma Pathway, Fc-epsilon Rezeptor Signalübertragung, Response to Growth Hormone Stimulus, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Hepatitis C, Protein targeting to Nucleus, Toll-Like Receptors Cascades, Monocarboxylic Acid Catabolic Process, Autophagie, G-protein mediated Events, Signaling Events mediated by VEGFR1 and VEGFR2, Signaling of Hepatocyte Growth Factor Receptor, VEGFR1 Specific Signals

Anwendungsinformationen

Produktdetails anti-ERK2 Antikörper Target Details ERK2 Handhabung Referenzen für anti-ERK2 Antikörper (ABIN967747) Bilder zurück nach oben
Kommentare

Related Products: ABIN967389

Beschränkungen Nur für Forschungszwecke einsetzbar

Handhabung

Produktdetails anti-ERK2 Antikörper Target Details ERK2 Anwendungsinformationen Referenzen für anti-ERK2 Antikörper (ABIN967747) Bilder zurück nach oben
Format Liquid
Konzentration 250 μg/mL
Buffer Aqueous buffered solution containing BSA, glycerol, and ≤0.09 % sodium azide.
Konservierungsmittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung -20 °C
Informationen zur Lagerung Store undiluted at -20°C.

Referenzen für anti-ERK2 Antikörper (ABIN967747)

Produktdetails anti-ERK2 Antikörper Target Details ERK2 Anwendungsinformationen Handhabung Bilder zurück nach oben
Produkt verwendet in:

Kim, Ju, Oh, Yoon, Song, Kim, Yoo, Bang, Kang, Chun: "ERK-1/2 and p38 kinase oppositely regulate nitric oxide-induced apoptosis of chondrocytes in association with p53, caspase-3, and differentiation status." in: The Journal of biological chemistry, Vol. 277, Issue 2, pp. 1332-9, 2002

Lund-Johansen, Davis, Bishop, de Waal Malefyt: "Flow cytometric analysis of immunoprecipitates: high-throughput analysis of protein phosphorylation and protein-protein interactions." in: Cytometry, Vol. 39, Issue 4, pp. 250-9, 2000

Lehmann, Janda, Pierreux, Rytömaa, Schulze, McMahon, Hill, Beug, Downward: "Raf induces TGFbeta production while blocking its apoptotic but not invasive responses: a mechanism leading to increased malignancy in epithelial cells." in: Genes & development, Vol. 14, Issue 20, pp. 2610-22, 2000

Liu, Tsai, Aird: "Egr-1 gene is induced by the systemic administration of the vascular endothelial growth factor and the epidermal growth factor." in: Blood, Vol. 96, Issue 5, pp. 1772-81, 2000

Visconti, Gadina, Chiariello, Chen, Stancato, Gutkind, OShea: "Importance of the MKK6/p38 pathway for interleukin-12-induced STAT4 serine phosphorylation and transcriptional activity." in: Blood, Vol. 96, Issue 5, pp. 1844-52, 2000

Bilder

Produktdetails anti-ERK2 Antikörper Target Details ERK2 Anwendungsinformationen Handhabung Referenzen für anti-ERK2 Antikörper (ABIN967747) zurück nach oben
Bilder des Herstellers
Western Blotting (WB) image for anti-Mitogen-Activated Protein Kinase 1 (MAPK1) (AA 219-358) antibody (ABIN967747) Western blot analysis of ERK2 on rat pituitary lysate. Lane 1: 1:5000, lane 2: 1:1000...
Immunofluorescence (IF) image for anti-Mitogen-Activated Protein Kinase 1 (MAPK1) (AA 219-358) antibody (ABIN967747) Immunofluorescence staining of MCF7 cells.
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-Mitogen-Activated Protein Kinase 1 (MAPK1) (AA 219-358) antibody (ABIN967747) ERK 2 (clone 33) staining on rat brain. Formalin fixed paraffin section with citrate ...