anti-Schwein Complement Component 5 Antikörper für Enzyme Immunoassay

Recommended Complement Component 5 Antibody (geliefert von: Anmelden zum Anzeigen )

Antigen
Complement Component 5 (C5) Antikörper
  • C5
  • LOC565774
  • C5a
  • C5b
  • CPAMD4
  • Hc
  • RGD1561905
  • He
  • complement component 5
  • similar to complement component C5-1
  • hemolytic complement
  • C5
  • LOC565774
  • Hc
Reaktivität
Rind (Kuh), Ziege, Human, Schwein, Primate
142
22
9
7
1
1
1
1
Wirt
Maus
85
73
11
6
Klonalität
Monoklonal
Konjugat
Unkonjugiert
14
12
6
6
5
4
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Applikation
Enzyme Immunoassay (EIA), Immunohistochemistry (Frozen Sections) (IHC (fro)), Western Blotting (WB)
101
80
28
22
18
15
13
10
10
9
8
7
6
5
4
3
2
2
2
2
1
1
1
1
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Produktnummer ABIN111066
341,00 €
Zzgl. Versandkosten 20,00 € und MWSt

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General

Antigen Complement Component 5 (C5) Antikörper
Reaktivität Rind (Kuh), Ziege, Human, Schwein, Primate
(142), (22), (9), (7), (1), (1), (1), (1)
Wirt Maus
(85), (73), (11), (6)
Klonalität (Klon)
Monoklonal   ( )
Konjugat Unkonjugiert
(14), (12), (6), (6), (5), (4), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Applikation Enzyme Immunoassay (EIA), Immunohistochemistry (Frozen Sections) (IHC (fro)), Western Blotting (WB)
(101), (80), (28), (22), (18), (15), (13), (10), (10), (9), (8), (7), (6), (5), (4), (3), (2), (2), (2), (2), (1), (1), (1), (1)
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Produktdetails

Antigendetails Anwendungsinformationen Handhabung Bilder
Spezifität HCC 5b.1 (neo) allows detection of C5b-9 complexes via activated C5, especially in different forms of glomerulonephritis. Does not react with native C5! Polypeptide Reacting: Mr 200 000 polypeptide of SDS denaturated complement component C5 and C5b of Mr 185 000, after C5b activation, an Mr 60 000 cleavage product also reacts (weakly). Disorders Specifically Detected: Detection of C5b-9 complexes via activated C5, whereas native C5 reacts with antibody HCC 5.1.
Kreuzreaktivität (Details) Species reactivity (tested):Human, Primates, Bovine, Pig, Goat.
Reinigung Affinity Chromatography on Protein A
Immunogen Activated Human Complement Component C5
Klon HCC5b-1 (neo)
Isotyp IgG1

Antigendetails

Produktdetails Anwendungsinformationen Handhabung Bilder zurück nach oben
Antigen
Andere Bezeichnung Complement C5 (C5 Antibody Abstract)
Hintergrund C5 is synthesised in the liver as a single polypeptide chain. Before secretion the molecule is glycosylated and secreted into plasma as a 190 kDa glycoprotein consisting of a disulphide linked alpha-chain (111 kDa) and beta-chain (75 kDa). C5 precursor is first processed by the removal of 4 basic residues, forming two chains, beta and alpha, linked by a disulfide bond. C5 convertase activates C5 by cleaving the alpha chain, releasing C5a anaphylatoxin and generating C5b (beta chain + alpha' chain).Synonyms: CPAMD4, Complement Component 5
Gen-ID 727
NCBI Accession NP_001726
UniProt P01031
Forschungsgebiet Complement Factors
Pathways Komplementsystem, Carbohydrate Homeostasis

Anwendungsinformationen

Produktdetails Antigendetails Handhabung Bilder zurück nach oben
Applikationshinweise ELISA. Immunoblotting (Western blot). Cytological material. Immunohistochemistry on Frozen Sections (1/10). Incubation time: 1h at RT.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Beschränkungen Nur für Forschungszwecke einsetzbar

Handhabung

Produktdetails Antigendetails Anwendungsinformationen Bilder zurück nach oben
Rekonstitution Restore with 1 mL distilled water.
Handhabung This product is photosensitive and should be protected from light
Lagerung 4 °C
Informationen zur Lagerung Prior to and following reconstitution store the antibody undiluted at 2-8 °C. DO NOT FREEZE!