anti-Human Complement Component 5 Antikörper für Intracellular Flow Cytometry

Recommended Complement Component 5 Antibody (geliefert von: Anmelden zum Anzeigen )

Antigen
Complement Component 5 (C5) Antikörper
  • C5
  • LOC565774
  • C5a
  • C5b
  • CPAMD4
  • Hc
  • RGD1561905
  • He
  • complement component 5
  • similar to complement component C5-1
  • hemolytic complement
  • C5
  • LOC565774
  • Hc
Reaktivität
Human
145
22
10
7
2
2
2
1
Wirt
Maus
86
75
11
6
Klonalität
Monoklonal
Konjugat
Biotin
13
12
6
6
5
4
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Applikation
Intracellular Flow Cytometry (ICFC)
105
82
28
22
19
16
13
10
10
9
9
7
6
5
4
3
2
2
2
1
1
1
1
1
Hersteller
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Hersteller Produkt- Nr.
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Bilder

Produktnummer ABIN2660803
Preis und Verfügbarkeit auf Anfrage.
Relevance Score ABIN Application Konjugat Host Isotype Epitope Hersteller Clonality References Details
1 ABIN2660802 ICFC Biotin Mouse IgG1 kappa Anmelden zum Anzeigen G25-2 4

General

Antigen Complement Component 5 (C5) Antikörper
Reaktivität Human
(145), (22), (10), (7), (2), (2), (2), (1)
Wirt Maus
(86), (75), (11), (6)
Klonalität (Klon)
Monoklonal   ( )
Konjugat Biotin
(13), (12), (6), (6), (5), (4), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Applikation Intracellular Flow Cytometry (ICFC)
(105), (82), (28), (22), (19), (16), (13), (10), (10), (9), (9), (7), (6), (5), (4), (3), (2), (2), (2), (1), (1), (1), (1), (1)
Pubmed 4 Publikationen vorhanden
Hersteller Anmelden zum Anzeigen

Produktdetails

Antigendetails Anwendungsinformationen Handhabung Referenzen Bilder
Reinigung The antibody was purified by affinity chromatography, and conjugated with biotin under optimal conditions. The solution is free of unconjugated biotin.
Klon G25-2
Isotyp IgG1 kappa

Antigendetails

Produktdetails Anwendungsinformationen Handhabung Referenzen Bilder zurück nach oben
Antigen
Andere Bezeichnung C5a/C5a/C5 (C5 Antibody Abstract)
Hintergrund C5, complement component 5, is a protein involved in the complement system. It is cleaved into C5a and C5b by the C3/C5 convertase. The smaller fragment C5a is an anaphylatoxin and is released into the fluid surroundings. C5a is a mediator of local inflammatory process. It induces the contraction of smooth muscle, increases vascular permeability and causes histamine release from mast cells and basophilic leukocytes. C5a also stimulates the locomotion of polymorphonuclear leukocytes (chemokinesis) and direct their migration toward sites of inflammation (chemotaxis). C5a contains 74 amino acids and is rapidly metabolised by a serum enzyme, carboxypeptidase B to a 73 amino acid form, C5a des-Arg. The major fragment C5b binds to the membrane initiating the spontaneous assembly of the late complement components, C5-C9, into the membrane attack complex.
Pathways Komplementsystem, Carbohydrate Homeostasis

Anwendungsinformationen

Produktdetails Antigendetails Handhabung Referenzen Bilder zurück nach oben
Applikationshinweise Optimal working dilution should be determined by the investigator.
Beschränkungen Nur für Forschungszwecke einsetzbar

Handhabung

Produktdetails Antigendetails Anwendungsinformationen Referenzen Bilder zurück nach oben
Konzentration 0.5 mg/mL
Buffer Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
Konservierungsmittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung Protect from prolonged exposure to light. Do not freeze.
Lagerung 4 °C
Informationen zur Lagerung The antibody solution should be stored undiluted between 2°C and 8°C.

Referenzen

Produktdetails Antigendetails Anwendungsinformationen Handhabung Bilder zurück nach oben
Allgemeine Veröffentlichungen

Elsner, Oppermann, Czech, Kapp: "C3a activates the respiratory burst in human polymorphonuclear neutrophilic leukocytes via pertussis toxin-sensitive G-proteins." in: Blood, Vol. 83, Issue 11, pp. 3324-31, 1994

Lundwall, Wetsel, Kristensen, Whitehead, Woods, Ogden, Colten, Tack: "Isolation and sequence analysis of a cDNA clone encoding the fifth complement component." in: The Journal of biological chemistry, Vol. 260, Issue 4, pp. 2108-12, 1985

Tack, Morris, Prahl: "Fifth component of human complement: purification from plasma and polypeptide chain structure." in: Biochemistry, Vol. 18, Issue 8, pp. 1490-7, 1979

Fernandez, Hugli: "Primary structural analysis of the polypeptide portion of human C5a anaphylatoxin. Polypeptide sequence determination and assignment of the oligosaccharide attachment site in C5a." in: The Journal of biological chemistry, Vol. 253, Issue 19, pp. 6955-64, 1978

Bilder

Produktdetails Antigendetails Anwendungsinformationen Handhabung Referenzen zurück nach oben
Bilder des Herstellers
ELISA image for anti-Complement Component 5 (C5) antibody (Biotin) (ABIN2660803) anti-Complement Component 5 (C5) antibody (Biotin)