anti-Ratte (Rattus) PTPN11 Antikörper für Enzyme Immunoassay

Recommended PTPN11 Antibody (geliefert von: Anmelden zum Anzeigen )

Antigen
Protein tyrosine Phosphatase, Non-Receptor Type 11 (PTPN11) Antikörper
  • BPTP3
  • CFC
  • NS1
  • PTP-1D
  • PTP2C
  • SH-PTP2
  • SH-PTP3
  • SHP2
  • 2700084A17Rik
  • AW536184
  • PTP1D
  • SAP-2
  • SHP-2
  • Shp2
  • Syp
  • SYP
  • protein tyrosine phosphatase, non-receptor type 11
  • PTPN11
  • Ptpn11
Epitop
C-Term
53
50
30
21
19
17
15
15
15
10
5
3
3
3
3
3
3
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reaktivität
Human, Maus, Ratte (Rattus)
373
230
201
14
13
13
11
11
10
9
7
4
3
3
2
2
2
1
Wirt
Kaninchen
303
58
19
2
1
Klonalität
Polyklonal
Konjugat
Dieser PTPN11 Antikörper ist unkonjugiert
10
9
9
7
6
5
4
4
4
4
4
4
4
4
4
4
4
2
2
1
1
1
1
1
1
1
1
1
1
1
Applikation
Enzyme Immunoassay (EIA), Western Blotting (WB)
291
128
106
85
52
49
36
22
18
6
3
3
3
2
1
1
1
Hersteller
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Hersteller Produkt- Nr.
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Produktnummer ABIN5555215
$ 375.38
Zzgl. Versandkosten $45.00
Relevance Score ABIN Application Konjugat Host Isotype Epitope Hersteller Clonality References Details
1 ABIN5555216 EIA WB Rabbit IgG N-Term Anmelden zum Anzeigen Polyclonal

General

Antigen Protein tyrosine Phosphatase, Non-Receptor Type 11 (PTPN11) Antikörper
Epitop C-Term
(53), (50), (30), (21), (19), (17), (15), (15), (15), (10), (5), (3), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reaktivität Human, Maus, Ratte (Rattus)
(373), (230), (201), (14), (13), (13), (11), (11), (10), (9), (7), (4), (3), (3), (2), (2), (2), (1)
Wirt Kaninchen
(303), (58), (19), (2), (1)
Klonalität
Polyklonal
Konjugat Dieser PTPN11 Antikörper ist unkonjugiert
(10), (9), (9), (7), (6), (5), (4), (4), (4), (4), (4), (4), (4), (4), (4), (4), (4), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Applikation Enzyme Immunoassay (EIA), Western Blotting (WB)
(291), (128), (106), (85), (52), (49), (36), (22), (18), (6), (3), (3), (3), (2), (1), (1), (1)
Hersteller Anmelden zum Anzeigen

Produktdetails anti-PTPN11 Antikörper

Target Details PTPN11 Anwendungsinformationen Handhabung Bilder
Spezifität This antibody detects PTPN11 / SHP-2 at C-term.
Kreuzreaktivität (Details) Species reactivity (tested):Human, mouse, rat
Reinigung Peptide affinity chromatography
Immunogen SHP2 antibody was raised against a 14 amino acid peptide from near the carboxy terminus of human SHP2.
Isotyp IgG

Target Details PTPN11

Produktdetails anti-PTPN11 Antikörper Anwendungsinformationen Handhabung Bilder zurück nach oben
Antigen
Andere Bezeichnung PTPN11 / PTP2C (PTPN11 Antibody Abstract)
Hintergrund Src homology-2 domain containing protein (SHP2) is a member of the protein tyrosine phosphatase (PTP) family, a protein family that contains signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. SHP2 contains two tandem Src homology-2 (SH2) domains, which function as phosphotyrosine binding domains either directly or through scaffolding intermediates such as the insulin-receptor substrate 1 (IRS-1). These SH2 domains mediate the interaction of SHP2 with its substrates, allowing SHP2 to dephosphorylate proteins that inhibit signaling kinases such as ERK1 and AKT. SHP2 is widely expressed in most tissues and plays a regulatory role in various cell signaling events that are important for a diversity of cell functions, such as mitogenic activation, metabolic control, transcription regulation, and cell migration. Recent experiments have shown SHP2 plays a significant role in hepatoprotection and liver regeneration.Synonyms: PTP-1D, PTP-2C, Protein-tyrosine phosphatase 1D, Protein-tyrosine phosphatase 2C, SH-PTP2, SH-PTP3, SHP-2, SHPTP2, Shp2, Tyrosine-protein phosphatase non-receptor type 11
Gen-ID 5781
NCBI Accession NP_002825
UniProt Q06124
Pathways JAK-STAT Signalweg, RTK Signalweg, T-Zell Rezeptor Signalweg, Interferon-gamma Pathway, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Negative Regulation of Hormone Secretion, Carbohydrate Homeostasis, Toll-Like Receptors Cascades, CXCR4-mediated Signaling Events, Signaling Events mediated by VEGFR1 and VEGFR2, Signaling of Hepatocyte Growth Factor Receptor, VEGFR1 Specific Signals

Anwendungsinformationen

Produktdetails anti-PTPN11 Antikörper Target Details PTPN11 Handhabung Bilder zurück nach oben
Applikationshinweise ELISA. Western blot: 0.5 - 1 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Beschränkungen Nur für Forschungszwecke einsetzbar

Handhabung

Produktdetails anti-PTPN11 Antikörper Target Details PTPN11 Anwendungsinformationen Bilder zurück nach oben
Buffer PBS containing 0.02 % sodium azide
Konservierungsmittel Sodium azide
Vorsichtsmaßnahmen This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung Avoid repeated freezing and thawing.
Lagerung 4 °C/-20 °C
Informationen zur Lagerung Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.