anti-Human CSF2RA Antikörper für Immunocytochemistry

Recommended CSF2RA Antibody (geliefert von: Anmelden zum Anzeigen )

Antigen
Colony Stimulating Factor 2 Receptor, Alpha, Low-Affinity (Granulocyte-Macrophage) (CSF2RA) Antikörper
  • CD116
  • CDw116
  • CSF2R
  • CSF2RAX
  • CSF2RAY
  • CSF2RX
  • CSF2RY
  • GM-CSF-R-alpha
  • GMCSFR
  • GMR
  • SMDP4
  • Csfgmra
  • GM-CSF-Ra
  • GM-CSFR
  • colony stimulating factor 2 receptor, alpha
  • colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage)
  • CSF2RA
  • Csf2ra
Reaktivität
Human
174
45
8
Wirt
Maus
96
83
27
4
Klonalität
Monoklonal
Konjugat
Dieser CSF2RA Antikörper ist konjugiert mit FITC
17
12
9
8
8
7
7
6
6
6
5
5
4
2
2
2
2
2
2
2
2
2
1
Applikation
Functional Studies (Func), Immunocytochemistry (ICC), Flow Cytometry (FACS), Immunofluorescence (IF), Intracellular Flow Cytometry (ICFC), Immunoprecipitation (IP), Immunohistochemistry (IHC), Western Blotting (WB)
123
109
50
25
14
9
9
4
4
3
3
2
2
2
2
1
1
1
Hersteller
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Hersteller Produkt- Nr.
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Bilder

Produktnummer ABIN2661473
Preis und Verfügbarkeit auf Anfrage.
Relevance Score ABIN Application Konjugat Host Isotype Epitope Hersteller Clonality References Details
1 ABIN1858512 ICC IHC IP WB Rabbit IgG AA 204-360 Anmelden zum Anzeigen Polyclonal
1 ABIN1867408 ICC IHC IP WB Rabbit IgG AA 28-112 Anmelden zum Anzeigen Polyclonal

General

Antigen Colony Stimulating Factor 2 Receptor, Alpha, Low-Affinity (Granulocyte-Macrophage) (CSF2RA) Antikörper
Reaktivität Human
(174), (45), (8)
Wirt Maus
(96), (83), (27), (4)
Klonalität (Klon)
Monoklonal   ( )
Konjugat Dieser CSF2RA Antikörper ist konjugiert mit FITC
(17), (12), (9), (8), (8), (7), (7), (6), (6), (6), (5), (5), (4), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1)
Applikation Functional Studies (Func), Immunocytochemistry (ICC), Flow Cytometry (FACS), Immunofluorescence (IF), Intracellular Flow Cytometry (ICFC), Immunoprecipitation (IP), Immunohistochemistry (IHC), Western Blotting (WB)
(123), (109), (50), (25), (14), (9), (9), (4), (4), (3), (3), (2), (2), (2), (2), (1), (1), (1)
Pubmed 5 Publikationen vorhanden
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Produktdetails anti-CSF2RA Antikörper

Target Details CSF2RA Anwendungsinformationen Handhabung Referenzen für anti-CSF2RA Antikörper (ABIN2661473) Bilder
Reinigung The antibody was purified by affinity chromatography, and conjugated with FITC under optimal conditions. The solution is free of unconjugated FITC.
Klon 4H1
Isotyp IgG1 kappa

Target Details CSF2RA

Produktdetails anti-CSF2RA Antikörper Anwendungsinformationen Handhabung Referenzen für anti-CSF2RA Antikörper (ABIN2661473) Bilder zurück nach oben
Antigen
Andere Bezeichnung CD116 (CSF2RA Antibody Abstract)
Hintergrund CD116 is a 70-85 kD α chain of the GM-CSF receptor. It combines with CDw131 β chain to form the high affinity GM-CSF receptor. A soluble form of CD116, which binds GM-CSF with a relatively low affinity, has been identified. In addition, an alternatively spliced form of CD116 with an altered cytoplasmic tail has been described. CD116 is expressed on various myeloid cells including monocytes, macrophages, neutrophils, eosinophils, dendritic cells and their precursors, fibroblasts, and endothelial cells. CD116 is expressed on myeloid leukemias, osteogenic sarcoma cell lines, osteoblast-like cells and breast and lung carcinoma cell lines.
Forschungsgebiet CD Antigens, Surface Receptors of Immune Cells
Pathways JAK-STAT Signalweg

Anwendungsinformationen

Produktdetails anti-CSF2RA Antikörper Target Details CSF2RA Handhabung Referenzen für anti-CSF2RA Antikörper (ABIN2661473) Bilder zurück nach oben
Applikationshinweise Optimal working dilution should be determined by the investigator.
Beschränkungen Nur für Forschungszwecke einsetzbar

Handhabung

Produktdetails anti-CSF2RA Antikörper Target Details CSF2RA Anwendungsinformationen Referenzen für anti-CSF2RA Antikörper (ABIN2661473) Bilder zurück nach oben
Buffer Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and 0.2 % (w/v) BSA .
Konservierungsmittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung Protect from prolonged exposure to light. Do not freeze.
Lagerung 4 °C
Informationen zur Lagerung The antibody solution should be stored undiluted between 2°C and 8°C.

Referenzen für anti-CSF2RA Antikörper (ABIN2661473)

Produktdetails anti-CSF2RA Antikörper Target Details CSF2RA Anwendungsinformationen Handhabung Bilder zurück nach oben
Allgemeine Veröffentlichungen

Lee, Breton, Oliveira, Zhou, Aljoufi, Puhr, Cameron, Sékaly, Nussenzweig, Liu: "Restricted dendritic cell and monocyte progenitors in human cord blood and bone marrow." in: The Journal of experimental medicine, Vol. 212, Issue 3, pp. 385-99, 2015

Guthridge, Barry, Felquer, McClure, Stomski, Ramshaw, Lopez: "The phosphoserine-585-dependent pathway of the GM-CSF/IL-3/IL-5 receptors mediates hematopoietic cell survival through activation of NF-kappaB and induction of bcl-2." in: Blood, Vol. 103, Issue 3, pp. 820-7, 2004

McClure, Stomski, Lopez, Woodcock: "Perverted responses of the human granulocyte-macrophage colony-stimulating factor receptor in mouse cell lines due to cross-species beta-subunit association." in: Blood, Vol. 98, Issue 10, pp. 3165-8, 2001

Stomski, Woodcock, Zacharakis, Bagley, Sun, Lopez et al.: "Identification of a Cys motif in the common beta chain of the interleukin 3, granulocyte-macrophage colony-stimulating factor, and interleukin 5 receptors essential for disulfide-linked receptor ..." in: The Journal of biological chemistry, Vol. 273, Issue 2, pp. 1192-9, 1998

Miyajima, Mui, Ogorochi, Sakamaki: "Receptors for granulocyte-macrophage colony-stimulating factor, interleukin-3, and interleukin-5." in: Blood, Vol. 82, Issue 7, pp. 1960-74, 1993

Bilder

Produktdetails anti-CSF2RA Antikörper Target Details CSF2RA Anwendungsinformationen Handhabung Referenzen für anti-CSF2RA Antikörper (ABIN2661473) zurück nach oben
Bilder des Herstellers
Flow Cytometry (FACS) image for anti-Colony Stimulating Factor 2 Receptor, Alpha, Low-Affinity (Granulocyte-Macrophage) (CSF2RA) antibody (FITC) (ABIN2661473) anti-Colony Stimulating Factor 2 Receptor, Alpha, Low-Affinity (Granulocyte-Macrophage) (CSF2RA) antibody (FITC)