No reaction was observed against anti - Trypsin, anti - Human IgG F (ab'), anti - 2 Human IgG Fc, anti - Human kappa or anti - Human lambda.
Produktmerkmale
Purified Human IgM protein (Fc 5 mu) Source: Human IgM myeloma Alternative Names: Immunoglobulin M protein (Human) (Fc5mu) Physical state: Clear, colorless liquid
Optimal working dilutions should be determined experimentally by the investigator.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Konzentration
Lot specific
Buffer
0.1 M TRIS-HCl, pH 8.0, with 0.1 NaCl, and 0.05 % NaN3.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
Handhabung
Avoid repeated freeze/thaw cycles. Dilute only prior to immediate use.
IgM constant region Isotype Control, IGM Isotype Control
Substanzklasse
Antibody
Hintergrund
IgM is found in normal plasma at a concentration of 1.2 to 4.0 mg/mL. It is the first immunoglobulin produced during the immune response, the first antibody in neonates, and is involved in pathogenesis of autoimmune diseases. A diminished level of IgM is associated with Wiskott-Aldrich syndrome.