Ratte IgG2b,kappa Isotyp-Kontrolle

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Isotyp
Wirt
Ratte
61
55
Klonalität (Klon)
Monoklonal ()
Applikation
Isotype Control (IsoC), Western Blotting (WB)
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Klon RTK4530
Isotyp IgG2b kappa
Fragment Chain kappa
Produktmerkmale The isotype of RTK4530 immunoglobulin is rat IgG2b, κ. This antibody was chosen as an isotype control after screening on a variety of resting, activated, live, and fixed mouse, rat and human tissues.
Reinigung The immunoglobulin was purified by affinity chromatography, and conjugated with PerCP under optimal conditions. The solution is free of unconjugated PerCP and unconjugated immunoglobulin.
Andere Bezeichnung IgG2b kappa
Forschungsgebiet Secondary Antibodies
Applikationshinweise Optimal working dilution should be determined by the investigator.
Beschränkungen Nur für Forschungszwecke einsetzbar
Konzentration 0.2 mg/mL
Buffer Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
Konservierungsmittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung Protect from prolonged exposure to light. Do not freeze.
Lagerung 4 °C
Informationen zur Lagerung The antibody solution should be stored undiluted between 2°C and 8°C.
Allgemeine Veröffentlichungen Schaefer, Montufar-Solis, Vigneswaran, Klein: "ICOS promotes IL-17 synthesis in colonic intraepithelial lymphocytes in IL-10-/- mice." in: Journal of leukocyte biology, Vol. 87, Issue 2, pp. 301-8, 2010 (PubMed).

Yi, Yu, Gao, Wang, Baek, Chen, Kim, Subjeck, Wang: "Pattern recognition scavenger receptor SRA/CD204 down-regulates Toll-like receptor 4 signaling-dependent CD8 T-cell activation." in: Blood, Vol. 113, Issue 23, pp. 5819-28, 2009 (PubMed).

Duan, Avci, Kasper: "Microbial carbohydrate depolymerization by antigen-presenting cells: deamination prior to presentation by the MHCII pathway." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 105, Issue 13, pp. 5183-8, 2008 (PubMed).

Sasaki, Zhao, Pardee, Ueda, Fujita, Sehra, Kaplan, Kane, Okada, Storkus: "Stat6 signaling suppresses VLA-4 expression by CD8+ T cells and limits their ability to infiltrate tumor lesions in vivo." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 181, Issue 1, pp. 104-8, 2008 (PubMed).

Cervantes-Barragan, Züst, Weber, Spiegel, Lang, Akira, Thiel, Ludewig: "Control of coronavirus infection through plasmacytoid dendritic-cell-derived type I interferon." in: Blood, Vol. 109, Issue 3, pp. 1131-7, 2007 (PubMed).

Zeiser, Nguyen, Hou, Beilhack, Zambricki, Buess, Contag, Negrin: "Early CD30 signaling is critical for adoptively transferred CD4+CD25+ regulatory T cells in prevention of acute graft-versus-host disease." in: Blood, Vol. 109, Issue 5, pp. 2225-33, 2007 (PubMed).