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Human IFNGR1 ELISA Kit für Sandwich ELISA - ABIN841846
Razali, Abdul Aziz, Lim, Mat Junit: Investigation into the effects of antioxidant-rich extract of Tamarindus indica leaf on antioxidant enzyme activities, oxidative stress and gene expression profiles in HepG2 cells. in PeerJ 2015
results showed a significant correlation between IFNGR1- T-56CSNP and Nontuberculous mycobacteria infection among studied populations
Data suggest IFNG (zeige IFNG ELISA Kits) plays various roles in dynamics of inflammation in subjects with underlying autoimmunity modeled as "canonical" and "non-canonical" pathways; in canonical pathway, IFNG (zeige IFNG ELISA Kits) dimerizes and binds to IFNGR1 in IFNGR1/IFNGR2 (zeige IFNGR2 ELISA Kits) hetero-multimer; STAT (zeige STAT1 ELISA Kits) transcription factors are involved in non-canonical pathway. (IFNG (zeige IFNG ELISA Kits) = interferon gamma (zeige IFNG ELISA Kits); IFNGR = IFNG (zeige IFNG ELISA Kits) receptor; STAT (zeige STAT1 ELISA Kits) = signal transducers and activators of transcription)
The study did not provide enough powerful evidence to identify a significant association between IFNGR1 -56C/T polymorphism and tuberculosis susceptibility (meta-analysis).
All patients tested were positive for mycobacteria; one was heterozygous for the IFNGR1 exon 5 single-nucleotide-missense substitution
The deletion of IFNGR1 causes complete IFN-gammaR1 deficiency. Despite the deletion ending very close to the IL22RA2 (zeige IL22RA2 ELISA Kits) gene, it does not appear to affect IL22RA2 (zeige IL22RA2 ELISA Kits) transcription.
A significant association of IFN-gammaR1 and P2X7 (zeige P2RX7 ELISA Kits) genes polymorphisms with risk of developing TB in Iranian population.
Mendelian susceptibility to mycobacteria due to a partial dominant mutation of the interferon gamma receptor 1 gene.
Targeted deep sequencing identifies rare loss-of-function variants in IFNGR1 for risk of atopic dermatitis complicated by eczema herpeticum
Statistical analyses revealed that four genetic variants in IFNGR1 were marginally associated with the risk of Tuberculosis (P = 0.02-0.04), while other single nucleotide polymorphisms in IFNGR1 and IFNGR2 (zeige IFNGR2 ELISA Kits) did not exhibit any associations
Uniformly low expression of IFN and IFNGR1 in post Kala-azar dermal leishmaniasis skin biopsies could explain parasite persistence and is consistent with prior demonstration of genetic association with IFNGR1 polymorphisms.
significant upregulation of genes involved in inflammation and tissue remodeling in intestinal tumors of Ifngr1-/-ApcMin/+ mice when compared to those in Ifngr1+/+ApcMin/+ mice
These findings suggest that IFNGR1 signaling plays a pivotal role in placental pathology and subsequent adverse pregnancy outcomes during severe malaria. Our findings may increase our understanding of how disease aggravation occurs during malaria during pregnancy.
Down regulation of macrophage IFNGR1 resists infection by Listeria monocytogenes.
Marginal zone macrophage population loss is dependent on interferon gamma (zeige IFNG ELISA Kits) receptor but independent of T cells or tumor necrosis factor alpha receptor (zeige TNFRSF1A ELISA Kits) 1 signaling pathways.
These results suggest that pulmonary C-fibers affect IFNGR1 expression by inducing IFN-alpha (zeige IFNA ELISA Kits) to regulate IFN-gamma (zeige IFNG ELISA Kits)-mediated airway inflammation and airway hyperresponsiveness.
data define a novel B cell-intrinsic IFN-gammaR signaling pathway specific to Spt (zeige AGXT ELISA Kits)-GC development and autoimmunity.
These data offer direct evidence that tumor cell loss of the IFNGR1 gene, which results in loss of IFN-g (zeige IFNG ELISA Kits) signaling, leads to resistance to anti-CTLA-4 (zeige CTLA4 ELISA Kits) therapy.
These data indicate that both GKO and GRKO mice fail to develop an IFN-gamma (zeige IFNG ELISA Kits)-mediated antiviral response, but differ in regulation of the inflammatory response to infection.
IFN-gamma (zeige IFNG ELISA Kits) Ralpha is a key determinant of CD8 (zeige CD8A ELISA Kits)+ T cell-mediated tumor elimination or tumor escape and relapse in FVB mouse.
Data indicate that prolonged IFNgammaR-/- dendritic cell survival promotes CD4 (zeige CD4 ELISA Kits) T cell expansion.
analysis of mir (zeige MYLIP ELISA Kits)-378 and of the interferon gamma receptor 1 protein at different stages of luteal development showed that mir (zeige MYLIP ELISA Kits)-378 decreased the expression of interferon gamma receptor 1 protein but not the mRNA
SNPs in IFNG (zeige IFNG ELISA Kits), IFNGR1 and R2, IL22 (zeige IL22 ELISA Kits), and IL22RA1 (zeige IL22RA1 ELISA Kits) were analyzed for an association to Estimated breeding values for somatic cell score in Canadian Holstein bulls; no significant associations were found.
The receptor complex for Ifn-gamma2 includes cytokine receptor (zeige LEPR ELISA Kits) family B (Crfb)6 together with Crfb13 and Crfb17.
This gene (IFNGR1) encodes the ligand-binding chain (alpha) of the gamma interferon receptor. Human interferon-gamma receptor is a heterodimer of IFNGR1 and IFNGR2. A genetic variation in IFNGR1 is associated with susceptibility to Helicobacter pylori infection. In addition, defects in IFNGR1 are a cause of mendelian susceptibility to mycobacterial disease, also known as familial disseminated atypical mycobacterial infection.
AVP, type 2
, CD119 antigen
, IFN-gamma receptor 1
, antiviral protein, type 2
, immune interferon receptor 1
, interferon-gamma receptor alpha chain
, INF-g receptor
, interferon-gamma receptor 1
, interferon gamma receptor 1