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Integrin, alpha 4 (Antigen CD49D, alpha 4 Subunit of VLA-4 Receptor) Proteine (ITGA4)

Bezeichnung:
Integrin, alpha 4 (Antigen CD49D, alpha 4 Subunit of VLA-4 Receptor) Proteine (ITGA4)
Auf www.antikoerper-online.de finden Sie aktuell 7 Integrin, alpha 4 (Antigen CD49D, alpha 4 Subunit of VLA-4 Receptor) (ITGA4) Proteine von 3 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen Integrin, alpha 4 (Antigen CD49D, alpha 4 Subunit of VLA-4 Receptor) Antikörper (424) und Integrin, alpha 4 (Antigen CD49D, alpha 4 Subunit of VLA-4 Receptor) Kits (5) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 439 Integrin, alpha 4 (Antigen CD49D, alpha 4 Subunit of VLA-4 Receptor) Produkte verfügbar.
Synonyme:
CD49D, IA4, LOC100219853
alle Proteine anzeigen Gen GeneID UniProt
ITGA4 16401 Q00651
Ratte ITGA4 ITGA4 311144  
ITGA4 3676 P13612

Weitere Synonyme anzeigen

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Weitere Proteine zu Integrin, alpha 4 (Antigen CD49D, alpha 4 Subunit of VLA-4 Receptor) Interaktionspartnern

Mouse (Murine) Integrin, alpha 4 (Antigen CD49D, alpha 4 Subunit of VLA-4 Receptor) (ITGA4) Interaktionspartner

  1. Macrophage tissue factor (zeige F3 Proteine) prothrombotic activity is regulated by integrin-alpha4/arf6 (zeige ARF6 Proteine) trafficking.

  2. this study shows that alpha4beta1 integrin mediates memory CD8 (zeige CD8A Proteine)+ T cells accumulation in salivary glands after infection with lymphocytic choriomeningitis virus

  3. The results uncovered a previously unknown role of integrin a4b7-MAdCAM-1 (zeige MADCAM1 Proteine) interactions as drivers of colitis by directing inflammatory monocytes into the colon.

  4. These results suggest that Tie2 (zeige TEK Proteine) signaling induces alpha4beta1 integrin activation on bone marrow-mast cell progenitor for adhesion to VCAM-1 (zeige VCAM1 Proteine).

  5. ITGA4 expression enhances metastasis in MYCN (zeige MYCN Proteine) low neuroblastoma (zeige ARHGEF16 Proteine).

  6. CD49d-high-expressing Th1 (zeige HAND1 Proteine) memory phenotype CD4 (zeige CD4 Proteine)+ T cells with enhanced B cell helper activity develop early in the peritoneal cavity.

  7. Data suggest that bortezomib mobilizes hematopoietic stem cells (HSPCs) by modulation of the integrin alpha4beta1 (VLA)-4/vascular cell adhesion molecule-1 (VCAM-1 (zeige VCAM1 Proteine)) axis.

  8. Consistent with a role of alpha4beta7 in the generation of intestinal mononuclear phagocytes, bone marrow cells from beta7(-/-) mice poorly reconstituted small intestine retinoic acid (RA)-producing CD11c (zeige ITGAX Proteine)(hi) dendritic cells.

  9. SP/drug efflux functionality of hematopoietic progenitors is controlled by mesenchymal niche through VLA-4/CD44 (zeige CD44 Proteine) axis.

  10. We conclude that integrin alpha4beta1 is necessary for CD4 (zeige CD4 Proteine)(+) T cell-mediated protection against C. trachomatis infection in the genital mucosa.

Human Integrin, alpha 4 (Antigen CD49D, alpha 4 Subunit of VLA-4 Receptor) (ITGA4) Interaktionspartner

  1. Macrophage tissue factor (zeige F3 Proteine) prothrombotic activity is regulated by integrin-alpha4/arf6 (zeige ARF6 Proteine) trafficking.

  2. gut (zeige GUSB Proteine)-homing alpha4beta7 CD4 (zeige CD4 Proteine)(+) T cells and their functional subsets were profoundly depleted during acute HIV-1 infection.

  3. Data show tht Rho kinase (zeige ROCK1 Proteine) (ROCK) activity was increased by inhibiting integrin alpha4 with human umbilical vein endothelial cells (HUVECs) and hypoxia.

  4. These data showed that Mycobacterium tuberculosis ESAT-6 and ESAT-6/CFP (zeige CFP Proteine)-10 fusion proteins could induce adhesion of macrophages to fibronectin (zeige FN1 Proteine) through alpha4beta1 integrin.

  5. Enhanced susceptibility of activated endocervical CD4+ T cells to HIV may be related to increased CCR5 expression by these cell subsets, but did not appear to be due to direct interaction of integrins a4b7 or a4b1 with HIV envelope.

  6. knockdown of PTTG1 (zeige PTTG1 Proteine) increased expression of integrin alpha 4 (ITGA4), ITGA5 (zeige ITGA5 Proteine), and integrin beta 1 (ITGB1 (zeige ITGB1 Proteine)); otherwise, RhoA (zeige RHOA Proteine) expression was significantly decreased

  7. Integrin alpha 2 (zeige ITGA2 Proteine) and alpha 4 Yxxphi motifs interact with the endocytic clathrin adaptor, AP2 complex (zeige AP2B1 Proteine).

  8. ITGA4 expression enhances metastasis in MYCN (zeige MYCN Proteine) low neuroblastoma (zeige ARHGEF16 Proteine).

  9. Data show that a small molecule inhibitor of the MYC (zeige MYC Proteine) transcription factor can be an effective anticancer agent when delivered using a integrin alphavbeta3 (zeige ITGAV Proteine) and VLA-4-targeted nanotherapy approach.

  10. Collectively, these data suggest a role for alpha4beta7 integrin in HIV infection that is influenced by both viral and host factors including the sequence of the HIV gp120 (zeige ITIH4 Proteine) alpha4beta7 binding motif, the cytokine milieu and bacterial vaginosis in the genital tract.

Integrin, alpha 4 (Antigen CD49D, alpha 4 Subunit of VLA-4 Receptor) (ITGA4) Protein Überblick

Protein Überblick

The product of this gene belongs to the integrin alpha chain family of proteins. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This gene encodes an alpha 4 chain. Unlike other integrin alpha chains, alpha 4 neither contains an I-domain, nor undergoes disulfide-linked cleavage. Alpha 4 chain associates with either beta 1 chain or beta 7 chain.

Alternative names and synonyms associated with Integrin, alpha 4 (Antigen CD49D, alpha 4 Subunit of VLA-4 Receptor) (ITGA4)

  • integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor) (LOC100219853)
  • integrin alpha 4 (Itga4)
  • integrin, alpha 4 (Itga4)
  • integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor) (ITGA4)
  • CD49D Protein
  • IA4 Protein
  • LOC100219853 Protein

Bezeichner auf Proteinebene für ITGA4

CD49 antigen-like family member D , LPAM subunit alpha , VLA-4 receptor, alpha 4 subunit , VLA-4 subunit alpha , integrin alpha-4 , integrin alpha-IV , lymphocyte Peyer patch adhesion molecules subunit alpha , 269C wild type , antigen CD49D, alpha-4 subunit of VLA-4 receptor , integrin alpha 4 , integrin alpha-4 subunit , very late activation protein 4 receptor, alpha 4 subunit

GENE ID SPEZIES
100219853 Taeniopygia guttata
16401 Mus musculus
311144 Rattus norvegicus
3676 Homo sapiens
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