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anti-Mouse (Murine) Interleukin 6 Antikörper:
anti-Rat (Rattus) Interleukin 6 Antikörper:
anti-Human Interleukin 6 Antikörper:
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Human Monoclonal Interleukin 6 Primary Antibody für FACS - ABIN1383944
Lu, Brochier, Wijdenes, Brailly, Bataille, Klein: High amounts of circulating interleukin (IL)-6 in the form of monomeric immune complexes during anti-IL-6 therapy. Towards a new methodology for measuring overall cytokine production in human in vivo. in European journal of immunology 1992
Show all 60 Pubmed References
Mouse (Murine) Polyclonal Interleukin 6 Primary Antibody für WB - ABIN3042620
Xu, Feng, Wang, Zhu, Lin, Lou, Xiang, He, Zheng, Tang, Zuo: Phytoestrogen calycosin-7-O-?-D-glucopyranoside ameliorates advanced glycation end products-induced HUVEC damage. in Journal of cellular biochemistry 2011
Show all 19 Pubmed References
Rat (Rattus) Polyclonal Interleukin 6 Primary Antibody für WB - ABIN3042526
Liu, Shan, Dong, Liu, Ma, Liu: Combined early fluid resuscitation and hydrogen inhalation attenuates lung and intestine injury. in World journal of gastroenterology 2013
Show all 17 Pubmed References
Human Polyclonal Interleukin 6 Primary Antibody für WB - ABIN3043090
Qin, Ma, Yang, Hu, Zhou, Fu, Tian, Liu, Xu, Shen: A Triterpenoid Inhibited Hormone-Induced Adipocyte Differentiation and Alleviated Dexamethasone-Induced Insulin Resistance in 3T3-L1 adipocytes. in Natural products and bioprospecting 2015
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Mouse (Murine) Polyclonal Interleukin 6 Primary Antibody für ELISA, WB - ABIN3043248
Shi, Song, Zhang, Li, Li: Correlation between the microinflammatory state and left ventricular structural and functional changes in maintenance haemodialysis patients. in Experimental and therapeutic medicine 2013
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Human Polyclonal Interleukin 6 Primary Antibody für WB - ABIN3042806
Chen, Zhao, Wu, Zou, Luo, Li, Xie, Liang: The role of RIP1 and RIP3 in the development of aplastic anemia induced by cyclophosphamide and busulphan in mice. in International journal of clinical and experimental pathology 2015
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Human Polyclonal Interleukin 6 Primary Antibody für ICC, IF - ABIN269335
Bottino, Balamurugan, Tse, Thirunavukkarasu, Ge, Profozich, Milton, Ziegenfuss, Trucco, Piganelli: Response of human islets to isolation stress and the effect of antioxidant treatment. in Diabetes 2004
Show all 12 Pubmed References
Human Monoclonal Interleukin 6 Primary Antibody für CyTOF, FACS - ABIN4900155
Maneechotesuwan, Wamanuttajinda, Kasetsinsombat, Huabprasert, Yaikwawong, Barnes, Wongkajornsilp: Der p 1 suppresses indoleamine 2, 3-dioxygenase in dendritic cells from house dust mite-sensitive patients with asthma. in The Journal of allergy and clinical immunology 2009
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Human Monoclonal Interleukin 6 Primary Antibody für CyTOF, FACS - ABIN4900156
Rodier, Coppé, Patil, Hoeijmakers, Muñoz, Raza, Freund, Campeau, Davalos, Campisi: Persistent DNA damage signalling triggers senescence-associated inflammatory cytokine secretion. in Nature cell biology 2009
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Human Monoclonal Interleukin 6 Primary Antibody für FACS - ABIN4897267
Gironi, Saresella, Rovaris, Vaghi, Nemni, Clerici, Grossi: A novel data mining system points out hidden relationships between immunological markers in multiple sclerosis. in Immunity & ageing : I & A 2013
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The analysis points to a critical role for Hoxa9 (zeige HOXA9 Antikörper) and PU.1 in distal regulation of c-myb (zeige MYB Antikörper) expression in murine myeloid cells during iL-6-induced cell differentiation.
these findings suggested that IL6 gene deficiency antagonized HFD-induced bone loss.
Long-term exposure to atmospheric particulates, PM2.5 up-regulated H3K4 and H3K9 methylation in IL-6 and IFN-beta (zeige IFNB1 Antikörper) promoter regions through down-regulating Kdm6a (zeige KDM6A Antikörper) expression. The results suggest that short-term exposure to PM2.5 significantly enhances the survival rate of influenza A-contaminated mice, while long-term PM2.5 inhalation lowers the capacity of pulmonary macrophages to secrete IL-6 and IFN-beta (zeige IFNB1 Antikörper).
This study suggests direct stimulation of autophagy as a novel mechanism for IL-6-mediated protection of beta cells from stress-induced apoptosis.
Internalized CpG oligodeoxynucleotide (ODN)-conjugated PPMs (PPM-CpG) greatly enhance the induction of selected cytokines (TNF-alpha (zeige TNF Antikörper) and IL-6) in RAW 264.7 cells compared to that by the soluble CpG ODN and ionic complexes.
IL-6 is one of the factors produced by the elicited inflammatory response to HSV-1 infection contributing to nerve regression.
IL-6 likely up-regulates IRP1 (zeige ACO1 Antikörper) and DMT1 (zeige SLC11A2 Antikörper) expression and down-regulates FPN1 (zeige SLC40A1 Antikörper) expression in BV2 (zeige DNAH9 Antikörper) microglial cells through JNK (zeige MAPK8 Antikörper) signaling pathways
impact of IL-6 on the Th9/Th17 balance depending on the predominant cytokine milieu; data suggest that the IL-6-mediated reduction of Th2-related IL-4 leads to a decline of the Th9 immune response and allows Th17 differentiation
these results suggest that IL-23 (zeige IL23A Antikörper) plays a critical role in regulation of Th17 cytokines. Furthermore, IL-6 and TGF-beta (zeige TGFB1 Antikörper) do not appear to influence IL-23 (zeige IL23A Antikörper)-mediated restoration of Th17 cytokines after ethanol and burn injury.
IL-6 directly increases IL-10 (zeige IL10 Antikörper) production and participates in the counter-inflammatory response after acute kidney injury.
Among the Chinese population, IL-6 C-572G polymorphism is associated with susceptibility to moderate to late spontaneous preterm birth (SPTB (zeige SPTB Antikörper)).
findings suggested that CC genotype of IL-6 gene polymorphism is associated with serum IL-6 levels in obese polycystic ovary syndrome patients.
Targeting Stat3 (zeige STAT3 Antikörper)/Nrf2 (zeige GABPA Antikörper) pathway activated by PSC-secreted IL-6 may provide a novel therapeutic option to improve the prognosis of PDAC.
High IL6 expression is associated with breast cancer.
both IL-6 and RIG-I (zeige DDX58 Antikörper) are downstream molecules of STING along the DNA sensor pathway.
Plasma YKL-40 (zeige CHI3L1 Antikörper) and IL-6 had less diagnostic impact than CA 19.9
IL-6-stimulated MMP-13 (zeige MMP13 Antikörper) expression was independent of IL-1beta (zeige IL1B Antikörper) stimulation and was blocked by SAHA, suggesting that SAHA inhibits IL-6 signaling in Osteoarthritis (OA) chondrocytes.
In American cutaneous leishmaniasis caused by Leishmania braziliensis infection, MMP1 (zeige MMP1 Antikörper) is regulated by factors other than FLI1 (zeige FLI1 Antikörper), and the influence of IL-6 on MMP1 (zeige MMP1 Antikörper) was independent of its effect on FLI1 (zeige FLI1 Antikörper).
associations between the genetic variants and the LPS (zeige IRF6 Antikörper)-induced IL-6, IL-8 (zeige IL8 Antikörper), IL-10 (zeige IL10 Antikörper), IL-1ra (zeige IL1RN Antikörper) and TNF-alpha (zeige TNF Antikörper) cytokine levels were not significant in the meta-analysis. This present study does not support a strong genetic effect of LPS (zeige IRF6 Antikörper)-stimulated cytokine production; however, the potential for type II errors should be considered
IL-6 genotypes of rs1800795 GC and rs1800796 GG might point to a relatively high risk for T2D patients suffering from PDR in a Chinese population and they were associated with elevation of IL-6 expression in both mRNA and protein.
STA3 (zeige ARHGEF3 Antikörper) facilitates TLR4 (zeige TLR4 Antikörper)-dependent IL-6 and IL-8 (zeige IL8 Antikörper) production via IL-6 receptor-positive feedback in endometrial cells.
when a confluent endometrial epithelial cell barrier is faced with infection and damage, chemokines attract immune cells to the uterine lumen, but IL6 is solely secreted apically to ensure immune cells are only exposed to IL6 once they reach the lumen.
The results revealed that the peak expression of IL6 and 21 was on DPV 28 which correlated well with the FMDV antibody titer and plummeted to the prevaccination titer level by 60 DPV.
Exposure to follicular fluid transiently increased the transcript levels of IL8 (zeige IL8 Antikörper) and PTGS2 (zeige PTGS2 Antikörper), and decreased the expression of SOD2 (zeige SOD2 Antikörper), GPX3 (zeige GPX3 Antikörper), DAB2 (zeige DAB2 Antikörper), and NR3C1 (zeige NR3C1 Antikörper). TNF (zeige TNF Antikörper) and IL6 levels were also decreased while those of NAMPT (zeige NAMPT Antikörper) were unaffected.
Testicular IL-1 alpha (zeige IL1A Antikörper) and IL-1 beta (zeige IL1B Antikörper) concentrations were highest in the early post-natal period; however, IL-1 (zeige IL1A Antikörper) bioactivity and IL-6 concentrations were greatest in the immediate pre-pubertal period.
The results showed that the expression of TNF-alpha (zeige TNF Antikörper), iNOS (zeige NOS2 Antikörper), and IL-6 in alveolar macrophages was up-regulated by stimulation with the recombinant Mce4A protein of M. bovis; in contrast, expression of IL-12 (zeige IL12A Antikörper) was unaffected.[IL-6, IL-12 (zeige IL12A Antikörper)]
results show for the first time that interleukin-6 (IL6), in the presence of its soluble receptor (zeige IFNAR1 Antikörper) (sIL (zeige STIL Antikörper)-6R), induces activation of JAK1 (zeige JAK1 Antikörper), JAK2 (zeige JAK2 Antikörper), and STAT1 (zeige STAT1 Antikörper)/STAT3 (zeige STAT3 Antikörper) proteins in bovine articular chondrocytes.
Mechanical injury potentiates the catabolic effects of TNFalpha (zeige TNF Antikörper) and IL-6/sIL (zeige STIL Antikörper)-6R in causing proteoglycan (zeige Vcan Antikörper) degradation in human and bovine cartilage.
Mild heat shock increased the production of inflammatory cytokines, IL-1beta (zeige IL1B Antikörper) and IL-6 in rabbit cornea cells.
we showed that IL-6 did not directly promote the proliferation of theca interna cells.
Induction of ischemic osteonecrosis results in IL-6 production in the articular cartilage through an HIF-1 (zeige HIF1A Antikörper)-dependent pathway. IL-6 produced by hypoxic articular chondrocytes stimulates inflammatory cytokine responses in synovial cells.
The effects of semen, spermatozoa in extender, or extender alone on the expression of TGF-beta1 (zeige TGFB1 Antikörper), IL-10 (zeige IL10 Antikörper), and IL-6 in ovarian follicles are reported.
Data suggest IL6 prevents apoptosis in blastocysts (here, parthenotes) and enhances blastocyst viability via IL6/STAT3 (zeige STAT3 Antikörper) (signal transducer/activator of transcription (zeige STAT1 Antikörper) 3) signaling pathway (including up-regulation of STAT3 (zeige STAT3 Antikörper) expression/phosphorylation).
LIF (zeige LIF Antikörper) and IL-6 are important components of embryo-uterine interactions during early pregnancy in the pig, and may contribute to successful conceptus implantation.
INFgamma and IL-6 modulate PPARs gene expression in the porcine endometrium during the estrous cycle and pregnancy.
interleukin-6, endothelin ET-1 (zeige EDN1 Antikörper), and apoptotic Bak (zeige BAK1 Antikörper) and Bcl-XL (zeige BCL2L1 Antikörper) genes have roles in small bowel transplantation, in a swine model of ischemia and reperfusion injury
Data show that all five molecules, BNP (zeige BNC2 Antikörper), ICAM-1 (zeige ICAM1 Antikörper), TNF-alpha (zeige TNF Antikörper), VCAM-1 (zeige VCAM1 Antikörper) and IL-6, quickly and reliably signaled adverse interactions.
IL-6 level from frozen peripheral blood mononuclear cells was significantly lower than that from fresh ones.
These results suggest that TNF-alpha (zeige TNF Antikörper) and IL-10 (zeige IL10 Antikörper), but not IL-6, are involved in the late reparatory phases of the experimental disk lesion.
Plasma nitric oxide acts as a regulator of cytokine function exhibiting negative feedback to maintain steady plasma IL-6 concentration in protein- or energy-restricted goats during late gestation.
These data suggest that IL-6 may play a key role in equine metabolic syndrome (EMS), and that pro-inflammatory cytokines levels in serum may serve as an additional tool for diagnosing EMS.
IL-6 stimulation decreased chondrocyte expression of the canonical Wnt (zeige WNT2 Antikörper) signaling pathway transactivator beta-catenin (zeige CTNNB1 Antikörper), induced expression of inhibitors of the Wnt (zeige WNT2 Antikörper) pathway, and increased expression of GDF-5 (zeige GDF5 Antikörper).
study shows that IL-6 is rapidly induced in BAL-cells of airway-compromised horses in response to adenosine exposure, probably through A2BAR (zeige ADORA2B Antikörper) activation and that this effect can be modulated by A2AAR (zeige ADORA2A Antikörper)
Our data show the presence of a polymorphism downstream of the equine IL-6 gene that is associated with the basal Cu:Zn ratio in horses independent of breed.
Expression levels of IL-6 are significantly increased in peripheral blood mononuclear cells from trained horses compared to sedentary animals.
Failure of passive transfer may directly influence the serum IL-6 concentration in septic foals. Neither serum IL-6 nor IL-10 (zeige IL10 Antikörper) alone, were useful diagnostic indices of sepsis in equine neonates.
The contribution of bronchial epithelium to airway inflammation, with focus on mRNA and protein expression of IL-6, IL-10 (zeige IL10 Antikörper) and TNF-alpha (zeige TNF Antikörper), in horses with recurrent airway obstruction during exacerbation and in remission is reported.
IL6 mRNA abundance was significantly increased in spleen, liver, and gill of rainbow trout after experimental infection with Aeromonas salmonicida.
in this paper we present for the first time in fish the functional characterisation of IL-6, using rainbow trout
found that peptidoglycans derived from Gram-negative bacteria (Escherichia coli 0111:B4 and K12 (zeige KRT12 Antikörper)), are potent inducers of IL-1beta (zeige IL1B Antikörper) and IL-6 gene expression and were equal to, or more potent than, crude LPS (zeige IRF6 Antikörper).
This gene encodes a cytokine that functions in inflammation and the maturation of B cells. In addition, the encoded protein has been shown to be an endogenous pyrogen capable of inducing fever in people with autoimmune diseases or infections. The protein is primarily produced at sites of acute and chronic inflammation, where it is secreted into the serum and induces a transcriptional inflammatory response through interleukin 6 receptor, alpha. The functioning of this gene is implicated in a wide variety of inflammation-associated disease states, including suspectibility to diabetes mellitus and systemic juvenile rheumatoid arthritis.
B-cell hybridoma growth factor
, interleukin HP-1
, Interleukin 6 (interferon, beta 2)
, B-cell differentiation factor
, B-cell stimulatory factor 2
, CTL differentiation factor
, hybridoma growth factor
, interferon beta-2
, interleukin BSF-2
, interleukin-6 protein