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Human Endothelin 1 ELISA Kit für Competition ELISA - ABIN415024
Yang, Chen, Yuan, Fang, Cheng, Xia, Fang, Xu, Gao: Megakaryocytic leukemia 1 (MKL1) ties the epigenetic machinery to hypoxia-induced transactivation of endothelin-1. in Nucleic acids research 2013
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Rat (Rattus) Endothelin 1 ELISA Kit für Competition ELISA - ABIN416287
Xing, Zhang, Li, Huang, Luo, Hei, Xia, Gan: Pivotal role of mast cell carboxypeptidase A in mediating protection against small intestinal ischemia-reperfusion injury in rats after ischemic preconditioning. in The Journal of surgical research 2014
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Rat (Rattus) Endothelin 1 ELISA Kit für Sandwich ELISA - ABIN366462
Huang, Tang, Liang, Wen, Zhang, Xuan, Jian, Lin, Huang: The effects of 17-methoxyl-7-hydroxy-benzene-furanchalcone on the pressure overload-induced progression of cardiac hypertrophy to cardiac failure. in PLoS ONE 2014
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Mouse (Murine) Endothelin 1 ELISA Kit für Competition ELISA - ABIN415566
Song, Zhu, Li: Antifibrotic effects of crocetin in scleroderma fibroblasts and in bleomycin-induced sclerotic mice. in Clinics (São Paulo, Brazil) 2013
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Human Endothelin 1 ELISA Kit für Sandwich ELISA - ABIN455023
Ouyang, Li, Li, Cai, Chen, Chen, Chen, Yang, Xie: Mitochondrial ROS-K+ channel signaling pathway regulated secretion of human pulmonary artery endothelial cells. in Free radical research 2012
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Human Endothelin 1 ELISA Kit für Sandwich ELISA - ABIN1672856
Agapitov, Haynes: Role of endothelin in cardiovascular disease. in Journal of the renin-angiotensin-aldosterone system : JRAAS 2002
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Rat (Rattus) Endothelin 1 ELISA Kit für Sandwich ELISA - ABIN1672857
Liu, Zhu, Zhou, Wei, Long, Chen, Ling, Ge, Zhuo: Endoplasmic reticulum stress promotes amyloid-beta peptides production in RGC-5 cells. in Cell stress & chaperones 2014
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Mouse (Murine) Endothelin 1 ELISA Kit für Sandwich ELISA - ABIN1672858
Peng, Dai, Ji, Dai: The separate roles of endothelin receptors participate in remodeling of matrix metalloproteinase and connexin 43 of cardiac fibroblasts in maladaptive response to isoproterenol. in European journal of pharmacology 2010
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Human Endothelin 1 ELISA Kit für Sandwich ELISA - ABIN837829
Lacedonia, Valerio, Palladino, Carpagnano, Correale, Biase, Barbaro: Role of vasoactive intestinal Peptide in chronic obstructive pulmonary disease with pulmonary hypertension. in Rejuvenation research 2014
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Pig (Porcine) Endothelin 1 ELISA Kit für Competition ELISA - ABIN3155739
Gallinat, Efferz, Paul, Minor: One or 4 h of "in-house" reconditioning by machine perfusion after cold storage improve reperfusion parameters in porcine kidneys. in Transplant international : official journal of the European Society for Organ Transplantation 2014
Plasma ET-1 levels of rabbits increased significantly in fluorinated groups compared with those in the control group.
Dynamic monitoring and comparison of plasma levels of ET, CGRP, NO, and MDA as well as SOD activity revealed that appropriate intervention of these factors may reduce reperfusion injury
In a saline lavage-induced lung injury model, both circulatory and pulmonary ET-1 levels increased.
Data suggest elevated levels of endothelin-1, as exhibited in cardiovascular diseases, facilitate development of ventricular arrhythmia by steepening action potential duration restitution and by increasing beat-to-beat variability of repolarization.
High levels of ET-1 are closely associated with BBB (zeige ALMS1 ELISA Kits) disruption. ET-1 may play an important role in the pathogenesis of secondary brain injury after ICH (zeige ACE ELISA Kits).
After subarachnoid hemorrhage, the contractile response to ET-1 was enhanced, and the ET(A (zeige EDNRA ELISA Kits)) receptor expression was upregulated in the basilar artery.
After acute pulmonary thromboembolism, thrombolytic and anti-inflammatory treatment could decrease acute lung injury induced by ET-1 and NF-kappaB (zeige NFKB1 ELISA Kits) activation. [endothelin-1; NFKB]
The increase in myocardial distensibility induced by endothelin-1 is absent in heart failure and is dependent on nitric oxide and prostaglandin release.
Endothelin-1 enhances nuclear Ca2 (zeige CA2 ELISA Kits)+ transients in atrial myocytes through Ins (zeige INS ELISA Kits)(1,4,5)P3-dependent Ca2 (zeige CA2 ELISA Kits)+ release from perinuclear Ca2 (zeige CA2 ELISA Kits)+ stores
The enhancement of gap junction intercellular communication is activated by endothelin-1 via modulating the expression of connexin43 (zeige GJA1 ELISA Kits), and plays an important role in the pathogenesis of cerebral vasospasm
sub-vasomotor concentration of ET-1 leads to vascular dysfunction by impairing endothelium-dependent NO-mediated dilation via p38 (zeige MAPK14 ELISA Kits) kinase-mediated production of superoxide from NADPH oxidase (zeige NOX1 ELISA Kits) following ETA receptor activation
ET1 was lowest in kidneys removed from live pigs, greater in kidneys from pigs with brain death, and greatest in kidneys from pigs with cardiac arrest.
ET-1 contributes to formation of oedema during experimental sepsis by a novel mechanism involving increased HBP (zeige HEBP1 ELISA Kits) release from neutrophils.
Endothelin-1 expression is upregulated following therapeutic hypothermia after cardiac arrest.
ET-1 produces contraction of the urinary bladder neck muscles via muscular ET(A (zeige EDNRA ELISA Kits)) receptors coupled to extracellular Ca(2 (zeige CA2 ELISA Kits)+) entry via VOC (L-type) and non-VOC channels.
Endothelin-1 elevation is not only a conserved phenomenon in a pig traumatic brain injury (TBI) model, but it is a likely target for understanding the observed enhanced vascular response to TBI.
interleukin-6 (zeige IL6 ELISA Kits), endothelin ET-1, and apoptotic Bak (zeige BAK1 ELISA Kits) and Bcl-XL (zeige BCL2L1 ELISA Kits) genes have roles in small bowel transplantation, in a swine model of ischemia and reperfusion injury
ET-1 elicits a different pattern of Src (zeige SRC ELISA Kits) family kinase (SFK) activation and might trigger a different pattern of SFK activation from that caused by ATP and UTP.
Compared with the untreated group, the levels of serum ET-1 after acute myocardial infarction and reperfusion were significantly decreased in the Xuefu Zhuyu-treated group.
study suggests a possible role for endothelin-1(resulting from the actions of endothelin-converting enzyme-1 (zeige ECE1 ELISA Kits)) acting via endothelin receptor A (zeige EDNRA ELISA Kits) in the control of luteolytic sensitivity in the pig
ET-1 increased NSCLC clonal growth, whereas BQ123, ZD4054, lapatinib or gefitinib inhibited proliferation. The results indicate that ET-1 may regulate NSCLC cellular proliferation in an EGFR (zeige EGFR ELISA Kits)- and HER2 (zeige ERBB2 ELISA Kits)-dependent manner
Data indicate that patients with systemic sclerosis (SSc (zeige CYP11A1 ELISA Kits)) displayed higher serum levels of VEGF (zeige VEGFA ELISA Kits), endothelin-1 and s-Fractalkine (zeige CX3CL1 ELISA Kits), and that the s-Fractalkine (zeige CX3CL1 ELISA Kits) levels positively correlated with CD34 (zeige CD34 ELISA Kits)(+)CD45 (zeige PTPRC ELISA Kits)(-) endothelial progenitor cells (EPC (zeige TCF21 ELISA Kits)) numbers.
Endothelin-1 and its receptors on haemorrhoidal tissue: a potential site for therapeutic intervention
we could provide evidence that established stress-related biomarkers ET-1, MCP-1 (zeige CCL2 ELISA Kits), CGA (zeige CGA ELISA Kits) were differentially regulated among patients with AF compared to healthy controls.
Two END1 (zeige VPS11 ELISA Kits) polymorphisms do not appear to affect the development of hypertension in the Chinese population.
TWEAK (zeige TNFSF12 ELISA Kits) may stimulate endothelial ET-1 synthesis, through the up-regulation of ECE-1 (zeige ECE1 ELISA Kits).
ET-1 may be a unique predictor of heart failure prognosis
The EDNRA (zeige EDNRA ELISA Kits) SNP rs5335 was independently associated with aneurysms >/=7 mm in size at the time of rupture. Patients with cerebral aneurysms also carrying the G allele of EDNRA (zeige EDNRA ELISA Kits) SNP rs5335 may develop larger aneurysms before rupture.
c-Src tyrosine kinase (zeige CSK ELISA Kits) mediates high glucose-induced endothelin-1 expression
Endothelin contributes to the rise in SBP (zeige SHBG ELISA Kits) in response to acute hypoxia in patients with severely untreated OSA.
SIX1 (zeige SIX1 ELISA Kits) regulates dorsal arch development not only by inducing dorsal Jag1 (zeige JAG1 ELISA Kits) expression but also by inhibiting endothelin 1 (Edn1) expression in the pharyngeal endoderm of the dorsal arch, thus preventing dorsal EDNRA (zeige EDNRA ELISA Kits) signaling.
NOX4 (zeige NOX4 ELISA Kits)-derived reactive oxygen species in general, and possibly superoxide in particular, are involved in flow-stimulated inner medullary collecting duct ET-1 production.
in normal tissues the tandem of serine carboxypeptidases, Scpep1 (zeige SCPEP1 ELISA Kits) and CathA likely constitutes an important part of the physiological mechanism responsible for the balanced elimination of heightened levels of ET-1 that otherwise would accumulate in tissues and consequently contribute to development of the hyper-proliferative corneal dystrophy and abnormal skin thickening
Newborn endothelial cells express high levels of ET-1 peptides, rapidly release ET-1 in response to endothelial stimulation, and initiate ET-1-mediated endothelium-dependent constriction
cellular and molecular mechanisms of ET-1 action in periodontitis
Taken together, these data indicate that during high-salt feeding, the autocrine actions of ET-1 via upregulation of the ETB (zeige EDNRB ELISA Kits) receptor are critical for IMCD NO production, facilitating inhibition of ion reabsorption.
reduced lung levels of PPARgamma (zeige PPARG ELISA Kits) and increased levels of microRNA-27a (miR (zeige MLXIP ELISA Kits)-27a), v-ets (zeige ETS1 ELISA Kits) avian erythroblastosis virus E26 oncogene (zeige RAB1A ELISA Kits) homolog 1 (ETS1 (zeige ETS1 ELISA Kits)), endothelin-1 (ET-1), and markers of endothelial dysfunction (platelet/endothelial cell adhesion molecule 1 (zeige PECAM1 ELISA Kits) and E selectin (zeige SELE ELISA Kits)).
Increased circulating Edn1 and expression of Ednra (zeige EDNRA ELISA Kits) in endothelial cells are characteristic of diabetic kidney disease-susceptible mice.
Phylogenetic analysis of conserved grhl (zeige GHRL ELISA Kits)-binding sites in gene regulatory regions identified endothelin-1 (edn1) as a putative direct grhl3 (zeige GRHL3 ELISA Kits) target gene, and this was confirmed by chromatin precipitation assays in embryos.
EDN1 plays an important role in hepatocellular carcinoma progression by activating the PI3K/AKT pathway and is regulated by miR-1.
Data suggest that edn1/ednraa (zeige EDNRA ELISA Kits) (endothelin-1/endothelin-1 receptor type A (zeige EDNRA ELISA Kits)) signaling is involved in acid-base regulation and transepithelial proton secretion via vacuolar proton-translocating ATPase (zeige DNAH8 ELISA Kits) in zebrafish embryonic skin.
These findings point to complexity of regulation by edn1 and hand2 at the earliest stages of pharyngeal arch development, in which control of growth and morphogenesis can be genetically separated.
Endothelin 1 combines with Bone Morphogenetic Proteins to pattern the dorsal-ventral axis of the craniofacial skeleton.
activation of Endothelin-1 signaling in craniofacial patterning
Edn1 from the pharyngeal ectoderm signals through Ednra (zeige EDNRA ELISA Kits) proteins to direct early dorsoventral patterning of the skeletogenic neural crest.
The role of endothelin-1 and light in the regulation of melanopsins and the clock proteins in an embyronic cell line is reported.
EDN-1 may be involved in the protection of sperm from phagocytosis by polymorphonuclear neutrophils in the bovine oviduct, supporting sperm survival until fertilization
Data suggest that, in Fallopian tubes, endothelins (EDN1, EDN2 (zeige EDN2 ELISA Kits), EDN3 (zeige EDN3 ELISA Kits)) and EDN (zeige RNASE2 ELISA Kits)-converting enzymes (ECE1 (zeige ECE1 ELISA Kits), ECE2 (zeige ECE2 ELISA Kits)) are expressed in epithelial cells; EDN (zeige RNASE2 ELISA Kits) receptors (EDNRA (zeige EDNRA ELISA Kits), EDNRB (zeige EDNRB ELISA Kits)) are present in smooth-muscle. Expression of EDN1, EDN2 (zeige EDN2 ELISA Kits), and ECE2 (zeige ECE2 ELISA Kits) is highest on day of ovulation. EDN (zeige RNASE2 ELISA Kits)/ENDR signaling appears to participate Fallopian tube function. These studies were conducted in Holstein cows.
results suggest that ET-1-induced activation of proMMP-2 is mediated via cross-talk between NADPH oxidase (zeige NOX1 ELISA Kits)-PKCalpha (zeige PKCa ELISA Kits)-p(38)MAPK (zeige MAPK1 ELISA Kits) and NFkappaB-MT1MMP (zeige MMP14 ELISA Kits) signaling pathways along with a marked decrease in TIMP-2 (zeige TIMP2 ELISA Kits) expression in the cells
We demonstrated that (i) treatment of bovine pulmonary artery smooth muscle cells with ET-1 stimulates cPLA2 (zeige PLA2G4A ELISA Kits) activity in the cell membrane.
Differential cell-specific and spatiotemporal expression of the EDN1 system and NOS (zeige NOS ELISA Kits) in the bovine utero-placental unit may be associated with regulation of vascular and cellular functions during pregnancy.
Oxidized LDL is a stimulus of ET-1 production in cultured vascular endothelial cells.
Endothelin-1 decreases ethanolamine plasmalogen levels and evokes platelet-activating factor production in brain microvessels
prostaglandin F2alpha, endothelin-1, and angiotensin II may interact with each other in a local positive feedback manner to activate their secretion in the regressing corpus luteum, thus accelerating and completing luteolysis
LOX-1 (zeige OLR1 ELISA Kits) and CD40 (zeige CD40 ELISA Kits) synergistically, but through a distinct pathway, work to induce endothelin-1 expression in endothelial cells.
Elevated local expression of ET-1 and Ednra/Ednrb (zeige EDNRB ELISA Kits) during the peri (zeige PLIN1 ELISA Kits)-ovulatory period induces the high contractile activity of the oviduct to optimize gamete transport.
Short-term hyperinsulinaemia leads to increased vascular resistance in the equine digit and increased expression of ET-1 in the laminar tissue.
This is the first report describing the cDNA encoding preproendothelin-1 in an amphibian species.
A new role for et-1 signaling during early neural crest specification is reported.
The protein encoded by this gene is proteolytically processed to release a secreted peptide termed endothelin 1. This peptide is a potent vasoconstrictor and is produced by vascular endothelial cells. Endothelin 1 also can affect the central nervous system. Two transcript variants encoding different isoforms have been found for this gene.
, gene for endothelin
, endothelin 1
, preproendothelin 1
, endothelin 1 L homeolog