anti-Meerschweinchen Achaete-Scute Complex Homolog 1 (Drosophila) Antikörper für Western Blotting

Recommended Achaete-Scute Complex Homolog 1 (Drosophila) Antibody (geliefert von: Anmelden zum Anzeigen )

Antigen
Achaete-Scute Complex Homolog 1 (Drosophila) (ASCL1) Antikörper
  • ASH1
  • HASH1
  • MASH1
  • bHLHa46
  • AI225900
  • Mash1
  • ASCL1
  • Xash1
  • ascl1-A
  • achaete-scute family bHLH transcription factor 1
  • achaete-scute family bHLH transcription factor 1 L homeolog
  • achaete-scute complex homolog 1
  • ASCL1
  • Ascl1
  • ascl1.L
  • LOC100220505
Epitop
N-Term
34
28
20
15
15
8
7
5
4
3
3
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
Reaktivität
Rind (Kuh), Hund, Meerschweinchen, Human, Maus, Kaninchen, Ratte (Rattus)
148
80
41
8
6
6
6
4
4
3
1
1
Wirt
Kaninchen
135
16
3
3
Klonalität
Polyklonal
Konjugat
Unkonjugiert
10
10
10
8
8
8
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Applikation
Immunohistochemistry (IHC), Western Blotting (WB)
129
90
54
26
17
15
13
3
1
1
1
Optionen
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Bilder

Produktnummer ABIN2779585
$ 229.00
Zzgl. Versandkosten $45.00
Relevance Score ABIN Application Konjugat Host Isotype Epitope Hersteller Clonality References Details
3.0849469 ABIN2792096 WB Rabbit Middle Region Anmelden zum Anzeigen Polyclonal 1
3.0849469 ABIN2777176 WB Rabbit N-Term Anmelden zum Anzeigen Polyclonal
1 ABIN202101 IHC (p) WB Rabbit IgG AA 48-97 Anmelden zum Anzeigen Polyclonal
1 ABIN470355 WB Rabbit C-Term Anmelden zum Anzeigen Polyclonal
1 ABIN5516449 WB Rabbit N-Term Anmelden zum Anzeigen Polyclonal
1 ABIN1836787 WB Rabbit AA 50-99 Anmelden zum Anzeigen Polyclonal

General

Antigen Achaete-Scute Complex Homolog 1 (Drosophila) (ASCL1) Antikörper
Epitop N-Term
(34), (28), (20), (15), (15), (8), (7), (5), (4), (3), (3), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reaktivität Rind (Kuh), Hund, Meerschweinchen, Human, Maus, Kaninchen, Ratte (Rattus)
(148), (80), (41), (8), (6), (6), (6), (4), (4), (3), (1), (1)
Wirt Kaninchen
(135), (16), (3), (3)
Klonalität
Polyklonal
Konjugat Unkonjugiert
(10), (10), (10), (8), (8), (8), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Applikation Immunohistochemistry (IHC), Western Blotting (WB)
(129), (90), (54), (26), (17), (15), (13), (3), (1), (1), (1)
Pubmed 3 Publikationen vorhanden
Hersteller Anmelden zum Anzeigen

Produktdetails

Antigendetails Anwendungsinformationen Handhabung Referenzen Bilder
Sequenz QSAQQQQQQQ QQQQQAPQLR PAADGQPSGG GHKSAPKQVK RQRSSSPELM
Homologie Cow: 100%, Dog: 92%, Guinea Pig: 100%, Human: 100%, Mouse: 92%, Rabbit: 92%, Rat: 92%
Produktmerkmale This is a rabbit polyclonal antibody against ASCL1. It was validated on Western Blot and immunohistochemistry.
Reinigung Protein A purified
Immunogen The immunogen is a synthetic peptide directed towards the N terminal region of human ASCL1

Antigendetails

Produktdetails Anwendungsinformationen Handhabung Referenzen Bilder zurück nach oben
Antigen
Andere Bezeichnung ASCL1 (ASCL1 Antibody Abstract)
Hintergrund ASCL1 encodes a member of the basic helix-loop-helix (BHLH) family of transcription factors. The protein activates transcription by binding to the E box (5'-CANNTG-3'). Dimerization with other BHLH proteins is required for efficient DNA binding. This protein plays a role in the neuronal commitment and differentiation and in the generation of olfactory and autonomic neurons. It is highly expressed in medullary thyroid cancer and small cell lung cancer and may be a useful marker for these cancers.
Alias Symbols: ASH1, HASH1, MASH1, bHLHa46
Protein Interaction Partner: MEF2D, MEF2C, MEF2A, NEUROG2, UBQLN1, EP300, TCF4, BMP2, ASCL1,
Protein Size: 236
Molekulargewicht 25 kDa
Gen-ID 429
NCBI Accession NM_004316, NP_004307
UniProt P50553
Pathways Dopaminergic Neurogenesis

Anwendungsinformationen

Produktdetails Antigendetails Handhabung Referenzen Bilder zurück nach oben
Applikationshinweise Optimal working dilutions should be determined experimentally by the investigator.
Kommentare

Antigen size: 236 AA

Beschränkungen Nur für Forschungszwecke einsetzbar

Handhabung

Produktdetails Antigendetails Anwendungsinformationen Referenzen Bilder zurück nach oben
Format Liquid
Konzentration Lot specific
Buffer Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Konservierungsmittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung Avoid repeated freeze-thaw cycles.
Lagerung -20 °C
Informationen zur Lagerung For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen

Produktdetails Antigendetails Anwendungsinformationen Handhabung Bilder zurück nach oben
Produkt verwendet in:

Suozzi, Malatesta, Zancanaro: "Subcellular distribution of key enzymes of lipid metabolism during the euthermia-hibernation-arousal cycle." in: Journal of anatomy, Vol. 214, Issue 6, pp. 956-62, 2009

Vias, Massie, East, Scott, Warren, Zhou, Nikitin, Neal, Mills: "Pro-neural transcription factors as cancer markers." in: BMC medical genomics, Vol. 1, pp. 17, 2008

Allgemeine Veröffentlichungen

Somasundaram, Reddy, Vinnakota, Britto, Subbarayan, Nambiar, Hebbar, Samuel, Shetty, Sreepathi, Santosh, Hegde, Hegde, Kondaiah, Rao: "Upregulation of ASCL1 and inhibition of Notch signaling pathway characterize progressive astrocytoma." in: Oncogene, Vol. 24, Issue 47, pp. 7073-83, 2005

Bilder

Produktdetails Antigendetails Anwendungsinformationen Handhabung Referenzen zurück nach oben
Bilder des Herstellers
Immunohistochemistry (IHC) image for anti-Achaete-Scute Complex Homolog 1 (Drosophila) (ASCL1) (N-Term) antibody (ABIN2779585) anti-Achaete-Scute Complex Homolog 1 (Drosophila) (ASCL1) (N-Term) antibody
Immunohistochemistry (IHC) image for anti-Achaete-Scute Complex Homolog 1 (Drosophila) (ASCL1) (N-Term) antibody (ABIN2779585) Human kidney
Western Blotting (WB) image for anti-Achaete-Scute Complex Homolog 1 (Drosophila) (ASCL1) (N-Term) antibody (ABIN2779585) WB Suggested Anti-ASCL1
Antibody Titration: 1.25 µg/mL
Positive Control...