RAD51 (RAD51) ELISA Kits

Bezeichnung:
DNA Repair Protein Homolog 1 ELISA Kits (RAD51)
Auf www.antikoerper-online.de finden Sie aktuell 6 DNA Repair Protein Homolog 1 (RAD51) ELISA Kits von 4 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen RAD51 Antikörper (198) und RAD51 Proteine (13) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 238 RAD51 Produkte verfügbar.
Synonyme:
4921524O04Rik, 8030409M04Rik, ATRAD51, AV304093, brcc5, CRAD51, F22D1.20, F22D1_20, HRAD51, HsRad51, HsT16930, MRMV2, rad51, rad51a, RAS associated with diabetes protein 51, reca, RGD1563603, wu:fb38e12, xrad51, zgc:77754
list all ELISA KIts Gen GeneID UniProt
RAD51 57434 Q9CX47
RAD51 5888 Q06609
Ratte RAD51 RAD51 499870  

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RAD51 (RAD51) ELISA Kits nach Reaktivitäten

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Weitere ELISA Kits für RAD51 Interaktionspartner

Mouse (Murine) DNA Repair Protein Homolog 1 (RAD51) Interaktionspartner

  1. Our results thus help establish the functional relevance of the trimeric RAD51-SWI5 (zeige SWI5 ELISA Kits)-SFR1 (zeige SFR1 ELISA Kits) complex and provide insights into the mechanistic underpinnings of homology-directed DNA repair in mammalian cells.

  2. Unlike directly induced DSBs, secondary DSBs were not efficiently repaired, although Rad51 and 53BP1 (zeige TP53BP1 ELISA Kits) were recruited to these sites. H2AX (zeige H2AFX ELISA Kits) was dramatically stabilized in response to DSBs directly caused by gamma-rays, enabling gammaH2AX (zeige H2AFX ELISA Kits) foci formation and DSB repair, whereas H2AX (zeige H2AFX ELISA Kits) was barely stabilized in response to secondary DSBs, in which gammaH2AX (zeige H2AFX ELISA Kits) foci were small and DSBs were not efficiently repaired

  3. HOP2 (zeige PSMC3IP ELISA Kits)-MND1 (zeige MND1 ELISA Kits) enhances the interaction of RAD51 with nucleotide cofactors and modifies its DNA-binding specificity.

  4. Rad51 repaired DNA damage.

  5. BRCA2 (zeige BRCA2 ELISA Kits)-mediated sequestration of nuclear RAD51 serves to prevent inappropriate DNA interactions.

  6. increased Rad51 concentration and homology length interact synergistically to promote 3' extension, presumably as a result of enhanced Brca2 (zeige BRCA2 ELISA Kits)-mediated Rad51 polymerization

  7. Results suggest that cellular levels of Brca2 (zeige BRCA2 ELISA Kits) and Rad51 are mutually dependent on each other, and that low levels of these proteins provide selective pressure for reduction of p53 (zeige TP53 ELISA Kits), which permits cell growth

  8. FBH1 (zeige FBXO18 ELISA Kits) restraining RAD51 DNA binding under unperturbed growth conditions to prevent unwanted or unscheduled DNA recombination.

  9. HELQ (zeige HEL308 ELISA Kits) interacts directly with the RAD51 paralogue complex BCDX2 and functions in parallel to the Fanconi anaemia pathway to promote efficient homologous recombination at damaged replication forks

  10. RAD51 recombinase (zeige RAG1 ELISA Kits) inhibitor overcomes imatinib-resistance in chronic myeloid leukaemia.

Arabidopsis thaliana DNA Repair Protein Homolog 1 (RAD51) Interaktionspartner

  1. The authors find that RBR1 is also required for RAD51 localization to DNA lesions.

  2. RAD51 forms a protein complex with AtRAD51C (zeige RAD51C ELISA Kits)-AtXRCC3 to facilitate RAD51 localization on chromosomes for meiotic recombination.

  3. Our data demonstrate that RAD51 plays a supporting role for DMC1 (zeige DMC1 ELISA Kits) in meiotic recombination in the flowering plant, Arabidopsis.

  4. The present study demonstrates for the first time the involvement of a host RAD51 protein in mungbean yellow mosaic India virus replication.

  5. Results demonstrate that DMC1 functions independently and spatially separated from RAD51 during meiosis and that ATR is an integral part of the regular meiotic program.

  6. Establishment and stabilisation of pairing of homologous centromeric and pericentromeric regions depends principally upon DMC1 (zeige DMC1 ELISA Kits), while pairing and synapsis of euchromatic chromosome arms of homologues requires the presence of RAD51

  7. AtRAD51 is required to ensure the fidelity of homologous recombination during interchromosomal exchanges. It may also be required to ensure the fidelity of homologous recombination in the interchromosomal exchanges initiated by AtDMC1.

  8. AtBRCA2 is required for proper meiotic synapsis and mediates the recruitment of AtRAD51 and AtDMC1.

  9. Study provides the molecular evidence showing that the BRCA2 (zeige BRCA2 ELISA Kits)-RAD51 complex, known for its function in HR, also plays a direct and specific role in transcription regulation during plant immune responses.

  10. results show that loss of RAD51 caused hypersensitivity to the double-strand break-inducing agent bleomycin in P. patens but not Arabidopsis; data show importance of RAD51 for viability is independent of taxonomic position or complexity of an organism

Pig (Porcine) DNA Repair Protein Homolog 1 (RAD51) Interaktionspartner

  1. The complete cDNA sequences of the pig RAD51, RAD52 (zeige RAD52 ELISA Kits), and RAD54 (zeige RAD54L ELISA Kits) genes, which are closely related to homologous recombination events, arae identified using molecular cloning technique in pigs.

Cow (Bovine) DNA Repair Protein Homolog 1 (RAD51) Interaktionspartner

  1. Meiosis progression and female age affect expression profile of DNA repair RAD51 gene in bovine oocytes.

  2. RAD51 plays a crucial role in halting cell death program induced by ionizing radiation in bovine oocytes.

Human DNA Repair Protein Homolog 1 (RAD51) Interaktionspartner

  1. Upregulation of RAD51 and overexpression of Ki67 (zeige MKI67 ELISA Kits) may be associated with the progression of thyroid cancer.

  2. The data suggest that Rad51 overexpression is correlated with malignant phenotypes of colorectal cancer and may predict poor prognosis for these patients.

  3. Data suggest that RAD51, BRCA2 (zeige BRCA2 ELISA Kits), and BRCA1 promote stability of nascent DNA at replication forks; RAD51 prevents MRE11 (zeige MRE11A ELISA Kits) nuclease (zeige DCLRE1C ELISA Kits)-mediated degradation of nascent ssDNA; BRCA2 (zeige BRCA2 ELISA Kits) displaces RPA (zeige RPA1 ELISA Kits) (replication protein A) complex by recruiting RAD51 to protect ssDNA; BRCA1 promotes repair foci following DNA damage and is essential for cell survival. (BRCA = breast cancer recombination protein; RAD51 = Rad51 recombinase (zeige RAG1 ELISA Kits)) [REVIEW]

  4. Data suggest RAD52 (zeige RAD52 ELISA Kits) binds tightly to RPA (zeige RPA1 ELISA Kits)/ssDNA complex in presynaptic complex and inhibits RPA (zeige RPA1 ELISA Kits) turnover; during presynaptic complex assembly, most of RPA (zeige RPA1 ELISA Kits) and RAD52 (zeige RAD52 ELISA Kits) is displaced from ssDNA, but some RAD52 (zeige RAD52 ELISA Kits)/RPA (zeige RPA1 ELISA Kits)/ssDNA complexes persist as interspersed clusters surrounded by RAD51 filaments. (RAD52 (zeige RAD52 ELISA Kits) = Rad52 (zeige RAD52 ELISA Kits) DNA repair/recombination protein (zeige RAD50 ELISA Kits); RPA (zeige RPA1 ELISA Kits) = replication protein A; ssDNA = single-stranded DNA; RAD51 = Rad51 recombinase (zeige RAG1 ELISA Kits))

  5. High RAD51 expression is associated with drug Resistance in Malignant Melanoma.

  6. Cryo-EM analyses of human RAD51 in different states of the DNA-strand-exchange process and structures of presynaptic and postsynaptic complexes of RAD51 at near-atomic resolution.

  7. By specifically regulating RAD51 activity at uncoupled replication forks, MMS22L (zeige MMS22L ELISA Kits)-TONSL (zeige NFKBIL2 ELISA Kits) stabilizes perturbed replication forks by promoting replication fork reversal and stimulating their homologous recombination-mediated restart in vivo.

  8. S100A11 (zeige S100A11 ELISA Kits) is involved in homologous recombination by regulating the appearance of RAD51 in double strand break repair sites.

  9. HsRAD51 NPF which may form on nucleosome bound dsDNA can have profound effects on the dynamic nature of nucleosomes, and may even facilitate the recruitment of other factors such as homologous HsRAD51-ssDNA NPFs or HsRAD54.

  10. ubiquitination of RAD51 hinders RAD51-BRCA2 (zeige BRCA2 ELISA Kits) interaction, while deubiquitination of RAD51 facilitates RAD51-BRCA2 (zeige BRCA2 ELISA Kits) binding and RAD51 recruitment and thus is critical for proper homologous recombination

Xenopus laevis DNA Repair Protein Homolog 1 (RAD51) Interaktionspartner

  1. Data show that MRE11 (zeige MRE11A ELISA Kits)- and RAD51-dependent fork repair leading to reloading of the GINS onto the MCM-CDC45 complex still engaged with the DNA could be sufficient to restore a functional CDC45-MCM-GINS (CMG (zeige CASK ELISA Kits)) helicase (zeige DNA2 ELISA Kits) complex.

  2. By promoting CtIP (zeige RBBP8 ELISA Kits)-dependent resection of double-strand break (DSB) ends while preventing Rad51 chromatin assembly, Cdk1 (zeige CDK1 ELISA Kits) inhibits both the nonhomologous and homologous modes of DSB repair during mitosis.

  3. Rad51 has a role at the replication fork protecting DNA from Mre11 (zeige MRE11A ELISA Kits)-dependent degradation.

RAD51 Antigen-Profil

Beschreibung des Gens

The protein encoded by this gene is a member of the RAD51 protein family. RAD51 family members are highly similar to bacterial RecA and Saccharomyces cerevisiae Rad51, and are known to be involved in the homologous recombination and repair of DNA. This protein can interact with the ssDNA-binding protein RPA and RAD52, and it is thought to play roles in homologous pairing and strand transfer of DNA. This protein is also found to interact with BRCA1 and BRCA2, which may be important for the cellular response to DNA damage. BRCA2 is shown to regulate both the intracellular localization and DNA-binding ability of this protein. Loss of these controls following BRCA2 inactivation may be a key event leading to genomic instability and tumorigenesis. Multiple transcript variants encoding different isoforms have been found for this gene.

Alternative names and synonyms associated with RAD51

  • X-ray repair complementing defective repair in Chinese hamster cells 2 (Xrcc2) Elisa Kit
  • DNA repair protein RAD51-like 1 (RAD51) Elisa Kit
  • RAD51 homolog (Rad51) Elisa Kit
  • RAD51 homolog (RecA homolog, E. coli) (S. cerevisiae) (rad51) Elisa Kit
  • RAD51 homolog (S. cerevisiae) (RAD51) Elisa Kit
  • RAD51 homolog (S. cerevisiae) (Rad51) Elisa Kit
  • RAD51 recombinase (RAD51) Elisa Kit
  • RAD51 recombinase (Rad51) Elisa Kit
  • RAD51 recombinase (rad51-a) Elisa Kit
  • 4921524O04Rik Elisa Kit
  • 8030409M04Rik Elisa Kit
  • ATRAD51 Elisa Kit
  • AV304093 Elisa Kit
  • brcc5 Elisa Kit
  • CRAD51 Elisa Kit
  • F22D1.20 Elisa Kit
  • F22D1_20 Elisa Kit
  • HRAD51 Elisa Kit
  • HsRad51 Elisa Kit
  • HsT16930 Elisa Kit
  • MRMV2 Elisa Kit
  • rad51 Elisa Kit
  • rad51a Elisa Kit
  • RAS associated with diabetes protein 51 Elisa Kit
  • reca Elisa Kit
  • RGD1563603 Elisa Kit
  • wu:fb38e12 Elisa Kit
  • xrad51 Elisa Kit
  • zgc:77754 Elisa Kit

Bezeichner auf Proteinebene für RAD51

DNA repair protein XRCC2 , X-ray repair cross-complementing protein 2 , recA/RAD51 family protein , DNA repair protein RAD51 homolog 1 , RAD51 homolog A , RAD51 homolog (RecA homolog, E. coli) , homolog to S.cerevisiae , DNA repair protein RAD51 , DNA repair protein RAD51-like 1 , BRCA1/BRCA2-containing complex, subunit 5 , RecA, E. coli, homolog of , RecA-like protein , recombination protein A , RAD51 homolog , DNA repair protein RAD51 homolog A , RAD51 homolog (RecA homolog) , XRad51.1

GENE ID SPEZIES
57434 Mus musculus
832208 Arabidopsis thaliana
19361 Mus musculus
406487 Danio rerio
396086 Gallus gallus
403568 Canis lupus familiaris
100141309 Sus scrofa
514749 Bos taurus
100008661 Oryctolagus cuniculus
100689324 Cricetulus griseus
5888 Homo sapiens
499870 Rattus norvegicus
397726 Xenopus laevis
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