OGG1 Proteine (OGG1)

Bezeichnung:
8-Oxoguanine DNA Glycosylase Proteine (OGG1)
Auf www.antikoerper-online.de finden Sie aktuell 15 8-Oxoguanine DNA Glycosylase (OGG1) Proteine von 7 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen OGG1 Antikörper (148) und OGG1 Kits (18) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 188 OGG1 Produkte verfügbar.
Synonyme:
8-oxoguanine-DNA glycosylase 1, 19.m02329, ARABIDOPSIS 8-OXOGUANINE-DNA GLYCOSYLASE 1, ATOGG1, DDBDRAFT_0184479, DDBDRAFT_0233024, DDB_0184479, DDB_0233024, F8K7.14, F8K7_14, HMMH, HOGG1, Mmh, MUTM, ogg1, OGH1, Tb04.1H19.930, zgc:158858
alle Proteine anzeigen Gen GeneID UniProt
OGG1 4968 O15527
Ratte OGG1 OGG1 81528 O70249
OGG1 18294 O08760

Weitere Synonyme anzeigen

OGG1 Proteine (OGG1) nach Spezies

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Am meisten referenzierte OGG1 Proteine

  1. Human OGG1 Protein expressed in Escherichia coli (E. coli) - ABIN667178 : Mirbahai, Kershaw, Green, Hayden, Meldrum, Hodges: Use of a molecular beacon to track the activity of base excision repair protein OGG1 in live cells. in DNA repair 2010 (PubMed)
    Zeige alle 2 Referenzen für 667178

Weitere Proteine zu OGG1 Interaktionspartnern

Xenopus laevis 8-Oxoguanine DNA Glycosylase (OGG1) Interaktionspartner

  1. OGG1 activity might be inhibited during postreplicative mismatch repair.

Zebrafish 8-Oxoguanine DNA Glycosylase (OGG1) Interaktionspartner

  1. Results show ogg1 is fundamentally required for protecting the developing brain, which may be helpful in understanding the aetiology of congenital brain deficits.

  2. work demonstrates the requirement of ogg1 in cardiac progenitors and heart development in zebrafish

Arabidopsis thaliana 8-Oxoguanine DNA Glycosylase (OGG1) Interaktionspartner

  1. Arabidopsis cells use both FPG and OGG1 to repair 8-oxoG in a pathway that requires ZDP and ARP (zeige ARFRP1 Proteine) in downstream steps.

  2. Overexpression of OGG1 enhances seed longevity and abiotic stress tolerance.

Human 8-Oxoguanine DNA Glycosylase (OGG1) Interaktionspartner

  1. The interaction of OGG1 and XRCC1 (zeige XRCC1 Proteine) DNA repair polymorphisms and arsenic exposure enhances telomeric DNA damage.

  2. Polymorphisms of OGG1 and MTHFR (zeige MTHFR Proteine) genes are associated with ARC (zeige NOL3 Proteine) susceptibility

  3. Reduced MUTYH (zeige MUTYH Proteine), MTH1 (zeige NUDT1 Proteine), and OGG1 expression and TP53 (zeige TP53 Proteine) mutations occur in diffuse-type adenocarcinoma of gastric cardia.

  4. These results together, points to a new paradigm about the role of DNA damage and repair by OGG1 in aging and age-associated disease processes.

  5. DNA repair protein (zeige ATRIP Proteine) OGG1 bound to its substrate is coupled to DNA occupancy of NF-kappaB (zeige NFKB1 Proteine) and functions in epigenetic regulation of gene expression.

  6. Study shows increased level of 8-oxoG and decreased OGG1 protein in the serum of patients with Alzheimer's disease, suggesting that oxidative damage to DNA and a decreased DNA glycosylase are involved in the etiopathology of Alzheimer's disease

  7. APE1 (zeige APEX1 Proteine) Accelerates turnover of OGG1 by preventing retrograde binding to the abasic-site product.

  8. find that the energetic nature of the observed binding free energies of human 8-oxoguanine DNA glycosylase (hOGG1) and human uracil DNA glycosylase (zeige UNG Proteine) (hUNG) for undamaged DNA are derived from different sources. Although hOGG1 uses primarily nonelectrostatic binding interactions with nonspecific DNA, hUNG uses a salt-dependent electrostatic binding mode

  9. The Cys/Cys (zeige DNAJC5 Proteine) genotype of hOGG1 correlated strongly with the risk of developing ischemic cardiomyopathy.

  10. Polymorphisms of human 8-oxoguanine DNA glycosylase 1 and 8-hydroxydeoxyguanosine increase susceptibility to arsenic methylation capacity-related urothelial carcinoma.

Mouse (Murine) 8-Oxoguanine DNA Glycosylase (OGG1) Interaktionspartner

  1. These findings demonstrate that OGG-1 negatively regulates inflammatory cytokine release by coordinating molecular interaction with the autophagic pathway in hyperoxia-induced lung injury.

  2. These results together, points to a new paradigm about the role of DNA damage and repair by OGG1 in aging and age-associated disease processes.

  3. results implicate hyperglycemia-induced O-GlcNAcylation of Ogg1 in increased mtDNA damage and, therefore, provide a new plausible biochemical mechanism for diabetic cardiomyopathy.

  4. DNA repair protein (zeige ATRIP Proteine) OGG1 bound to its substrate is coupled to DNA occupancy of NF-kappaB (zeige NFKB1 Proteine) and functions in epigenetic regulation of gene expression.

  5. OGG1 plays a protective role in atherosclerosis by preventing excessive inflammasome activation.

  6. OGG1 acts as a STAT1 (zeige STAT1 Proteine) coactivator and has transcriptional activity in the presence of endotoxin

  7. Ogg1 and Mutyh (zeige MUTYH Proteine) regulate hippocampal gene expression related to cognition and behavior, suggesting a role for the glycosylases in regulating adaptive behavior.

  8. Data suggest that OGG1 plays a vital role in the protection of DNA bases from oxidative damage induced by radiofrequency electromagnetic radiation.

  9. Deletion of one or both alleles of ogg1 in mice does increase susceptibility to the toxic effects of aflatoxin B1.

  10. OGG1- DNA base excision repair plays a role in various biological processes that may benefit the host, but when in excess (zeige RCC1 Proteine) could be implicated in disease and/or aging processes.

OGG1 Protein Überblick

Protein Überblick

This gene encodes the enzyme responsible for the excision of 8-oxoguanine, a mutagenic base byproduct which occurs as a result of exposure to reactive oxygen. The action of this enzyme includes lyase activity for chain cleavage. Alternative splicing of the C-terminal region of this gene classifies splice variants into two major groups, type 1 and type 2, depending on the last exon of the sequence. Type 1 alternative splice variants end with exon 7 and type 2 end with exon 8. All variants share the N-terminal region in common, which contains a mitochondrial targeting signal that is essential for mitochondrial localization. Many alternative splice variants for this gene have been described, but the full-length nature for every variant has not been determined.

Alternative names and synonyms associated with OGG1

  • 8-oxoguanine DNA glycosylase (OGG1)
  • 8-oxoguanine DNA glycosylase (ogg1)
  • 8-oxoguanine-DNA glycosylase 1 (OGG1)
  • 8-OXOGUANINE DNA GLYCOSYLASE (ECU08_0770)
  • 8-oxoguanine-DNA-glycosylase (CAC2707)
  • 8-oxoguanine DNA glycosylase (BBOV_I004290)
  • 8-oxoguanine DNA glycosylase (Smp_074010.1)
  • 8-oxoguanine DNA-glycosylase (ogg1)
  • N-glycosylase/DNA lyase (ogg1)
  • 8-oxoguanine DNA glycosylase (Tb927.4.2480)
  • 8-oxoguanine DNA glycosylase (Ogg1)
  • 8-oxoguanine DNA-glycosylase 1 (Ogg1)
  • 8-oxoguanine-DNA glycosylase 1 Protein
  • 19.m02329 Protein
  • ARABIDOPSIS 8-OXOGUANINE-DNA GLYCOSYLASE 1 Protein
  • ATOGG1 Protein
  • DDBDRAFT_0184479 Protein
  • DDBDRAFT_0233024 Protein
  • DDB_0184479 Protein
  • DDB_0233024 Protein
  • F8K7.14 Protein
  • F8K7_14 Protein
  • HMMH Protein
  • HOGG1 Protein
  • Mmh Protein
  • MUTM Protein
  • ogg1 Protein
  • OGH1 Protein
  • Tb04.1H19.930 Protein
  • zgc:158858 Protein

Bezeichner auf Proteinebene für OGG1

8-oxoguanine DNA glycosylase , N-glycosylase/DNA lyase , 8-OXOGUANINE DNA GLYCOSYLASE , 8-oxoguanine-DNA-glycosylase , DNA-formamidopyrimidine glycosylase , 8-oxoguanine-DNA glycosylase 1 , 8-oxoguanine DNA-glycosylase 1 , n-glycosylase/DNA lyase-like , 8-hydroxyguanine DNA glycosylase , AP lyase , DNA-apurinic or apyrimidinic site lyase , OGG1 type 1f

GENE ID SPEZIES
460152 Pan troglodytes
700481 Macaca mulatta
733253 Xenopus laevis
771001 Gallus gallus
791194 Danio rerio
838775 Arabidopsis thaliana
859629 Encephalitozoon cuniculi GB-M1
1118890 Clostridium acetobutylicum ATCC 824
4837452 Scheffersomyces stipitis CBS 6054
5477294 Babesia bovis T2Bo
8346251 Schistosoma mansoni
8628782 Dictyostelium discoideum AX4
9329243 Arabidopsis lyrata subsp. lyrata
100195518 Salmo salar
100380072 Xenopus (Silurana) tropicalis
100432840 Pongo abelii
3656775 Trypanosoma brucei brucei strain 927/4 GUTat10.1
4968 Homo sapiens
81528 Rattus norvegicus
484666 Canis lupus familiaris
520497 Bos taurus
18294 Mus musculus
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