NEIL3 Proteine (NEIL3)

Bezeichnung:
Nei Endonuclease VIII-Like 3 (E. Coli) Proteine (NEIL3)
Auf www.antikoerper-online.de finden Sie aktuell 3 Nei Endonuclease VIII-Like 3 (E. Coli) (NEIL3) Proteine von 2 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen NEIL3 Antikörper (50) und NEIL3 Kits (12) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 70 NEIL3 Produkte verfügbar.
Synonyme:
AI449477, BC034753, C85903, FGP2, FPG2, hFPG2, hNEI3, MAC12.12, MAC12_12, NEI3, neil3, RGD1310562, zgc:103553
alle Proteine anzeigen Gen GeneID UniProt
Ratte NEIL3 NEIL3 290729  
NEIL3 55247 Q8TAT5
NEIL3 234258 Q8K203

Weitere Synonyme anzeigen

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Weitere Proteine zu NEIL3 Interaktionspartnern

Human Nei Endonuclease VIII-Like 3 (E. Coli) (NEIL3) Interaktionspartner

  1. SNPs in NEIL3 are associated with impulsivity in Native American sample.

  2. Single nucleotide polymorphism (SNP) rs142310826 near the NEIL3 gene showed a genome-wide significant interaction with caffeine consumption .There was no gender difference for this interaction (P = 0.64 for heterogeneity). NEIL3, a gene belonging to the base excision DNA repair pathway, encodes a DNA glycosylase that recognizes and removes lesions produced by oxidative stress.

  3. The abnormal expressions of NEIL1 (zeige NEIL1 Proteine), NEIL2 (zeige NEIL2 Proteine), and NEIL3 are involved in cancer through their association with the somatic mutation load.

  4. NEIL3 rs12645561 SNP TT genotype was associated with increased risk of myocardial infarction.

  5. Polymorphisms within FLT3 (zeige FLT3 Proteine), EGFR (zeige EGFR Proteine), NEIL3, and ALOX5 (zeige ALOX5 Proteine) may contribute to the occurrence of GBM.

  6. Results show that the base excision and strand incision activities of NEIL3 exhibited a non-concerted action, indicating that NEIL3 mainly operates as a monofunctional DNA glycosylase.

  7. one role for Neil3 and NEIL1 (zeige NEIL1 Proteine) is to repair DNA base damages in telomeres in vivo and that Neil3 and Neil1 (zeige NEIL1 Proteine) may function in quadruplex-mediated cellular events, such as gene regulation via removal of damaged bases from quadruplex DNA.

  8. Here we report the construction of bicistronic expression vectors for expressing in Escherichia coli the full-length mouse Neil3 (MmuNeil3), its glycosylase domain (MmuNeil3Delta324), as well as the glycosylase domain of human Neil3 (NEIL3Delta324).

  9. NEIL3 partially rescues an E. coli nth (zeige APEX1 Proteine) nei (zeige PMCH Proteine) mutant from hydrogen peroxide sensitivity. Taken together, repair of certain base damage including base loss in ssDNA may be mediated by NEIL3.

  10. hFPG1 (zeige NEIL1 Proteine) and hFPG2 repair 8-oxoguanine and other DNA oxidation products. (hFPG1 (zeige NEIL1 Proteine) and hFPG2)

Mouse (Murine) Nei Endonuclease VIII-Like 3 (E. Coli) (NEIL3) Interaktionspartner

  1. one role for Neil3 and NEIL1 (zeige NEIL1 Proteine) is to repair DNA base damages in telomeres in vivo and that Neil3 and Neil1 (zeige NEIL1 Proteine) may function in quadruplex-mediated cellular events, such as gene regulation via removal of damaged bases from quadruplex DNA.

  2. Structural insight into the substrate specificity and marked preference of Neil3 for ssDNA.

  3. Our data support the involvement of Neil3 in removal of replication blocks in proliferating cells.

  4. Neil3-dependent repair of oxidative DNA damage in neural stem/progenitor cells is required for maintenance of adult neurogenesis to counteract the age-associated deterioration of cognitive performance.

  5. Here we report the construction of bicistronic expression vectors for expressing in Escherichia coli the full-length mouse Neil3 (MmuNeil3), its glycosylase domain (MmuNeil3Delta324), as well as the glycosylase domain of human Neil3 (NEIL3Delta324).

  6. Neil3 exercises a highly specialized function through accurate molecular repair of DNA in rapidly proliferating cells

  7. Neil3 plays a role in repairing 2,6-diamino-4-hydroxy-5-formamidopyrimidine in vivo.

  8. NEIL3 is localized in the nuclei; Neil3 mRNA was selectively expressed in thymus, spleen and bone marrow

  9. NEIL3 is specifically expressed in brain areas where neurogenesis takes place during development and that its expression is tightly regulated both temporally and spatially. NEIL3 seems to be upregulated in tumor tissues compared to normal tissues.

NEIL3 Protein Überblick

Protein Überblick

NEIL3 belongs to a class of DNA glycosylases homologous to the bacterial Fpg/Nei family. These glycosylases initiate the first step in base excision repair by cleaving bases damaged by reactive oxygen species and introducing a DNA strand break via the associated lyase reaction (Bandaru et al., 2002

Alternative names and synonyms associated with NEIL3

  • nei endonuclease VIII-like 3 (E. coli) (Neil3)
  • nei endonuclease VIII-like 3 (E. coli) (NEIL3)
  • nei endonuclease VIII-like 3 (E. coli) (neil3)
  • GRF zinc finger / zinc knuckle protein (AT5G13920)
  • nei endonuclease VIII-like 3 (LOC100338717)
  • nei endonuclease VIII-like 3 (neil3)
  • nei like 3 (E. coli) (Neil3)
  • AI449477 Protein
  • BC034753 Protein
  • C85903 Protein
  • FGP2 Protein
  • FPG2 Protein
  • hFPG2 Protein
  • hNEI3 Protein
  • MAC12.12 Protein
  • MAC12_12 Protein
  • NEI3 Protein
  • neil3 Protein
  • RGD1310562 Protein
  • zgc:103553 Protein

Bezeichner auf Proteinebene für NEIL3

endonuclease VIII-like 3 , nei like 3 , nei endonuclease VIII-like 3 (E. coli) , nei endonuclease VIII-like 3 , DNA glycosylase FPG2 , DNA glycosylase hFPG2 , DNA glycosylase/AP lyase Neil3 , endonuclease 8-like 3 , nei-like protein 3

GENE ID SPEZIES
290729 Rattus norvegicus
428750 Gallus gallus
471359 Pan troglodytes
475639 Canis lupus familiaris
492463 Danio rerio
549955 Xenopus (Silurana) tropicalis
699618 Macaca mulatta
831239 Arabidopsis thaliana
100017570 Monodelphis domestica
100156631 Sus scrofa
100338717 Oryctolagus cuniculus
100380996 Xenopus laevis
100548485 Meleagris gallopavo
100592038 Nomascus leucogenys
55247 Homo sapiens
515343 Bos taurus
234258 Mus musculus
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