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Results suggest that NDRG2 (zeige NDRG2 ELISA Kits) and prenylated Rab acceptor-1 (PRA1) might act synergistically to prevent signaling of T-cell facto/beta-catenin (zeige CTNNB1 ELISA Kits).
Prenylated Rab acceptor protein 1 (PRA1) was identified as an interacting partner of SNCA.
These findings delineated novel roles of PRA1 in lipid transport and cell migration.
findings show Yip3 acts catalytically to dissociate complexes of endosomal Rabs bound to GDI and to deliver them onto membranes; propose that the conserved Yip proteins serve as GDI-displacement factors for the targeting of Rab (zeige HRB ELISA Kits) GTPases in eukaryotic cells
Coexpression of a PRA1 export mutant or knockdown of PRA1 led to redistribution of LMP1 (zeige PDLIM7 ELISA Kits) and its associated signaling molecules to the endoplasmic reticulum and subsequent impairment of LMP1 (zeige PDLIM7 ELISA Kits)-induced NF-kappaB (zeige NFKB1 ELISA Kits) activation.
in vivo modulation of PRA1 may be involved in TCF (zeige HNF4A ELISA Kits)/beta-catenin (zeige CTNNB1 ELISA Kits) signaling, as well as cellular proliferation and tumorigenesis
PRA1 plays a role in vesicular trafficking between the Golgi and cilia in differentiating and mature rod photoreceptors.
The study reports the identification of a Dexras1 (zeige RASD1 ELISA Kits) interactor, prenylated Rab (zeige HRB ELISA Kits) acceptor domain family member 1, which plays a novel role in adrenocorticotrophic hormone stimulated secretion.
A single C-terminal valine residue (Val185) is essential for the proper dimerization and ER export of prenylin.
binds prenylated Rab GTPases and VAMP2\; may play a role in vesicle docking and fusion
prenylated Rab acceptor protein 1
, Rab acceptor 1 (prenylated)
, PRA1 domain family 1
, PRA1 family protein 1
, prenylated Rab acceptor 1
, GTP binding protein associated protein 1
, PRA1 family protein 2