anti-Human LILRB1 Antikörper für Immunohistochemistry (Frozen Sections)

Recommended LILRB1 Antibody (geliefert von: Anmelden zum Anzeigen )

Antigen
Leukocyte Immunoglobulin-Like Receptor, Subfamily B (With TM and ITIM Domains), Member 1 (LILRB1) Antikörper
  • CD85J
  • ILT-2
  • ILT2
  • LIR-1
  • LIR1
  • MIR-7
  • MIR7
  • leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1
  • LILRB1
Reaktivität
Human
123
5
5
Wirt
Maus
84
35
4
Klonalität
Monoklonal
Konjugat
Dieser LILRB1 Antikörper ist unkonjugiert
17
7
7
6
4
4
3
3
3
3
2
2
2
2
2
2
2
1
1
Applikation
Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro))
76
59
32
14
12
8
4
3
2
1
1
1
1
1
Hersteller
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Produktnummer ABIN316937
$ 308.00
Zzgl. Versandkosten $45.00
Relevance Score ABIN Application Konjugat Host Isotype Epitope Hersteller Clonality References Details
1 ABIN2472664 IHC (fro) FACS Mouse IgG1 Anmelden zum Anzeigen 4F9 2
1 ABIN255380 FACS IHC (fro) IHC Mouse IgG1 Anmelden zum Anzeigen 4F9

General

Antigen Leukocyte Immunoglobulin-Like Receptor, Subfamily B (With TM and ITIM Domains), Member 1 (LILRB1) Antikörper
Reaktivität Human
(123), (5), (5)
Wirt Maus
(84), (35), (4)
Klonalität (Klon)
Monoklonal   ( )
Konjugat Dieser LILRB1 Antikörper ist unkonjugiert
(17), (7), (7), (6), (4), (4), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (1), (1)
Applikation Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro))
(76), (59), (32), (14), (12), (8), (4), (3), (2), (1), (1), (1), (1), (1)
Pubmed 2 Publikationen vorhanden
Hersteller Anmelden zum Anzeigen

Produktdetails anti-LILRB1 Antikörper

Target Details LILRB1 Anwendungsinformationen Handhabung Referenzen für anti-LILRB1 Antikörper (ABIN316937) Bilder
Spezifität This antibody is specific for CD85j, a member of the leukocyte immunoglobulin-like receptor (LIR) family.
Produktmerkmale Synonyms: LIR-3, ILT5, LIR3, HL9, Leukocyte immunoglobulin-like receptor subfamily B member 3,Leukocyte immunoglobulin-like receptor 3, Immunoglobulin-like transcript 5, Monocyteinhibitory receptor HL9, CD85 antigen-like family member A
Reinigung Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant
Immunogen Monocyte derived dendritic cells
Klon 4F9
Isotyp IgG1

Target Details LILRB1

Produktdetails anti-LILRB1 Antikörper Anwendungsinformationen Handhabung Referenzen für anti-LILRB1 Antikörper (ABIN316937) Bilder zurück nach oben
Antigen
Andere Bezeichnung CD85j / LILRB1 (LILRB1 Antibody Abstract)
Hintergrund This gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. The encoded protein belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). The receptor is expressed on immune cells where it binds to MHC class I molecules on antigen-presenting cells and transduces a negative signal that inhibits stimulation of an immune response. It is thought to control inflammatory responses and cytotoxicity to help focus the immune response and limit autoreactivity. Multiple transcript variants encoding different isoforms have been found for this gene. CD85j is a receptor for MHC Class I molecules and ligand binding results in inhibitory signals and down-regulation of the immune response.CD85j is expressed predominantly on B-cells and monocytes, and at lower levels on dendritic cells, T-cells and natural killer (NK) cells.Synonyms: CD85 antigen-like family member J, ILT-2, ILT2, Immunoglobulin-like transcript 2, LILR-B1, LIR-1, LIR1, Leukocyte immunoglobulin-like receptor 1, Leukocyte immunoglobulin-like receptor subfamily B member 1, MIR-7, MIR7, Monocyte/macrophage immunoglobulin-like receptor 7
Gen-ID 10859
UniProt O75022
Pathways Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response

Anwendungsinformationen

Produktdetails anti-LILRB1 Antikörper Target Details LILRB1 Handhabung Referenzen für anti-LILRB1 Antikörper (ABIN316937) Bilder zurück nach oben
Applikationshinweise Flow Cytometry: 1/50 - 1/200. Immunohistochemistry on frozen sections: 1/100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Beschränkungen Nur für Forschungszwecke einsetzbar

Handhabung

Produktdetails anti-LILRB1 Antikörper Target Details LILRB1 Anwendungsinformationen Referenzen für anti-LILRB1 Antikörper (ABIN316937) Bilder zurück nach oben
Konzentration 1.0 mg/mL
Buffer PBS containing 0.09 % Sodium Azide as preservative
Konservierungsmittel Sodium azide
Vorsichtsmaßnahmen This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung 4 °C/-20 °C
Informationen zur Lagerung Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch. Caution: (A full Health and Safety assessment is available upon request) This product containsSodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled bytrained staff only.
Haltbarkeit 12 months

Referenzen für anti-LILRB1 Antikörper (ABIN316937)

Produktdetails anti-LILRB1 Antikörper Target Details LILRB1 Anwendungsinformationen Handhabung Bilder zurück nach oben
Allgemeine Veröffentlichungen

Colonna, Nakajima, Navarro, López-Botet: "A novel family of Ig-like receptors for HLA class I molecules that modulate function of lymphoid and myeloid cells." in: Journal of leukocyte biology, Vol. 66, Issue 3, pp. 375-81, 1999

Borges, Hsu, Fanger, Kubin, Cosman: "A family of human lymphoid and myeloid Ig-like receptors, some of which bind to MHC class I molecules." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 159, Issue 11, pp. 5192-6, 1998