anti-Human Lipocalin 2 Antikörper für Intracellular Flow Cytometry

Recommended Lipocalin 2 Antibody (geliefert von: Anmelden zum Anzeigen )

Antigen
Lipocalin 2 (LCN2) Antikörper
  • LCN2
  • 24p3
  • MSFI
  • NGAL
  • AW212229
  • Sip24
  • lipocalin 2
  • lipocalin 2-like
  • LCN2
  • Lcn2
  • LOC100352980
Reaktivität
Human
304
117
109
40
30
2
1
1
Wirt
Ratte
210
189
44
35
3
2
Klonalität
Monoklonal
Konjugat
Unkonjugiert
57
28
21
9
7
7
7
6
6
6
6
6
6
6
6
6
6
6
3
2
2
2
1
1
1
1
1
1
1
1
1
Applikation
Intracellular Flow Cytometry (ICFC)
338
332
137
108
29
26
21
17
13
7
5
4
4
2
2
2
2
2
1
1
1
1
1
Hersteller
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Bilder

Produktnummer ABIN2665287
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General

Antigen Lipocalin 2 (LCN2) Antikörper
Reaktivität Human
(304), (117), (109), (40), (30), (2), (1), (1)
Wirt Ratte
(210), (189), (44), (35), (3), (2)
Klonalität (Klon)
Monoklonal   ( )
Konjugat Unkonjugiert
(57), (28), (21), (9), (7), (7), (7), (6), (6), (6), (6), (6), (6), (6), (6), (6), (6), (6), (3), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Applikation Intracellular Flow Cytometry (ICFC)
(338), (332), (137), (108), (29), (26), (21), (17), (13), (7), (5), (4), (4), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1)
Pubmed 7 Publikationen vorhanden
Hersteller Anmelden zum Anzeigen

Produktdetails

Antigendetails Anwendungsinformationen Handhabung Referenzen Bilder
Reinigung The antibody was purified by affinity chromatography.
Klon M0415B7
Isotyp IgG2a kappa

Antigendetails

Produktdetails Anwendungsinformationen Handhabung Referenzen Bilder zurück nach oben
Antigen
Andere Bezeichnung NGAL (LCN2 Antibody Abstract)
Hintergrund NGAL (lipocalin-2) is a lipocalin family protein that plays important roles in innate immunity, inflammation, and atherosclerosis. It was originally identified as a 25 kD protein covalently bound to gelatinase from human neutrophils. NGAL is a critical component of innate immunity because of its ability to bind iron-siderophore complexes and limit bacterial growth. It is also produced by injured epithelia and is one of the most promising markers for renal epithelial injury and cardiovascular disease (CVD).
Pathways Cellular Response to Molecule of Bacterial Origin, Transition Metal Ion Homeostasis

Anwendungsinformationen

Produktdetails Antigendetails Handhabung Referenzen Bilder zurück nach oben
Applikationshinweise Optimal working dilution should be determined by the investigator.
Beschränkungen Nur für Forschungszwecke einsetzbar

Handhabung

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Konzentration 0.5 mg/mL
Buffer Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
Konservierungsmittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung 4 °C
Informationen zur Lagerung The antibody solution should be stored undiluted between 2°C and 8°C.

Referenzen

Produktdetails Antigendetails Anwendungsinformationen Handhabung Bilder zurück nach oben
Allgemeine Veröffentlichungen

Iqbal, Choudhary, Chan, Wentworth, Higginbotham, Maisel: "Neutrophil gelatinase-associated lipocalin as diagnostic and prognostic tool for cardiovascular disease and heart failure." in: Expert opinion on medical diagnostics, Vol. 7, Issue 2, pp. 209-20, 2013

Singer, Markó, Paragas, Barasch, Dragun, Müller, Budde, Schmidt-Ott: "Neutrophil gelatinase-associated lipocalin: pathophysiology and clinical applications." in: Acta physiologica (Oxford, England), Vol. 207, Issue 4, pp. 663-72, 2013

Leung, Radulovich, Zhu, Organ, Bandarchi, Pintilie, To, Panchal, Tsao: "Lipocalin2 promotes invasion, tumorigenicity and gemcitabine resistance in pancreatic ductal adenocarcinoma." in: PLoS ONE, Vol. 7, Issue 10, pp. e46677, 2012

Palazzuoli, Beltrami, Pellegrini, Nuti: "Natriuretic peptides and NGAL in heart failure: does a link exist?" in: Clinica chimica acta; international journal of clinical chemistry, Vol. 413, Issue 23-24, pp. 1832-8, 2012

Flo, Smith, Sato, Rodriguez, Holmes, Strong, Akira, Aderem: "Lipocalin 2 mediates an innate immune response to bacterial infection by sequestrating iron." in: Nature, Vol. 432, Issue 7019, pp. 917-21, 2004

Goetz, Holmes, Borregaard, Bluhm, Raymond, Strong: "The neutrophil lipocalin NGAL is a bacteriostatic agent that interferes with siderophore-mediated iron acquisition." in: Molecular cell, Vol. 10, Issue 5, pp. 1033-43, 2002

Kjeldsen, Johnsen, Sengeløv, Borregaard: "Isolation and primary structure of NGAL, a novel protein associated with human neutrophil gelatinase." in: The Journal of biological chemistry, Vol. 268, Issue 14, pp. 10425-32, 1993

Bilder

Produktdetails Antigendetails Anwendungsinformationen Handhabung Referenzen zurück nach oben
Bilder des Herstellers
Western Blotting (WB) image for anti-Lipocalin 2 (LCN2) antibody (ABIN2665287) anti-Lipocalin 2 (LCN2) antibody