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Mouse (Murine) CCL2 Protein expressed in Escherichia coli (E. coli) - ABIN1305100
Ernst, Zhang, Hancock, Rutledge, Corless, Rollins: Biochemical and biologic characterization of murine monocyte chemoattractant protein-1. Identification of two functional domains. in Journal of immunology (Baltimore, Md. : 1950) 1994
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Rat (Rattus) CCL2 Protein expressed in Escherichia coli (E. coli) - ABIN1305099
Capsoni, Minonzio, Ongari, Zanussi: A new simplified single-filter assay for 'in vitro' evaluation of chemotaxis of 51Cr-labeled polymorphonuclear leukocytes. in Journal of immunological methods 1989
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Human CCL2 Protein expressed in Escherichia coli (E. coli) - ABIN935639
Frøyland, Pedersen, Kvissel, Almaas, Pharo, Skålhegg, Mollnes, Rootwelt: Effect of acidosis on IL-8 and MCP-1 during hypoxia and reoxygenation in human NT2-N neurons. in Brain research 2006
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Mouse (Murine) CCL2 Protein expressed in Escherichia coli (E. coli) - ABIN935595
Bogen, Dina, Gear, Levine: Dependence of monocyte chemoattractant protein 1 induced hyperalgesia on the isolectin B4-binding protein versican. in Neuroscience 2009
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Human CCL2 Protein expressed in Escherichia coli (E. coli) - ABIN1305101
Rollins, Stier, Ernst, Wong: The human homolog of the JE gene encodes a monocyte secretory protein. in Molecular and cellular biology 1990
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Mouse (Murine) CCL2 Protein expressed in Escherichia coli (E. coli) - ABIN413594
Gray, Di Marco, Okabe, Szyndralewiez, Heitz, Montezano, de Haan, Koulis, El-Osta, Andrews, Chin-Dusting, Touyz, Wingler, Cooper, Schmidt, Jandeleit-Dahm: NADPH oxidase 1 plays a key role in diabetes mellitus-accelerated atherosclerosis. in Circulation 2013
Mouse (Murine) CCL2 Protein expressed in Escherichia coli (E. coli) - ABIN413564
Zhu, Daghini, Chade, Rodriguez-Porcel, Napoli, Lerman, Lerman: Role of oxidative stress in remodeling of the myocardial microcirculation in hypertension. in Arteriosclerosis, thrombosis, and vascular biology 2006
Urine MCP-1 may detect early tubulointerstitial fibrosis in adults with normal kidney function.
p300 (zeige EP300 Proteine) inhibition attenuates both thrombin (zeige F2 Proteine) induced-CCL2 expression and histone H3 (zeige HIST3H3 Proteine) and H4 acetylation in HLFs, suggesting that p300 (zeige EP300 Proteine) is involved in thrombin (zeige F2 Proteine)-induced CCL2 expression via hyperacetylating histone H3 (zeige HIST3H3 Proteine) and H4.
in the presence of autologous platelets, monocytes from older adults synthesized greater MCP-1 than younger adults
Oral and periodontal innate immunity is affected by HIV viremia and ART. GCF (zeige GUCY2F Proteine) IL-8 (zeige IL8 Proteine), G-CSF (zeige CSF3 Proteine), as well as serum IL-8 (zeige IL8 Proteine), MCP-1 and GM-CSF (zeige CSF2 Proteine) may be useful biomarkers for the detection of disease presence and/or its severity due to HIV infection and ART use.
Peptide YY and PP are associated with circulating innate pro-inflammatory cytokines in patients after acute pancreatitis and cumulatively contribute to nearly half of the variance of IL-6 (zeige IL6 Proteine), MCP-1, and TNFalpha (zeige TNF Proteine). Future research is warranted to investigate the signaling pathways that underlie these associations.
The (zeige MLXIP Proteine) level of miR-33 was decreased, whereas the CCL2 level was increas (zeige MLXIP Proteine)ed in the articular cartilage from the osteoarthritis patients compared with the control group.
Studies indicate manipulating CCL2-CCR2 interaction as a potential approach for combating metastatic disease.
CCL2 levels were increased in postmenopausal women with osteoporosis and were linked with decreased bone mineral density and attenuated E2 concentrations.
Interruption of either CCL2-CCR2 (zeige CCR2 Proteine) signaling or cathepsin B (zeige CTSB Proteine) function significantly impaired perineural invasion (PNI (zeige SERPINE2 Proteine)).
The results of this study support the hypothesis that polymorphism in the MCP-1 gene may contribute to the etiology of colorectal cancer
Carvedilol treatment also significantly reduced the levels of proinflammatory cytokines tumor necrosis factor (TNF)-alpha (zeige TNF Proteine), interleukin (IL)-1beta (zeige IL1B Proteine), IL-6 (zeige IL6 Proteine), transforming growth factor (TGF)-beta1 (zeige TGFB1 Proteine) and monocyte chemoattractant protein (MCP)-1 (zeige CPT1B Proteine) in the lung tissue.
Both IL-6 (zeige IL6 Proteine) protein production and transcript levels were downregulated by RA in respiratory tract epithelial cells (LETs) , but upregulated in macrophages (MACs). RA also increased transcript levels of MCP-1 (zeige CPT1B Proteine), GMCSF (zeige CSF2 Proteine), and IL-10 (zeige IL10 Proteine) in MACs, but not in LETs. Conversely, when LETs, but not MACs, were exposed to RA
FSAP (zeige HABP2 Proteine) deficiency causes an increase in CCL2 expression and CCL2-mediated infiltration of leukocytes into the injured vessel
miR (zeige MLXIP Proteine)-33 suppresses CCL2 expression via targeting at the 3'UTR. The miR (zeige MLXIP Proteine)-33/CCL2 axis in chondrocytes regulates the monocyte chemotaxis.
Sca-1(+) progenitor cells found to exhibit increased migration was associated with elevated levels of chemokines, CCL2 (chemokine (C-C motif) ligand 2) and CXCL1 (chemokine (C-X-C motif) ligand 1 (zeige CXCL1 Proteine)), and their corresponding receptors.
that MCP-1 (zeige CPT1B Proteine) inhibition restores glomerular endothelial glycocalyx and barrier function and reduces tissue inflammation in the presence of ongoing diabetic injury
In LLC-bearing mice, the high-fat diet increased and MCP-1 (zeige CPT1B Proteine) deficiency decreased plasma TRAP 5b; neither the high-fat diet nor MCP-1 (zeige CPT1B Proteine) deficiency resulted in significant changes in plasma concentration of osteocalcin (zeige BGLAP Proteine).
Grooved surfaces showed time-dependent increase in soluble mediators involved in cell fusion, CCL2 and MMP-9 (zeige MMP9 Proteine)
In this study, the effect of continuous IL-4 (zeige IL4 Proteine) delivery or bioactive implant coating that constitutively releases a protein inhibitor of CCL2 signaling (7ND) on particle induced osteolysis were studied in the murine continuous femoral intramedullary particle infusion model
Blockade of MCP-1 (zeige CPT1B Proteine) activity significantly reduced inflammatory pleural effusion formation in a CAR model
resence of type 2 diabetes negatively affects the work of cytokines and markers of fibrosis, as evidenced by higher levels of interleukin-1beta and monocyte chemoattractant protein-1, compared with patients without diabetes
Studied SNPs in the bovine toll-like receptor 4 (TLR4 (zeige TLR4 Proteine)) and monocyte chemo attractant protein-1(CCL2) genes.
The LEP (zeige LEP Proteine), IGF2 and CCL2 genes showed allelic expression imbalance in liver, kidney and pituitary glands of Polish Holstein-Friesian bulls.
immune cells and endothelial cells can interact cooperatively to increase CCL2 secretion in the corpus luteum
ghrelin (zeige GHRL Proteine) can inhibit intraplaque angiogenesis and promote plaque stability by down-regulating VEGF (zeige VEGFA Proteine) and VEGFR2 (zeige KDR Proteine) expression, inhibiting the plaque content of macrophages, and reducing MCP-1 expression at an advanced stage of atherosclerosis in rabbits
Data show that peripheral blood endothelial progenitor cells can increase the expressions of chemokines CCL2 and CXCL12 (zeige CXCL12 Proteine) and promote the migration of enhanced green fluorescent protein-positive bone marrow stromal cells to bone defect site.
In a cerebral aneurysm, expression of MCP1 peaked after induction for one week, then decreased. MCP1 induced macrophage adhesion and infiltration in the artery wall of aneurysms, and contributed to the occurrence and development of brain aneurysm.
Data show that the serum levels of mast cell tryptase, monocyte chemoattractant protein-1 (MCP-1) and interleukin-8 (IL-8 (zeige IL8 Proteine)) decreased significantly in Dachengqi decoction treatment group.
measurements of CCL2 and macrophages can serve as new inflammatory biomarkers to evaluate the safety of promising novel microbicides for prevention of HIV.
Expression of MCP-1 was successfully inhibited by transfecting MCP-1 siRNA expression plasmid to the carotid artery, and the progression of atherosclerosis was restricted by RNAi-mediated silencing of MCP-1 expression.
CXCL10 (zeige CXCL10 Proteine) protein was detected in serum from pigs infected with a high virulence African swine fever virus isolate. Levels of CCL2 mRNA were increased in pigs infected with the high virulence isolate compared to a low virulence isolate.
Porcine CCL2 binding on Tuk4+SLA (zeige SLA Proteine)-II- but not on Tuk4-SLA (zeige SLA Proteine)-II+ cells was detected by using a CCL2-green fluorescence protein fusion protein.
The protective properties of flavonoids, such as EGCG, against endothelial inflammation may be regulated in part though induction of HO-1 and subsequent activator protein-1 signaling.
MCP-1 contributes to functional and structural impairment in the kidney in renal artery stenosis, mainly in the tubulointerstitial compartment
Contrast media did not affect bone marrow cell viability/MCP-1 secretion.
Porcine vessel wall injury via balloon arthroplasty upregulates expression of CCL2 by coronary artery transmural and perivascular cells in a sequential pattern.
in the aortic arch expression of monocyte chemoattractant protein 1 (MCP-1) was upregulated, compared with the thoracic aorta
Variable gene expression (eg, matrix metalloproteinase-9 (zeige MMP9 Proteine), CCL2 and Lp-PLA(2 (zeige Lp-PLA2 Proteine)) mRNAs), both in regard to the arterial bed and duration of disease, was associated with variable plaque development and progression.
myocardial infarction induced proinflammatory gene and protein expression in peripheral blood mononuclear cells of tissue factor (zeige F3 Proteine) cyclo-oxygenase-2, monocyte chemoattractant protein-1 and CRP (zeige CRP Proteine)
This gene is one of several cytokine genes clustered on the q-arm of chromosome 17. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The protein encoded by this gene is structurally related to the CXC subfamily of cytokines. Members of this subfamily are characterized by two cysteines separated by a single amino acid. This cytokine displays chemotactic activity for monocytes and basophils but not for neutrophils or eosinophils. It has been implicated in the pathogenesis of diseases characterized by monocytic infiltrates, like psoriasis, rheumatoid arthritis and atherosclerosis. It binds to chemokine receptors CCR2 and CCR4.
small inducible cytokine A2
, C-C motif chemokine 2
, immediate-early serum-responsive JE protein
, immediate-early serum-responsive protein JE
, monocyte chemoattractant protein 1
, monocyte chemoattractant protein-1
, monocyte chemotactic protein 1
, small inducible gene JE
, small-inducible cytokine A2
, monocyte chemotactic and activating factor
, monocyte secretory protein JE
, small inducible cytokine A2 (monocyte chemotactic protein 1, homologous to mouse Sig-je)
, small inducible cytokine subfamily A (Cys-Cys), member 2
, platelet-derived growth factor-inducible protein JE
, acidic seminal fluid protein
, monocyte chemotactic protein 1A
, chemokine CCL2/MCP-1
, antiadrenocorticotropin peptide III
, corticostatin III
, macrophage antibiotic peptide MCP-1
, mast cell protease 1A