Use your antibodies-online credentials, if available.
Keine Produkte auf Ihrer Vergleichsliste.
Ihr Warenkorb ist leer.
Alle Spezies anzeigen
Weitere Synonyme anzeigen
Select your species
Human alpha Defensin 1 ELISA Kit für Sandwich ELISA - ABIN414554
Fraisier, Papa, Granjeaud, Hintzen, Martina, Camoin, Almeras: Cerebrospinal fluid biomarker candidates associated with human WNV neuroinvasive disease. in PLoS ONE 2014
HNP1 upregulation of cytokine expression in pDCs was inhibited by blockade of NF-kappaB (zeige NFKB1 ELISA Kits) activation or knockdown of IRF1 (zeige IRF1 ELISA Kits), demonstrating the importance of these two signaling events in HNP1-induced pDC (zeige PNKD ELISA Kits) activation.
these results demonstrate that HNPs1-3 may be potent inhibitors of ADAMTS13 (zeige ADAMTS13 ELISA Kits) activity, likely by binding to the central A2 domain of VWF (zeige VWF ELISA Kits) and physically blocking ADAMTS13 (zeige ADAMTS13 ELISA Kits) binding.
Increased alpha-defensin expression is associated with risk of coronary heart disease in hyperlipidemia patients.
Levels in sera and CSF (zeige CSF2 ELISA Kits) were elevated in Alzheimer disease patients compared with controls.
the decreased HNP-1 production in the polymorphonuclear phagocytes form elderly individuals might have an important participation in the increased susceptibility to infectious diseases.
Increased levels of neutrophil defensin 1, apolipoprotein E (zeige APOE ELISA Kits), clusterin (zeige CLU ELISA Kits), and zinc-alpha-2-glycoprotein (zeige AZGP1 ELISA Kits) are present in carotid atherosclerotic plaque secretomes.
HNP1 functions as a "molecular brake" on macrophage-driven inflammation, ensuring both pathogen clearance and the resolution of inflammation with minimal bystander tissue damage.
HP1 binding to the chromosomal passenger complex becomes particularly important when Aurora B (zeige AURKB ELISA Kits) phosphorylates kinetochore targets to eliminate erroneous microtubule attachments
data demonstrate that HNP-1 induces IL-8 (zeige IL8 ELISA Kits) production not only through P2Y6 (zeige P2RY6 ELISA Kits), but also through additional P2 receptors via an ERK1/2 (zeige MAPK1/3 ELISA Kits)-dependent mechanism in intestinal epithelial cells.
Results showed that NO and NaNO2 can be considered as factors regulating the chemoattractant properties of defensin HNP1 in neutrophils
Decreased alpha-defensin is associated with intestinal inflammation in a model of inflammatory bowel disease.
cryptdin-1 and cryptdin-4 exhibit circadian oscillation
the Arg5-Glu13 salt bridge in alpha-defensin is conserved for defensin in vivo stability
MMP-7 (zeige MMP7 ELISA Kits) activates mouse paneth cell pro-alpha-defensins
Defensins are a family of microbicidal and cytotoxic peptides thought to be involved in host defense. They are abundant in the granules of neutrophils and also found in the epithelia of mucosal surfaces such as those of the intestine, respiratory tract, urinary tract, and vagina. Members of the defensin family are highly similar in protein sequence and distinguished by a conserved cysteine motif. The protein encoded by this gene, defensin, alpha 1, is found in the microbicidal granules of neutrophils and likely plays a role in phagocyte-mediated host defense. Several alpha defensin genes are clustered on chromosome 8. This gene differs from defensin, alpha 3 by only one amino acid. This gene and the gene encoding defensin, alpha 3 are both subject to copy number variation.
defensin, alpha 1, myeloid-related sequence
, defensin, alpha 2
, myeloid-related sequence
, neutrophil defensin 1
, alpha-defensin 1
, defensin related cryptdin peptide 1
, defensin-related cryptdin peptide
, defensin alpha 1
, Paneth cell-specific alpha-defensin 2
, Neutrophil defensin 1
, Neutrophil defensin 3
, neutrophil defensin 8