Protein Kinase C Substrate 80K-H Proteine (PRKCSH)

Bezeichnung:
Protein Kinase C Substrate 80K-H Proteine (PRKCSH)
Auf www.antikoerper-online.de finden Sie aktuell 9 Protein Kinase C Substrate 80K-H (PRKCSH) Proteine von 4 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen Protein Kinase C Substrate 80K-H Antikörper (89) und Protein Kinase C Substrate 80K-H Kits (8) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 116 Protein Kinase C Substrate 80K-H Produkte verfügbar.
Synonyme:
80K-H, AGE-R2, G19P1, MCD7.9, MCD7_9, MGC75615, MGC82696, PCLD, PKCSH, PLD1, PRIORITY IN SWEET LIFE 4, PRKCSH, VASAP-60, zgc:55653
alle Proteine anzeigen Gen GeneID UniProt
PRKCSH 5589 P14314
PRKCSH 19089 O08795
Ratte PRKCSH PRKCSH 300445  

Weitere Synonyme anzeigen

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Am meisten referenzierte Protein Kinase C Substrate 80K-H Proteine

  1. Human PRKCSH Protein expressed in Escherichia coli (E. coli) - ABIN1047076 : Sakai, Hirai, Minoshima, Kudoh, Fukuyama, Shimizu: Isolation of cDNAs encoding a substrate for protein kinase C: nucleotide sequence and chromosomal mapping of the gene for a human 80K protein. in Genomics 1989 (PubMed)
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Weitere Proteine zu Protein Kinase C Substrate 80K-H Interaktionspartnern

Zebrafish Protein Kinase C Substrate 80K-H (PRKCSH) Interaktionspartner

  1. PRKCSH functions as a chaperone-like molecule, which prevents endoplasmic reticulum-associated degradation of TRPP2.

Pig (Porcine) Protein Kinase C Substrate 80K-H (PRKCSH) Interaktionspartner

  1. PI3K may have a role in nuclear PLD1 regulation; pertussis toxin induced a decrease of LPA-stimulated nuclear PLD1 activity, suggesting that heterotrimeric G(i)/G(0) protein involvement in intranuclear PLD1 regulation(phospholipase D-1)

  2. acetylcholine induces phosphorylation of PLD1 in porcine tracheal smooth muscle.

  3. The results indicate that PKC (zeige FYN Proteine) could be the final target and an integrator molecule of different signaling pathways triggered by angiotensin II (Ang II), which could explain the sustained activation of Na(+)-ATPase by Ang II (zeige AGT Proteine).

Human Protein Kinase C Substrate 80K-H (PRKCSH) Interaktionspartner

  1. Polycystic liver disease is recessive at the cellular level, and loss of functional PRKCSH is an important step in cystogenesis.

  2. The induction of autophagy by hepatocystin deficiency is mediated through mammalian target of rapamycin (mTOR (zeige FRAP1 Proteine)).

  3. Results provide evidence that mutations at the coding PRKCSH GAG repeat are a target of MSI (zeige MSI1 Proteine) and are selectively associated with the MSI (zeige MSI1 Proteine)-H phenotype in gastric carcinomas.

  4. The common SNPs tested in DDOST (zeige DDOST Proteine), PRKCSH and LGALS3 (zeige LGALS3 Proteine) do not seem to be associated with diabetic micro- or macrovascular complications or with type 1 diabetes in Finnish patients.

  5. identified a total of 26 novel mutations in PRKCSH (n = 14) and SEC63 (zeige SEC63 Proteine) (n = 12), including four splice site mutations, eight insertions/ deletions, six non-sense mutations, and eight missense mutations

  6. Our results suggest that PRKCSH gene is not a major genetic cause of PCLD and there may be at least another locus responsible for the disease in Taiwan.

  7. PRKCSH functions as a chaperone-like molecule, which prevents endoplasmic reticulum-associated degradation of TRPP2.

  8. germline mutations in PRKCSH as the probable cause of autosomal dominant polycystic liver disease

  9. role of hepatocystin in carbohydrate processing and quality control of newly synthesized glycoproteins in the endoplasmic reticulum

  10. results identify 80K-H as a new player involved in GLUT4 (zeige SLC2A4 Proteine) vesicle transport and identify a link between a kinase involved in the insulin (zeige INS Proteine) signalling cascade, PKCzeta (zeige PRKCZ Proteine), and a known component of the GLUT4 (zeige SLC2A4 Proteine) vesicle trafficking pathway, munc18c (zeige STXBP3 Proteine)

Mouse (Murine) Protein Kinase C Substrate 80K-H (PRKCSH) Interaktionspartner

  1. TRIM67 regulates Ras signaling via degradation of 80K-H, leading to neural differentiation including neuritogenesis.

  2. Data demonstrate the presence of a binding site on the 3'-untranslated region of NR1 mRNA for AnxA2 and show the regulation of NR1 mRNA by AnxA2, GIIbeta and a third NR1 mRNA-binding protein, which is yet to be identified.

  3. 80K-H is a Ca(2 (zeige CA2 Proteine)+) sensor controlling TRPV5 (zeige TRPV5 Proteine) channel activity

  4. 80K-H is a novel regulator of IP3R1 (zeige ITPR1 Proteine) activity, and it may contribute to neuronal functions.

Cow (Bovine) Protein Kinase C Substrate 80K-H (PRKCSH) Interaktionspartner

  1. This study is the first to report that VASAP-60 is up-regulated in granulosa cells of dominant follicles, to document the primary structure of the VASAP-60 gene and the YY1 (zeige YY1 Proteine) binding to promoter may act as a positive transcriptional regulator.

Protein Kinase C Substrate 80K-H (PRKCSH) Protein Überblick

Protein Überblick

This gene encodes the beta-subunit of glucosidase II, an N-linked glycan-processing enzyme in the endoplasmic reticulum (ER). This protein is an acidic phospho-protein known to be a substrate for protein kinase C. Mutations in this gene have been associated with the autosomal dominant polycystic liver disease (PCLD). Alternatively spliced transcript variants encoding distinct isoforms have been observed.

Alternative names and synonyms associated with Protein Kinase C Substrate 80K-H (PRKCSH)

  • protein kinase C substrate 80K-H (prkcsh)
  • protein kinase C substrate 80K-H (PRKCSH)
  • glucosidase II beta subunit protein PSL4 (PSL4)
  • protein kinase C substrate 80K-H (Bm1_42055)
  • protein kinase C substrate 80K-H (LOC100304710)
  • phospholipase D1, phosphatidylcholine-specific (PLD1)
  • protein kinase C substrate 80K-H (LOC100526729)
  • protein kinase C substrate 80K-H (Prkcsh)
  • 80K-H Protein
  • AGE-R2 Protein
  • G19P1 Protein
  • MCD7.9 Protein
  • MCD7_9 Protein
  • MGC75615 Protein
  • MGC82696 Protein
  • PCLD Protein
  • PKCSH Protein
  • PLD1 Protein
  • PRIORITY IN SWEET LIFE 4 Protein
  • PRKCSH Protein
  • VASAP-60 Protein
  • zgc:55653 Protein

Bezeichner auf Proteinebene für PRKCSH

glucosidase 2 subunit beta , protein kinase C substrate 80K-H , phospholipase D1, phosphatidylcholine-specific , phospholipase D1 , AGE-binding receptor 2 , glucosidase II subunit beta , glucosidase II, beta subunit , hepatocystin , protein kinase C substrate 60.1 kDa protein heavy chain , protein kinase C substrate, 80 Kda protein , PKCSH , alpha glucosidase II, beta-subunit , carbohydrate processing enzyme of the endoplasmic reticulum , glucosidase II beta-subunit , 80K-H protein , vacuolar system associated protein-60 , vacuolar system-associated protein 60

GENE ID SPEZIES
394028 Danio rerio
394983 Xenopus (Silurana) tropicalis
447013 Xenopus laevis
484941 Canis lupus familiaris
835736 Arabidopsis thaliana
6103296 Brugia malayi
100127452 Sus scrofa
100304710 Ictalurus punctatus
100519446 Sus scrofa
100526729 Ictalurus punctatus
100547741 Meleagris gallopavo
100594532 Nomascus leucogenys
100605600 Nomascus leucogenys
5589 Homo sapiens
19089 Mus musculus
338067 Bos taurus
100516540 Sus scrofa
300445 Rattus norvegicus
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